ABSTRACT
Fungal infections are increasingly being reported in immuno-compromised patients. In this study we report a case of systemic Trichosporon cutaneum infection in an infant with Wilms' tumor. This is the first time that an invasive infection for T. cutaneum has been reported in a Wilms' tumor patient.
As infecções fungicas estão sendo relatadas cada vez mais em pacientes imunocomprometidos. Neste estudo nós relatamos um caso de infecção sistêmica por Trichosporon cutaneum em um infante com tumor de Wilms. Esta é a primeira vez que uma infecção invasiva por T. cutaneum é relatada em paciente com tumor de Wilms.
Subject(s)
Humans , Child , In Vitro Techniques , Mycoses , Diagnostic Techniques and Procedures , Trichosporon/isolation & purification , Wilms Tumor , Methods , PatientsABSTRACT
A 25-year-old woman complaining of dyspnea on exertion, coughing, fever and chills was admitted in January, 1998. Her clinical, radiological, and pathological findings were compatible with hypersensitivity pneumonitis and precipitin antibody to Trichosporon cutaneum was detected in her serum. Although some cases of T. cutaneum-induced hypersensitivity pneumonitis developed during the winter season were reported in Japan, there had been no report of such a case in Korea. This case suggests that T. cutaneum-induced hypersensitivity pneumonitis can develop beyond the summer season in certain environments.
Subject(s)
Adult , Female , Humans , Alveolitis, Extrinsic Allergic , Chills , Cough , Dyspnea , Fever , Hypersensitivity , Japan , Korea , Seasons , TrichosporonABSTRACT
Tricosporon(T.) cutaneum is a member of the subfamily Trichosporideae in the family of Cryptococcaceae. It is now regarded as the same species as Trichosporon beigelii. It is widely distributed in soil, and is sometimes a part of the normal flora of the human skin, nail and mouth. It also may rarely colonize the throat and lower gastointestinal tract in hospitalized patients. T. cutaneum may cause white piedra in immunologically normal patients, a disease characterized by surface hard nodules along the hair shaft, however, skin infection by this organism is rare, T. cutaneum is referred to by Emmons as the agent of subcutaneous and systemic fungal infection. We report a case of subcutaneous infection with T. cutaneum in a kidney transplanted patient.
Subject(s)
Humans , Colon , Hair , Kidney Transplantation , Kidney , Mouth , Pharynx , Piedra , Skin , Soil , TrichosporonABSTRACT
We report the first case of summer-type hypersensitivity pneumonitis(SHP) in Korea diagnosed by positive serum antibodies to Trichosporon cutaneum. Hypersensitivity pneumonitis(HP) has been commonly classified as an occupational respiratory diseases. However, evidence that sensitizing organisms can also contaminate and cause pulmonary diseases in home environment has been increasing. One such disease is SHP. In Japan, 75% of cases with HP are SHP. Even though there has been no known SHP case in Korea yet, there has been high possibility of SHPs in Korea because our country has areas which have hot and humid summer climate similar to Japan. This first case of SHP in Korea suggests that there may be another cases in Korea and nation-wide survey may be required. We report here the first confirmed case of SHP in Korea.
Subject(s)
Antibodies , Climate , Hypersensitivity , Japan , Korea , Lung Diseases , Trichosporon , TrichosporonosisABSTRACT
Tinea pedis is frequently found in those people with poor hygine and in hot and humid environments. The authors investigated the clinical, epidemiologicol a id mycological characteristics of tinea pedis in 138 sewerage workers attending a sewerage plant in Seoul. Tinea pedis was found in 82, with a prevalence of 59.4%. The prevalence of tinea pedis increased with age and the period working at sewerage plant, however, there was no statistical significance. Also there was no difference in the prevalence of tinea pedis between the clerical workers and the field workers. Positive rate for KOH smear was 73.2%, and culture positive rates were 42.7%, producing 35 strains of dermatophytes. Twertyeight strains of Trichophyton Rubrum and 7 strains of Trichophyton mentagrophytes were isolated. Twentyseven yeast-form colonies were isolated, and Trichosporon beigelii was foungl in 19 samples. Most of the yeast forms were found mixed with dermatophytes and moulcis, However, 6 were isolated from direct smear positive cases and yieIded pure colonies of yeast. These included 4 cases of T. beigelii, 1 case of Candida parapsilosis, and 1 case of Candida hormicola. In view of the recent report of these fungi as pathogenic organism, these isolates, rspecially T. beigelii, were considered as a causative agent of tinea pedis in certain groups like sewerage workers.