Exploration and practice of innovation mode of clinical pharmacists training / 中华医学教育探索杂志

In view of the current situation of the construction of clinical pharmacist system and the teaching and training of clinical pharmacist training base in China, this paper provides a reference for perfecting and improving the training mode of clinical pharmacists in China. By establishing a clinical pharmacist system that develops a "two-focus" model, it takes the "trinity" of "hierarchical teaching-innovative practice-stage assessment" as the operating mechanism of teaching management, and the innovative mode of training clinical pharmacist talents with diversified information service platform as the technical support system, thereby providing an effective model for training excellent clinical pharmaceutical care talents.

Exploration of acupuncture treatment for insomnia induced by mental retardation: based on "trinity theory of shaoyang, sanjiao and haishi" / 中国针灸

Insomnia induced by mental retardation is related to the synergistic dysfunction of "shaoyang, sanjiao and haishi (the period of the day from 9 pm to 11 pm) " in pathogenesis. Based on "trinity theory of shaoyang, sanjiao and haishi ", the acupoints of hand and food shaoyang meridians on the head and face (Fengchi [GB 20], Sizhukong [TE 23] and Jiaosun [TE 20]) and those on the four limbs (Sanyangluo [TE 8], Zhongzhu [TE 3], Qiuxu [GB 40] and Xiaxi [GB 43]) are selected to regulate the pivot function of shaoyang. Front-mu and back-shu points (Sanjiaoshu [BL 22], Danzhong [CV 17] and Tianshu [ST 5]), as well as auricular points (Gan [CO12], Dan [CO11] and Sanjiao [CO17]) are chosen to promote qi circulation of shaoyang and sanjiao meridians. In association with the relevant knowledge of time acupuncture at haishi, the circadian rhythm of sleep is set up and the appropriate sleep pattern is developed.

Development of a first-class undergraduate major in bioengineering facing the emerging engineering direction of biomedicine / 生物工程学报

In the "Tutorial for outline of the healthy China 2030 plan", biomedicine was listed as a key planning and development area. Shanghai government also lists biomedicine as an emerging pillar industry. The rapid development of biomedicine industry put higher requirement for talents. Taking the idea of cross integration, mutually beneficial development, inheritance and innovation, the School of Biotechnology of East China University of Science and Technology organically integrates bioengineering and pharmaceutical majors to develop a new undergraduate engineering program of biomedicine, which specially reforms the talent training practice from the aspects of developing a "trinity teaching" standard system, a "three integration, three convergence" curriculum system, and a "three comprehensive education" innovative talent training system. We put forward the trinity of "value guidance, knowledge system, technology and non-technical core competence literacy" to foster emerging biomedicine engineering talents, and developed a comprehensive innovative talents training mode featured by "covering class-in and class-out, covering every student, and covering ideology and curriculum". Moreover, we established effective connections between courses and training goals, between general education courses and professional courses, and between top-notch talent training systems and training programs. Based on the achievements of teaching reform of the emerging engineering program "intelligent bio-manufacturing", the experience we obtained may provide ideas for development of the first-class bioengineering major in China.

Practice and thinking on teaching reform of Chinese medicine course Acupuncture-moxibustion Therapeutics based on "trinity" comprehensive evaluation / 中华医学教育探索杂志

Guided by the emphasis on learning process, the educational reform has designed a "trinity" comprehensive evaluation system (quantitative clinical practice, in-class medical record analysis, and staged comprehensive written test) as the formative evaluation of the course. Through this assessment system, students' self-learning potential is stimulated, clinical skills practice is strengthened, and "taking exams to promote learning and taking exams to promote teaching" is realized. In the practice of teaching reform, it has been found that compared with the conventional teaching class, the students in the teaching reform class have higher participation and are more satisfied with the process assessment of the "trinity" comprehensive evaluation system.

Reform thought and practice on training application-oriented talents of medical laboratory technology specialty by the trinity of "teaching, clinics and research" method / 中华医学教育探索杂志

Medical Laboratory Technology now belongs to the first-level discipline of medical technology and focuses on the cultivation of technical talents.At present,there are some problems in this professional education,such as emphasizing theoretical knowledge teaching,neglecting practical skills training,weak practicability of some courses and graduates' lack of professional quality.In this study,we have combined "Teaching,Clinical and Scientific research" together.By improving the teaching staff,increasing the proportion of experimental courses,clinical skills and scientific research training,relying on "verification-synthesis-design" experiments,laboratory opening and undergraduate scientific research competitions,we have carried out professional personnel training,and have achieved better educational results,which is also helpful to the development of laboratory discipline.

Application of Trinity new model home nursing on continuous control of blood sugar in type 2 diabetes mellitus patients / 中国实用护理杂志

Objective To explore the application of Trinity new model home nursing on continuous control of blood sugar in patients with type 2 diabetes mellitus. Methods Totally 98 patients with type 2 diabetes were selected from January 2016 to December 2017 in our hospital, who were divided into study group and control group by random number table, and there were 49 cases in each group. The control group was given conventional nursing until the hospital was discharged, and the routine follow-up was given after discharge. The study group was given conventional nursing until the hospital was discharged, and the new type of new home nursing mode was given after discharge. The levels of fasting blood glucose (FBG), postprandial 2h blood glucose (2h PBG) and glycated hemoglobin (HbAc1) were compared between the 2 groups at 1d before discharge, 1 months and 3 months after discharge, and the patients compliance were compared, then the quality of life of patients at discharge and 3 months after discharge were assessed by the diabetes specific quality of life scale (DSQL). Results The levels of FBG, 2h PBG and HbAc1respectively were(7.08 ± 0.58) mmol/L, (10.06 ± 0.72) mmol/L, (6.11 ± 0.40)％of the study group at 1d before discharge, of which the control group respectively were(7.07±0.61) mmol/L, (10.07±0.74) mmol/L, (6.10±0.42)％.The levels of FBG, 2h PBG and HbAc1respectively were(6.13±0.44) mmol/L, (9.51 ± 0.55) mmol/L, (5.51 ± 0.30)％of the study group at 1 months after discharge, of which the control group respectively were (6.58 ± 0.56) mmol/L, (9.75 ± 0.53) mmol/L, (5.82 ± 0.34)％ .The levels of FBG, 2h PBG and HbAc1 respectively were(5.69±0.42) mmol/L, (9.03±0.44) mmol/L, (5.22±0.23)％of the study group at 3 months after discharge, of which the control group respectively were (6.17±0.40) mmol/L, (9.46±0.48) mmol/L, (5.51±0.20)％. The levels of FBG, 2h PBG and HbAc1 had significant differences in the interaction between groups and time (F=2.892-5.749, P<0.05). The complete compliance rate of the study group(79.59％, 39/49) was significantly higher than that of the control group (61.22％, 30/49) (χ2=3.967, P=0.046), and then on-compliance rate of the study group (2.04％) was significantly lower than that of the control group (14.29％) (χ2=4.900, P=0.027).The scores of the physiological function, psychology or spirit, social relationship, treatment and DSQL total score of the study group at discharge respectively were (26.62 ± 4.35), (20.21 ± 3.19), (10.36 ± 2.32), (7.42 ± 0.54), (64.61 ± 9.27),of which the control group respectively were(26.49 ± 4.18), (20.17 ± 3.25), (10.45 ± 2.44,(7.35 ± 0.57), (64.46 ± 10.38).The scores of the physiological function, psychology or spirit, social relationship, treatment and DSQL total score of the study group at3 months after discharge respectively were (17.33±3.96), (11.97±2.84), (5.01±1.14), (4.25± 0.49), (38.07±7.12), of which the control group respectively were (21.72±3.51), (15.46±3.08), (7.18±1.85), (5.13 ± 0.48), (49.49 ± 8.74).The scores of the physiological function, psychology or spirit, social relationship, treatment and DSQL total score of the 2 groups at 3 months after discharge were significantly lower than those at discharge (t = 6.117-30.432, all P<0.01), and the scores of each dimension and total score of the study group were significantly lower than those of the control group at 3 months after discharge (t=5.087-8.981, 7.091, all P<0.01). Conclusion The Trinity new model home nursing can obviously improve the blood sugar indexes of patients with type 2 diabetes after discharge, improve the compliance and the quality of life, which has the value of popularization and application.

A morte e a ressurreição do Messias: A Sombra, o Mal e o Anticristo. Um estudo da função ética, pela Psicologia Simbólica Junguiana / The death and resurrection of the Messiah: The Shadow, the Evil and the Antichrist. A study of the ethical function, by Jungian Symbolic Psychology / La muerte y la resurrección del Mesías: La Sombra, el Mal y el Anticristo. Un estudio de la función ética, por la Psicología Simbólica Junguiana

O artigo conceitua o Arquétipo da Sombra como o Arquétipo do Mal na Psicologia Simbólica Junguiana e busca integrá-lo como expressão do Arquétipo Central, ao lado do Arquétipo do Bem. A interpretação de Jung da limitação da imagem de Jeovah na relação com Job é aqui continuada com o reconhecimento do sadismo do Deus patriarcal, que necessita do filicídio sacrificial para transformar-se no Deus da compaixão e do entendimento, pois só assim se tornará a Trindade e expressará o Arquétipo da Alteridade. Em conclusão, o autor segue Jung na interpretação do Apoccomo a Sombra do Novo Testamento e chama a atenção para o texto ser escrito em nome de Jesus, o que sugere a integração do símbolo do Anticristo no mito, como a Sombra de Jesus. ■

The article conceives the archetype of shadow as the archetype of evil in Jungian Symbolic Psychology and tries to interpret it as an expression of the central archetype (Self) side by side with the archetype of good. Jung's interpretation of Jehovah's limitation in the relationship with Job is followed by the recognition of the patriarchal sadism within the Godhead which needs the sacrifice of the Son to be transformed in the God of compassion and understanding because only so will it become the Trinity capable of expressing the archetype of alterity. In conclusion, the author follows Jung in the interpretation of the Apocalypse as the shadow of the New Testament and calls attention for Jesus' shadow expressed in His name as symbol of the integration of the Anti-Christ in the myth. ■

El artículo conceptualiza el Arquetipo de la Sombra como el Arquetipo del Mal en la Psicología Simbólica Junguiana y busca integrarlo como expresión del Arquetipo Central, al lado del Arquetipo del Bien. La interpretación de Jung de la limitación de la imagen de Jeovah en la relación con Job es aquí continuada con el reconocimiento del sadismo del Dios patriarcal, que necesita del filicidio sacrificial para transformarse en el Dios de la compasión y del entendimiento, pues sólo así se convertirá en la Trinidad y expresará el Arquetipo de la Alteridad. En conclusión, el autor sigue a Jung en la interpretación del Apocalipsis como la Sombra del Nuevo Testamento y llama la atención sobre el texto ser escrito en el nombre de Jesús, lo que sugiere la integración del símbolo del Anticristo en el mito, como la Sombra de Jesús. ■

The Influence of the " Trinity System" Talent Training Mode on the Professionalism of Nurses / 中国医学伦理学

This paper firstly analyzed the importance of the nurses' professionalism,and then explained the nurturance advantages of the nurses'professionalism under the" trinity system" talent training and managing mode,including that it is beneficial to improve the students'ability of self-management and self-promotion; to improve their professional accomplishment in an all-round way; to strengthen the professional thought of students; to culti-vate the sense of professional identity of students; to promote professional ability and professional awareness.Final-ly,this paper expounded the influence of the talent training mode of " trinity system" on the nurturance of nurses' professionalism,and highlighted the advantages of enhancement of students'comprehensive quality and ability and the rapid adaptation to the nursing post.

Application of the "Trinity" management mode on operating room efficiency improvement / 中华医院管理杂志

The " Trinity" management model of refined management, PDCA cycle and quality control circle was introduced into operating room ( OR ) management at our hospital since 2017. This practice aims to improve the OR process with refined management, elevate management practice with PDCA cycle, and improve detailed efficiency with quality control circle. 2017 witnessed a significant increase of the hospital in the number of surgical procedures, the punctuality rate of anesthesia, and the punctuality rate of the first surgery, as well as OR turnaround times than 2016. This model plays an important role in improving the efficiency of the OR, thus raising business revenue of the hospital.

Analysis on theory and mode of wastes reclamation in process of industrialization of Chinese materia medica resources / 中草药

With the rapid development of Chinese materia medica (CMM) industry, ecological problems brought by CMM wastes in the process of industrialization of traditional Chinese medicine have become increasingly serious. This article analyzes the pattern of CMM wastes resource utilization deeply based on the externality theory of economics, theory of circular economy and value innovation. It comes up with trinity comprehensive utilization mode, which is the combination of extensive low utilization mode, conversion efficiency utilization mode, and high value-added utilization mode. Finally it puts forward specific measures in the process of industrialization of CMM waste resources development technology and resources management value-added.

De novo transcriptome assembly, functional annotation and differential gene expression analysis of juvenile and adult E. fetida, a model oligochaete used in ecotoxicological studies

BACKGROUND: Earthworms are sensitive to toxic chemicals present in the soil and so are useful indicator organisms for soil health. Eisenia fetida are commonly used in ecotoxicological studies; therefore the assembly of a baseline transcriptome is important for subsequent analyses exploring the impact of toxin exposure on genome wide gene expression. RESULTS: This paper reports on the de novo transcriptome assembly of E. fetida using Trinity, a freely available software tool. Trinotate was used to carry out functional annotation of the Trinity generated transcriptome file and the transdecoder generated peptide sequence file along with BLASTX, BLASTP and HMMER searches and were loaded into a Sqlite3 database. To identify differentially expressed transcripts; each of the original sequence files were aligned to the de novo assembled transcriptome using Bowtie and then RSEM was used to estimate expression values based on the alignment. EdgeR was used to calculate differential expression between the two conditions, with an FDR corrected P value cut off of 0.001, this returned six significantly differentially expressed genes. Initial BLASTX hits of these putative genes included hits with annelid ferritin and lysozyme proteins, as well as fungal NADH cytochrome b5 reductase and senescence associated proteins. At a cut off of P = 0.01 there were a further 26 differentially expressed genes. CONCLUSION: These data have been made publicly available, and to our knowledge represent the most comprehensive available transcriptome for E. fetida assembled from RNA sequencing data. This provides important groundwork for subsequent ecotoxicogenomic studies exploring the impact of the environment on global gene expression in E. fetida and other earthworm species.

Precise,informationized and systematic system of quality of care and safety / 中华医院管理杂志

Quality of care and safety are the lifeline of hospital performance and hospital management.With reference to the KTQ hospital quality certification system of Germany,Tongji Hospital built platforms to supervise outpatient,emergency,inpatient,surgical operation,nursing, hospital-acquired infection,and pharmacy management.By the connection and reaction of both online and offline systems,Tongji Hospital has built a systematic,informationized and precise medical quality and safety system for large public hospitals,safeguarding quality of care and safety of patients.

Informatization Construction and Application of Hospital Biobank / 医学信息学杂志

〔Abstract〕 The paper introduces the informatization construction status of biobank in Peking University People's Hospital, including construction scope, basic infrastructure, steps as well as informatization management system application status, elaborates the application effect.The informatization construction of biobank could shorten the time of operation and ensure the quality of the samples.

Research on trinity teaching mode of clinical practice / 中华医学教育探索杂志

Objective To investigate the application effect of the new trinity teaching mode of clinical practice,which combines bedside teaching,simulation teaching and web-based teaching to-gether. Methods Totally 375 students of clinical medicine,enrolled into Guangzhou Medical Univer-sity in 2006,were randomly divided into department I of clinical medicine (control group,188 stu-dents)and department II of clinical medicine (experimental group,187 students). The students of these two groups were taught respectively with the conventional bedside teaching mode and the trinity teaching mode. Then at the end of clinical practice,assessment results of comprehensive theory and clinical skill in the graduation exam were compared by t test (significance level α=0.05)using SPSS 17.0 software and the questionnaire results of students in experimental group were analyzed. Results There were statistical differences in comprehensive theory and clinical skill assessment scores between two groups(P<0.05). The questionnaire survey showed an approval rate of 92.73%(153/165)for trini-ty teaching mode. Conclusions Facing the shortage of clinical teaching resources,the trinity teach-ing mode is better than the simple bedside teaching mode. The trinity teaching mode can alleviate the pressure brought by the lack of clinical teaching resources at present,create more learning and prac-ticing opportunities for students,and improve the effects of clinical practice teaching.

Construction of the 'trinity' curriculum system of medical english majors / 国际中医中药杂志

To maintain the competitive superiority,the medical english majors should optimize and construct the characteristic curriculum system in order to cultivate high-quality professionals of medical english.Taking the medical english major of Beijing University of Chinese Medicine for an example,this paper discusses the theoretic consideration and practice in constructing the characteristic ‘trinity’ curriculum system of medical english majors,hoping that more attention can be paid to its further development.