ABSTRACT
Objective To observe the clinical effects of turbuhaler training whistle combined with tracking health interven-tion after using turbuhaler inhalants in asthmatic patients .Methods Sixty cases of mild and moderate asthma treated in the respira-tory outpatient department of this hospital from June to December 2015 were selected as the research subjects .All patients were di-vided into the control group(conventional method) and observation group(turbuhaler training whistle combined with tracking health intervention) ,30 cases in each group .The clinical effects ,night symptoms ,lung function(PEF and FEV1) ,ACT score and MARS-A score after 1 month treatment were compared between the two groups .Results The total effective rates of the observation group and control group were 86 .67% and 73 .33% respectively ,the difference was statistically significant (χ2 =5 .66 ,P< 0 .05) .The night symptom ,FEV1 ,PEF ,ACT score and MARS-A score had statistical difference between the two groups (P<0 .05) .Conclu-sion Turbuhaler training whistle combined with tracking health intervention could enhance the clinical effects of asthmatic pa-tients ,decreases night symptoms ,improves the lung function and enhances the medication compliance .
ABSTRACT
Retrospective DUE is the reviewing of drug therapy after the patient has received the medication. Asthma is a common chronic disease in Malaysia. A National Health and Morbidity Survey in 1996 indicated that asthma prevalence in Malaysia was 4.2%. Statistics on the causes of death have noted asthma as one of the 10 principal causes of death (7.3%) in Malaysia. The purpose of the study was to compare drug utilization patterns amongst the asthmat-ics from the past two years (since 2009) in Kedah state. Asthmatics admitted to the hospital in the preceding two years were analyzed by their patient charts. This study focused on both smoker and non smoker asthmatics. It was observed that salbutamol was most commonly prescribed, followed by montelukast and prednisolone. In the combination therapy, the most commonly prescribed was Symbicort, followed by seretide and combivent. Corticoste-roids constituted the most prevalent class, followed by beta-2 agonists, leukotriene modifiers and methylxanthines. The study presented the most recent scenario on drug utilization pattern of asthmatics in Kedah state.
ABSTRACT
Retrospective DUE is the reviewing of drug therapy after the patient has received the medication. Asthma is a common chronic disease in Malaysia. A National Health and Morbidity Survey in 1996 indicated that asthma prevalence in Malaysia was 4.2%. Statistics on the causes of death have noted asthma as one of the 10 principal causes of death (7.3%) in Malaysia. The purpose of the study was to compare drug utilization patterns amongst the asthmat-ics from the past two years (since 2009) in Kedah state. Asthmatics admitted to the hospital in the preceding two years were analyzed by their patient charts. This study focused on both smoker and non smoker asthmatics. It was observed that salbutamol was most commonly prescribed, followed by montelukast and prednisolone. In the combination therapy, the most commonly prescribed was Symbicort, followed by seretide and combivent. Corticoste-roids constituted the most prevalent class, followed by beta-2 agonists, leukotriene modifiers and methylxanthines. The study presented the most recent scenario on drug utilization pattern of asthmatics in Kedah state.
ABSTRACT
Objective To observe the clinical effect of modified Zhisou powder and Symbicort Turbuhaler simultaneously on patients with Cough Variant Asthma. Methods 120 patients with Cough Variant Asthma were randomly recurited into two groups. 60 patients in the treatment group were treated with modified Zhisou powder and Symbicort Turbuhaler; 60 patients in the control group were treated with Symbicort Turbuhaler. 4 weeks was a therapeutic course in both group. Results The markedly controlled rate (MCR) (clinical control+excenence)of the treatment group was 83.3%, obviously surpassed the control group (70.0%) (P＜0.05); There was obvious improvement of cough, expectoration, breath lessness and throaty pruritus after the therapy in both groups, but it was much better in the treatment group than the control group(P＜0.05). The pulmonary function was significantly improved after treatment in both groups(FEV1, FEV1% and PEF, P＜0.05). The improvement showed significant difference between the two groups(P＜0.05). There was obvious decrease of EOS, IL-5 and ECP in both groups. The decrease of ECP and IL-5 in the treatment group was greater than the control group(P＜0.01). Conclusion The therapy of modified Zhisou powder and Symbicort Turbuhaler has advantage over pure western therapy.
ABSTRACT
PURPOSE: The objective of this study was to evaluate skills in handling inhalers and factors associated with these skills among patients with asthma who had undergone treatment at special asthma and allergy clinics in Korea. METHODS: We enrolled 78 subjects who used Turbuhaler and 145 who used Diskus for asthma control at special clinics in 10 university hospitals and visually assessed their skills in handling these inhalers. We also evaluated skills in 137 subjects who had used pressurized metered-dose inhalers (pMDIs) for symptom relief. Age, sex, duration of asthma and inhaler use, smoking status, monthly income, highest grade completed in school and previous instruction for handling inhalers were also measured to evaluate their association with overall inhaler skills. RESULTS: Performance grade was inadequate for 12.8% of participants using Turbuhaler, 6.2% for Diskus, and 23.4% for pMDIs. The success rates for each step in handling the inhalers were relatively high except for the "exhale slowly to residual volume" step, in which success rates ranged from 24.2% to 28.5%. Older age, male sex, lower educational grade, and absence of previous instruction for handling inhalers were associated with inadequate inhaler technique in univariate analysis; however, only older age and absence of previous instruction remained significant independent risk factors in multivariate analysis. CONCLUSIONS: Among Korean asthmatic patients in special asthma and allergy clinics, skills in handling their inhalers were mostly excellent; meanwhile, older age and absence of previous instruction for handling inhalers were associated with inadequate techniques.
Subject(s)
Humans , Male , Asthma , Handling, Psychological , Hospitals, University , Hypersensitivity , Nebulizers and Vaporizers , Risk Factors , Smoke , SmokingABSTRACT
The aims of this study are to compare the efficacy and side effects of intranasal budesonide as a dry powder and as a freonpropelled pressurized aerosol in the treatment of perennial allergic rhinitis and to assess the difference in compliance with the powder and aerosol. The study design was a randomized, double-blind crossover between two treatment groups over a six-week period. Twelve patients with symptomatic perennial allergic rhinitis received 400 microgram of intranasal budesonide administered daily as two puffs/nostril/day of the drug delivered by a freon-propelled aerosol for the first three weeks and as one inhalation/nostril/day of the pure drug powder for the next three weeks. Fourteen adults with allergic rhinitis received the drug in the reverse sequence. Patients recorded daily symptoms on diaries, and, at each clinic visit, adverse effects were recorded. Compliance with the powder and with the aerosol was also evaluated. During the six weeks, there were significant improvements in symptoms in both treatment groups, and the differences in efficacy and compliance with the medication between the two groups were not significant. Adverse effects included headaches, epistaxis, and nasal dryness ; however, they were not serious and equally distributed in the two groups. We conclude that powder and aerosolized budesonide improve the symptoms of perennial allergic rhinitis significantly with little difference in efficacy, side effects, and preference.
Subject(s)
Adult , Humans , Ambulatory Care , Budesonide , Compliance , Epistaxis , Headache , RhinitisABSTRACT
The aims of this study are to compare the efficacy and side effects of intranasal budesonide as a dry powder and as a freonpropelled pressurized aerosol in the treatment of perennial allergic rhinitis and to assess the difference in compliance with the powder and aerosol. The study design was a randomized, double-blind crossover between two treatment groups over a six-week period. Twelve patients with symptomatic perennial allergic rhinitis received 400 microgram of intranasal budesonide administered daily as two puffs/nostril/day of the drug delivered by a freon-propelled aerosol for the first three weeks and as one inhalation/nostril/day of the pure drug powder for the next three weeks. Fourteen adults with allergic rhinitis received the drug in the reverse sequence. Patients recorded daily symptoms on diaries, and, at each clinic visit, adverse effects were recorded. Compliance with the powder and with the aerosol was also evaluated. During the six weeks, there were significant improvements in symptoms in both treatment groups, and the differences in efficacy and compliance with the medication between the two groups were not significant. Adverse effects included headaches, epistaxis, and nasal dryness ; however, they were not serious and equally distributed in the two groups. We conclude that powder and aerosolized budesonide improve the symptoms of perennial allergic rhinitis significantly with little difference in efficacy, side effects, and preference.