ABSTRACT
Objective To explore the effectiveness and significance of neuronavigation in transsphenoidal approach microneurosurgical treatment of pituitary adenoma.Methods A total of 12 patients with pituitary adenomas underwent transsphenoidal surgery.Before the surgery a continuous CT or MRI scanning was adopted,and then the data were inputted into the neuronavigation system for 3-D reconstruction and registration.During the surgery,real-time positioning of the anatomic midline,the anterior wall of the sphenoidal sinus,and the floor of the sella turcica was employed by using the neuronavigation system,as well as the identification of the cavernous sinus and the internal carotid artery to avoid unexpected injury.The extent of tumor resection was assessed postoperatively.Results The mean fiducial error was 2.13?0.94 mm,and the accuracy of targets was