ABSTRACT
Tinea barbae is a dermatophyte infection of the bearded areas of the face and neck. The incidence of tinea barbae has decreased as improved sanitation. We report a case of tinea barbae in a 58-year-old-man, who presented with relatively well-defined erythematous pustular plaque on the upper lip. A fungal culture from tissue of the lesions was grown on Sabouraud dextrose agar and showed typical Trichophyton verrucosum. The nucleotide sequence of internal transcribed spacer for clinical isolate was identical to that of Trichophyton verrucosum strain ATCC 10695. The patient was treated with oral itraconazole for 3 months. The skin lesions improved 3 months after treatment, and recurrence has not been observed.
Subject(s)
Humans , Agar , Arthrodermataceae , Base Sequence , Glucose , Incidence , Itraconazole , Lip , Neck , Recurrence , Sanitation , Skin , Tinea , TrichophytonABSTRACT
Kerion celsi is a severe inflammatory type of tinea capitis that presents as an inflammatory, boggy mass with broken hairs and hair loss. It is usually occurred in children between the age of 4 and 14 years that caused by zoophilic or geophilic pathogens such as Microsporum(M.) canis, Trichophyton(T.) mentagrophytes, T. verrucosum, M. gypseum, T. verrucosum was chiefly found from cattle which infect the human through direct contact. We report a case of kerion celsi caused by T. verrucosum probably transmitted from cattle in a 3-year-old boy. The patient had a solitary, tender, 6.0 x 5.5 cm sized, erythematous boggy plaque and pustules with hair loss on the right side of occipital scalp for 2 weeks. Chains of chlamydoconidia were observed in KOH mount and slide culture by light microscopy. The nucleotide sequence of internal transcribed spacer (ITS) region for clinical isolate was identical to that of T. verrucosum strain IFM 57570. He was treated with 125 mg of terbinafine daily for 12 weeks and short term therapy of low dose of prednisolone. Skin lesion was cured without recurrence.
Subject(s)
Animals , Cattle , Child , Humans , Base Sequence , Hair , Light , Microscopy , Prednisolone , Recurrence , Scalp , Skin , Sprains and Strains , Tinea Capitis , TrichophytonABSTRACT
Kerion Celsi is a highly inflammatory, suppurative fungal infection of the scalp caused by zoophilic or geophilic dermatophytes. We report a case of Kerion Celsi caused by Trichophyton verrucosum in a 19-year-old female presenting with an indurated, pus-discharging, erythematous boggy mass on the frontal scalp for 2 weeks. Restriction fragment length polymorphism shows 100% concordance with Trichophyton verrucosum, which we had maintained as our standard strain. Systemic treatment with steroid and antifungal agents was administered.
Subject(s)
Female , Humans , Young Adult , Antifungal Agents , Arthrodermataceae , Polymorphism, Restriction Fragment Length , Scalp , Sprains and Strains , Tinea Capitis , TrichophytonABSTRACT
Tinea capitis is the most frequent manifestation of dermatophyte infection in children, but is rare in infants less than 1 year of age. Furthermore, Trichophyton(T.) verrucosum as a causative organisum of tinea capitis in infants is documented very rarely. We report a 6-month-old girl with tinea capitis caused by T. verrucosum. The lesion was manifested by round, 2.0x2.0 sized, fine scaly, well-difined erythematous patch on the occiput. Culture from the skin lesion of patient on Sabouraud's dextrose agar showed typical colony of T. verrucosum. The patient was treated with topical lanoconazole application for 1 month.
Subject(s)
Child , Humans , Infant , Agar , Arthrodermataceae , Glucose , Imidazoles , Skin , Tinea , Tinea Capitis , TrichophytonABSTRACT
We report a case of tinea corporis arising in previous burn area which shows tinea imbricata-like clinical appearance in a 69-year-old male. He showed round, 5.0x5.0 cm sized, fine scaly, well-defined erythematous patch with concentrically arranged rings of scales on the right forearm. Histopathologically, PAS staining revealed fungal hyphae in the horney layer of the epidermis. Fungal culture of scales of the lesions on Sabouraud's dextrose agar showed typical Trichophyton verrucosum. He was treated with oral terbinafine (250 mg/day) and topical lanoconazole for 1 month. Skin lesions improved one month after the treatment, and recurrence has not been observed
Subject(s)
Aged , Humans , Male , Agar , Burns , Epidermis , Forearm , Glucose , Hyphae , Imidazoles , Naphthalenes , Recurrence , Skin , Tinea , Trichophyton , Weights and MeasuresABSTRACT
We report a case of tinea corporis with unusual clinical features in a 7-year-old boy. He had a 7.5 x 7.0 cm-sized, well-defined, erythematous patch with concentrically arranged rings of scales on the right thigh, and two 2.5 x 2.0 cm and 1.0 x 1.0 cm-sized satellite lesions beside the lesion. Histopathologically, PAS staining revealed fungal hyphae in the horney layer of the epidermis. Fungal culture of scales of the lesions on Sabouraud's dextrose agar showed typical Trichophyton verrucosum. He was treated daily with 125 mg of terbinafine for 1 month and with topical lanoconazole. Skin lesions improved after a month of treatment, and recurrence was not observed.
Subject(s)
Child , Humans , Male , Agar , Epidermis , Glucose , Hyphae , Recurrence , Skin , Thigh , Tinea , Trichophyton , Weights and MeasuresABSTRACT
BACKGROUND: Trichophyton verrucosum (T. verrucosum) is a zoophilic dermatophyte distributed all around the world. In Korea, kerion celsi caused by T. verrucosum was first reported by Kim et al in the southeast province of Korea. Since then, many patients infected with T. verrucosum have been reported in Young-nam, Chungcheong province, and so on. OBJECTIVE: There have been few reports on the T. verrucosum in Korea, yet. Authors tried to offer the information on dermatophytosis due to T. verrucosum in the various aspects such as prevalence of each year, epidemiology, onset time of the year and season, distribution and characteristics of the regions, sex and age distribution, the clinical types, onset site of the body, and the relation between human beings and infected cattle and so on. METHOD: A total of 218 patients who visited Catholic Dermatologic Clinic in Daegu, Korea from 1986 to 2004, were finally diagnosed as T. verrucosum infection by KOH and fungal culture. The data were based on a retrospective survey of hospital records. However, whenever the information was lacking, we called patients to ask lists of questions for the investigation. RESULTS: The number of patients had increased every year since the first report in 1986. In 1988, the number was up to 44, which was the most. After the year 2000, the number of patients had been decreasing so continuously that there was no case in the year 2003 and 2004. As we see the distribution of province, 47 cases were from Daegu, 137 cases from Kyungsang bukdo, 29 cases from Kyungsang namdo, 5 cases from other provinces and cyties. In the distribution of season, 81 cases appeared in the spring, which was the most. Female to male ratio showed about a 1.2-fold predominance for male. And less than 15-year-old group was 41.3% of total patients. The most frequent onset site was face (36 cases, 16.5%), and the next were arm, trunk, head, leg, neck in the decreasing orders. Classifying the patients by the clinical type, 150 cases (68.8%) were in the tinea circinata type, and the next were kerion celsi type, tinea barbae type, agminated folliculitis type in the decreasing orders. Among 126 cases, 99 patients raised cattle with lesions caused by T. verrucosum, 8 patients raise cattle without lesions, 19 patients didn't breed cattle. CONCLUSION: This investigation is expected to help understand and obtain more information on T. verrucosum infection in Korea.
Subject(s)
Adolescent , Animals , Cattle , Female , Humans , Male , Age Distribution , Arm , Arthrodermataceae , Epidemiology , Folliculitis , Head , Hospital Records , Korea , Leg , Neck , Prevalence , Retrospective Studies , Seasons , Tinea , Tinea Capitis , TrichophytonABSTRACT
BACKGROUND: Tinea barbae(TB) is a rare dermatophytosis localized on the bearded areas of the face and neck. OBJECTIVE: The purpose of this study was to elucidate the epidemiological, clinical and mycological characteristics of TB. METHODS: During the 24-year-period from 1983 to 2004, 74 patients with TB were evaluated in regard to annual incidence, the distribution of the subjects according to age, season, involved site, occupation, a place of residence and concurrent fungal infection. Patients with TB were further assessed concerning causative agents by fungal culture and their association with clinical type and a place of residence. RESULTS: In epidemiologic aspect, annual incidence was increased until 1989, thereafter gradually decreased. TB showed peak incidence in April in monthly distribution. TB occurred predominantly in middle-aged adults, especially in fifties in age distribution and countryfolk in residential distribution. In clinical aspect, superficial type was the most common in clinical types, followed by follicular and kerion type. Upper lip was affected mostly. In mycologic aspect, fungal culture showed positive results in 57 patients. Trichophyton(T.) rubrum was the most common causative agents followed by T. mentagrophytes and T. verrucosum. Thirty six patients had concurrent fungal infection and tinea pedis was the most common. CONCLUSION: The result suggests that although the incidence of TB is decreasing, it is important not only to isolate cattle with dermatophytoses from people but also to treat concurrent dermatophytoses in order to decrease the incidence
Subject(s)
Adult , Animals , Cattle , Humans , Age Distribution , Epidemiologic Studies , Incidence , Lip , Neck , Occupations , Seasons , Tinea Pedis , TineaABSTRACT
Superficial dermatophytic infections are considered to be mild superficial epidermal infection. Most organisms are located superficially in stratum corneum. Sometimes, they may involve the hair follicles, producing papule, pustule, or nodule, characterized clinically as kerion. It usually occurs on scalp or beard area but may occur elsewhere on the body. We report a case of kerion on glabrous skin. The patient presented with intense, boggy mass with suppurations on left thigh. On mycologic examination, Trichophyton verrucosum was isolated. We report this atypical form of localized inflammatory infection caused by tinea.
Subject(s)
Humans , Hair Follicle , Scalp , Skin , Thigh , Tinea , TrichophytonABSTRACT
Superficial dermatophytic infections are considered to be mild superficial epidermal infection. Most organisms are located superficially in stratum corneum. Sometimes, they may involve the hair follicles, producing papule, pustule, or nodule, characterized clinically as kerion. It usually occurs on scalp or beard area but may occur elsewhere on the body. We report a case of kerion on glabrous skin. The patient presented with intense, boggy mass with suppurations on left thigh. On mycologic examination, Trichophyton verrucosum was isolated. We report this atypical form of localized inflammatory infection caused by tinea.
Subject(s)
Humans , Hair Follicle , Scalp , Skin , Thigh , Tinea , TrichophytonABSTRACT
In Korea, kerion celsi caused by Trichophyton(T.) verrucosum was first reported in the Honam area in 1986. Since then, more cases have been reported in the Youngnam and Chungcheong areas but there has been no report in Seoul and Kyonggido until now. Recently, two patients with kerion celsi visited Seoul National University Hospital and T. verrucosum was isolated from the scalp lesions of these patients. Case 1 was 52 year-old female living in Kapyoung, Kyonggido and she showed 10x10 cm and 5x3 cm sized, indurated alopecic masses on the scalp which were developed 2 months ago. Case 2 was a 50 year-old female living in Youngju, Kyongsangbukdo and a 10x7 cm sized, purulent alopecic plaque was developed on the scalp 1 month ago. They were farmers raising cows with gray or whitish plaques on their skins. These patients were successfully treated with terbinafine 250 mg per for 7 weeks and 8 weeds, respectively. We report these cases to call more attention to detect this species even in urban areas such as in Seoul. Therapeutic effect of terbinafine on kerion celsi has not been reported in Korea so far and our cases demonstrated the excellent therapeutic effect of terbinafine on kerion celsi cause by T.verrucosum.
Subject(s)
Female , Humans , Middle Aged , Korea , Scalp , Seoul , Skin , Tinea Capitis , TrichophytonABSTRACT
Kerion celsi presents as an inflammatory, boggy mass studded with broken hairs, oozing purulent material from follicular orifices. This infection is caused most commonly by zoophilic or geophilic dermatophytes and occurs almost exclusively in children. We report a case of kerion celsi caused by Trichophyton (T.) verrucosum in a 67-year-old female, who showed a tender, indurated, swollen, boggy mass exuding pus on the right parietal scalp for 20 days. Culture from a scalp lesion of the patient on Sabouraud dextrose agar showed T. verrucosum. Therapy was initiated with 250 mg of terbinafine daily with almost complete resolution of scalp lesion one month after treatment. No recurrence has been observed to date.
Subject(s)
Aged , Child , Female , Humans , Agar , Arthrodermataceae , Glucose , Hair , Rabeprazole , Recurrence , Scalp , Suppuration , Tinea Capitis , TrichophytonABSTRACT
Although there has been recently noted a nation-wide spread of Trichophyton verrucosum infection in cattle associated with promoted stock raising and dairy farming, there were no case reports in Korean dermatologic literature describing the characteristic clinical features of tinea barbae caused by that particular fungus. We report 3 cases of tinea barbae due to T. verrucosum that developed in male stock farmers breeding cattle. One Patient acted 37, experienced acutely inflamed bo99y tumors on the chin and sub-mandible. The others aged 43 and 46 experienced inflammatory lesions with multiple follicular pustules, crusts and loss of hairs on their upper lips. They were successfully treated with oral griseofulvin and local antifungal ointment combined with short-term oral antibiotics or corticosteroid for about one month.
Subject(s)
Animals , Cattle , Humans , Male , Anti-Bacterial Agents , Breeding , Chin , Fungi , Griseofulvin , Hair , Lip , Tinea , TrichophytonABSTRACT
We report a case of kerion celsi caused by Trichophyton(T.) verrucosum in a 15-year-old male, who showed a trender, indurated, swollen, boggy mass exuding pus on the frontal scalp for 15 days. Culture from a scalp lesion of patient and infected cattles on Sabouraud dextrose agar showed T. verrucosum. Therapy was initiated on with 100mg of itraconazole daily with almost complete resolution of scalp lesion one month after treatment. During the one month follow up reriod, scalp lesion showed new black hairs and no recurrence.
Subject(s)
Adolescent , Humans , Male , Agar , Follow-Up Studies , Glucose , Hair , Itraconazole , Recurrence , Scalp , Suppuration , Tinea Capitis , TrichophytonABSTRACT
Trichophyton verrucosum is a worldwide zoophilic dermatophye. The human infection was first reported in t.he South western part of Korea in 1986 and Fas been increasing in Taegu area. Thirty-one strains of T. verrucosum isolated from the patients in Taegu area were investigated for their mycological features. Gross observation on Sabot rauds dextrose agar, microscopic examination by scotch tape method and slide culture or Sabourauds dextrose agar and potato dextrose agar, and hair perforation test were perforn ed at 37C. The averages of the largest dimensions of the colonies were .9mm at 2 weeks and 59mm at 4 weeks. The morphologic features of the colonies were clasified into three types. Eighteen of 31 strains showed flatwhitish, disc-like colonies with suvmerging hyphae, 11 strains had large radiating follows on the center of the colonies, and 2 strains showed colonies having diffuse fine folds on their surfaces with well-defined borders. On microscopic exaniination, many chlamydospores, antlerlive hyphae, oval and clavate microconidia, and rat tail or string bean shaped macroconidia were observed. It seemed that observation on potato dextrose agar during 10 to 14 days af er inoculation was suitable method for microscopic examination of T. verrucosum. All 31 strains showed positive reaction on hair perforation test.
Subject(s)
Animals , Humans , Rats , Agar , Glucose , Hair , Hyphae , Korea , Solanum tuberosum , Tail , TrichophytonABSTRACT
We report a case of kerion celsi caused by Trichophyton verrucosum in a 4-year-old male. He presented painful, tender, indurated, boggy masses discharing pus on the vertex and occiput. Kerion celsi caued by T. verrucosum was diagnosed by the characteristic gross and microscopic findings of the colony on the Sabourauds glucose. agar. The possible source of infection was searched and wq found that he raised the cattles in his house. They had multiple, scaly, whitish plaques on the skin and T. verrucosum was identified from the hairs of the lesions. He had been treated with griseofulvin and prednisolone, and all lesions were cleared leaving partial alopecia in 2 months.