Determination and valuation of GAD-Ab in diabetes mellitus / 中国免疫学杂志

Objective:To find out the applied value of Glutamic Acid Decarboxylase(GAD)-Ab in diagnosis,classification nad forecast in diabetesy.Methods:GAD-Ab in serum of 45 patients with type Ⅰ diabetes mellitus was measured by ELISA method,compared with 25 patients in type Ⅱ diabetes and 60 normal persons as control groups.Results:The positive rate of GAD-Ab in type Ⅰ diabetics.On the contrary,there is no positive patients in normal persons.Conclusion:There is applied value of GAD-Ab in diagnosis,classification and was 76 64%(33/43),have significantly difference compared with type Ⅱ diabetics prospection on diabetes.