ABSTRACT
Pigmented purpuric dermatosis (PPD) represents a group of cutaneous lesions exhibiting petechiae, pigmentation, and occasionally telangiectasia in the absence of an associated venous insufficiency or hematological disorder. PPD may resolve spontaneously but tends to persist for months to years. Various treatment modalities such as oral griseofulvin, pentoxifylline, cyclosporine, ascorbic acid, topical corticosteroids, and PUVA therapy have been used with unsatisfactory results. Recently, some studies reported that PPD showed a dramatic response to narrowband ultraviolet B (UVB) phototherapy. In these studies, narrowband UVB phototherapy was an effective treatment method with few side effects. Here, we present the case of a 7-year-old boy with generalized PPD that improved rapidly following narrowband UVB phototherapy.
Subject(s)
Child , Humans , Male , Adrenal Cortex Hormones , Ascorbic Acid , Cyclosporine , Griseofulvin , Pentoxifylline , Phototherapy , Pigmentation , Purpura , PUVA Therapy , Skin Diseases , Telangiectasis , Venous InsufficiencyABSTRACT
BACKGROUND: Several new treatments appear to have higher success rates than previous therapies for the treatment of vitiligo, and targeted phototherapy is an alternative that may prove to be time-efficient and an effective therapeutic option for the management of this condition. OBJECTIVE: The aim of this study was to evaluate the efficacy of targeted broadband UVB phototherapy for the treatment of localized vitiligo. METHODS: Fifty-three vitiliginous patches on thirty-five patients (16 males, 19 females) were treated using a targeted broadband UVB phototherapy device. Treatment was started at 70% of the minimal erythema dose, and then gradually increased. Lesions were treated twice a week for a maximum of 60 treatment sessions. RESULTS: Subjects tolerated treatment well. Forty-one of the fifty-three patches (77.4%) achieved repigmentation on > or =75% of the treated areas. Best results were obtained on the face and neck; 20 of the 24 patches (83.3%) concerned achieved > or =75% repigmentation. The least response was on the hands and feet; 3 of 6 patches (50%) showed > or =75% repigmentation. The results were better for focal type than segmental type vitiligo. CONCLUSION: Targeted broadband UVB phototherapy appears to be highly effective at restoring pigmentation in patients with localized vitiligo.
Subject(s)
Humans , Male , Erythema , Hand , Phototherapy , Pigmentation , VitiligoABSTRACT
Acquired reactive perforating collagenosis (ARPC) is difficult to treat. We herein report 3 cases of ARPC, which have been improved by narrowband UVB phototherapy. They had been treated with topical corticosteroid and oral antihistamine, which had no therapeutic effects on their conditions. They were treated with narrowband UVB phototherapy twice a week and four-week treatments resulted in relief of pruritus in three patients and eight-week treatments lead to significant reduction of skin lesions in two patients. Based on our experience, it is suggested that narrowband UVB phototherapy is a good therapeutic modality for recalcitrant skin lesions and severe pruritus of ARPC.
Subject(s)
Humans , Phototherapy , Pruritus , SkinABSTRACT
A 31-year-old pregnant woman with pruritus in pregnancy was described; she presented with a one-week history of generalized pruritus at gestational age 6 weeks without primary skin lesion. She had no dermatologic problem before pregnancy. Her pruritic symptom was not con-trolled with conventional emollient and topical corticosteroids. Broadband Ultraviolet B(UVB) phototherapy successfully improved her pruritus. UVB phototherapy also worked well after recurrence of pruritus at pregnancy 23rd week. We report herein a case of pruritus in pregnancy successfully treated with broadband UVB phototherapy.
Subject(s)
Adult , Female , Humans , Pregnancy , Adrenal Cortex Hormones , Gestational Age , Phototherapy , Pregnant Women , Pruritus , Recurrence , SkinABSTRACT
There have been no known therapeutic modalities as effective as glucocorticoids for the treatment of chronic intractable atopic dermatitis. However, various attempts including phototherapy with UVB irradiation have been tried to avoid side effects from long term corticosteroids treatment. The therapeutic effect of UVB irradiation in the management of chronic atopic dermatitis was examined. Sixteen patients with atopic dermatitis showing severe itching and lichenified lesions, who were dependent on corticosteroids, were treated with UVB. After applying mineral oil or vaseline, patients received phototherapy. Intractable pruritus subsided or ameliorated after mean 5.2 times of treatments in 10 of 11 patients, and the skin lesions disappeared or improved after mean 13 times of treatments in 9 of 10 patients. No side effects were observed. UVB phototherapy could be avaluable alternate for the treatment of intractable atopic dermatitis.
Subject(s)
Humans , Adrenal Cortex Hormones , Dermatitis, Atopic , Glucocorticoids , Mineral Oil , Petrolatum , Phototherapy , Pruritus , SkinABSTRACT
Pityriasis rosea is sometimes accompanied with considerable pruritus. Ultraviolet B irradiation is reported to be beneficial in relieving pruritus. The purpose was to evaluate the effect of UVB phototherapy on severe pruritus of pityriasis rosea. Nine patients with severe pruritus had UVB irradiation three times a week Five patients became symptom free and three showed a marked improvement. One dropped out. UVB phototherapy could be an effective modality for relieving pruritus in pityriasis rosea.