A retrospective study on ectopic pregnancy at tertiary care hospital: a two-year study

Background: Over the last few decades, the incidence of ectopic pregnancy has increased almost to extent of an epidemic disease. The rate of ectopic pregnancy has increased from 0.5% in 1970 to 2% today. The aim of this study was to determine incidence, clinical presentation, risk factor, treatment, morbidity and mortality associated with ectopic pregnancy.Methods: The present retrospective study was conducted over a period of 2 year in department of obstetrics and gynaecology, JMCH, Jhalawar from Jan 2015 to Dec 2017. A total of 64 patients with ectopic pregnancy were analyzed.Results: Total 64 cases of ectopic pregnancy were admitted in this duration and total no. deliveries in these 2 year was 18176. So, incidence of ectopic pregnancy at our institute is 0.35%. Most common presenting complain was pain abdomen (in 93.75%) cases. Classical triad of pain, amenorrhea and bleeding was present in 48.3% cases.Conclusions: Early diagnosis and timely intervention in the form of medical treatment or conservative surgery not only reduces maternal morbidity but also preserves future fertility.

Study of Trophoblasts and Histological Changes of Fallopian Tube in Tubal Pregnancy and Anatomical Considerations for Its Early Rupture.

Fertilisation takes place in the lumen of fallopian tube, from where, aided by the ciliated columnar epithelium of the tube, the fertilised ovum makes its way into uterine cavity and the implantation occurs. The passage of fertilised ovum into uterine cavity is delayed or obstructed by developmental, mechanical or other defects which lead to tubal gestation. The incidence varies from 1 in 300 to 1 in 150 pregnancies and it contributes significantly to the maternal mortality and morbidity. Early diagnosis and therapy has helped to reduce the maternal death due to ectopic pregnancy. However, study on histological changes of early ectopic pregnancy are rather scarce and therefore, the present study was conducted on 25 patients of ectopic pregnancy specimens observed for the mode and extent of invasion of chorionic villi, and the histological changes in wall of the fallopian tubes to evaluate the causes of early tubal rupture as well as estimation of gestational age by the study of chorionic villi.