Discussion on traditional Chinese medicine treatment models of depression named "three phases, five internal organs and ten syndromes" / 国际中医中药杂志

Based on the inheritance, the research group summarized the transmissive pathogenesis of depression in three typical stages, formulating the stepward treatment units which included Chinese medicine, acupuncture and TCM characterized psychotherapy, and formed a sequential treatment plan that balanced the principle of strengthening healthy Qi to eliminate pathogens, active and passive treatment, physical therapy and psychotherapy. Based on the retrospective analyses, ten typical clinical syndromes have been formed, constituting the pattern differentiation of "Three Phases, Five internal organs and Ten syndromes" for depression, which sysmatically showed the TCM syndrome differentiation. This work promoted the experiences and methods of treating depression by Chinese medicine.

Impact of Informatization on Medical Staffs Behavior / 医学信息学杂志

The paper points out that informatization development of hospital has three stages,namely,the stage of hospital management informatization,the stage of clinical management informatization and the stage of regional health informatization.It expatiates on the impact of each stage on medical staffs' behavior,points out that informatization is able to increase medical staffs' work efficiency,regulate their diagnosis and treatment behavior and enhance diagnosis and treatment quality.

Comparative Evaluation of Intron Prediction Methods and Detection of Plant Genome Annotation Using Intron Length Distributions

Intron prediction is an important problem of the constantly updated genome annotation. Using two model plant (rice and Arabidopsis) genomes, we compared two well-known intron prediction tools: the Blast-Like Alignment Tool (BLAT) and Sim4cc. The results showed that each of the tools had its own advantages and disadvantages. BLAT predicted more than 99% introns of whole genomic introns with a small number of false-positive introns. Sim4cc was successful at finding the correct introns with a false-negative rate of 1.02% to 4.85%, and it needed a longer run time than BLAT. Further, we evaluated the intron information of 10 complete plant genomes. As non-coding sequences, intron lengths are not limited by a triplet codon frame; so, intron lengths have three phases: a multiple of three bases (3n), a multiple of three bases plus one (3n + 1), and a multiple of three bases plus two (3n + 2). It was widely accepted that the percentages of the 3n, 3n + 1, and 3n + 2 introns were quite similar in genomes. Our studies showed that 80% (8/10) of species were similar in terms of the number of three phases. The percentages of 3n introns in Ostreococcus lucimarinus was excessive (47.7%), while in Ostreococcus tauri, it was deficient (29.1%). This discrepancy could have been the result of errors in intron prediction. It is suggested that a three-phase evaluation is a fast and effective method of detecting intron annotation problems.

Diagnosis and Rehabilitation Treatment in Adhesive Capsulitis of the Shoulder

Adhesive capsulitis was described initially as periarthritis, and then frozen shoulder. Adhesive capsulitis of the shoulder is an insidious, painful condition that results in a gradual restriction of movements. Adhesive capsulitis can be classified into primary or secondary. Primary adhesive capsulitis is an insidious condition, whereas secondary adhesive capsulitis is associated with a known pathology. The pathogenesis remains unclear. Gross pathological changes include thickening and constriction of the capsule, especially anterioinferiorly with a very little amount of synovial fluid in the joint space. Many patients continue to have a significant long-term restriction in their range of motion, although few are functionally restricted. Classically adhesive capsulitis is divided into three phases : the painful phase, the stiff phase, and the resolution phase. The diagnosis of adhesive capsulitis is based on a thorough history taking and physical examination. Radiographs of the shoulder are usually negative. An arthrogram may show a decrease in the intraarticular volume and an absence of the axillary recess. The final confirmation of the diagnosis is made by an experience of relief of pain following an intra-articular anesthetic. Prevention is the ideal treatment. The goals of treatment are to relieve pain, to restore motion, and to restore function. Treatment modalities include anti-inflammatory medications, physical therapy including therapeutic exercise, corticosteroid injection, suprascapular nerve block, capsular distension, manipulation under anesthesia, and arthroscopic capsular release. It is necessary to refine the selection of treatment for individual patients according to the phase of the disease.