ABSTRACT
To evaluate the effects of tetramethylpyraze (TPZ) on the collapsed lung during one lung ventilation (OLV), 2.4 adult patients with esophageal cancer,ASA grade Ⅰ-Ⅱ,undergoing esopha-goesophagostomy, were randomly allocated to receiving intravenous infusion with TPZ 4mg?kg~(-1) (group T,n=12) or equivalent volume of normal saline (group C,n=12) in 5 mins before onset of OLV respectively. The ultrastracture of collapsed lungat 90th min following OLV showed that in group C mitochondia swelled, the cristae disappeared, and large vecule appeared, but in group T those remained normal. As compared with those in group C,the Ca~(2+) content in erythrocyte decreased significantly 30 and 60 mins following OLV (P
ABSTRACT
20m, hypertrophy of nuclei, dilatation of T tubules, mutiple intercalated discs and increase of mitochondria and myofibrils. But the atrial cardiac muscle cells with degeneration showed myofibrillar lysis, abnormal Z bands, mitochondrial swelling and extramembranous disruption, sarcoplasmic reticulum proliferation and dilatation,myelin figures formation and interstitial fibrosis These results suggested that the degree of hypertropy and degeneration of atrial cardiac muscle cells was related to the types, injuried size of congenital heart disease and the age, cardiac functional state of patients
ABSTRACT
30nm) accounted for 3.5% of these contacts. The mean maximum diameter of the vesicles was 49.4 nm, the volume density was 0.023 and profile density was 36. The distribution of the vesicles was as following: 29.1% opened onto or touched the abluminal membrane, 44,9% without visible connection to either surfaces, 26% opened onto or touched the luminal membrane. It was concluded that the mechanism of lymph formation in the stomach seems to be different from that of those organs such as heart, liver, kidney and thyroid. The present study suggested that the intercellular pathway may act as the primary route for lymph formation and macromolecule transportation, and the intracytoplasmic vesicular system may also play certain role in the transport of macromolecules.
ABSTRACT
It was reported that a complete antifertility action of alpha-chlorohydrin in combination with glycidol in male rats after a daily oral dose of 5mg/kg and 75mg/kg respectively for two days. Simultaneously some ultrastructural changes including mitochondrial swelling, atrophy of Golgi complex, decreasing in pinocytotic vesicles and stereocilia were found in principal cells of epididymis within 3 days after medication.In this experiment the animals received 3, 6 and 9 courses of treatment respectively, each course included two days of administration with a daily dose mentioned above and eight days of cessation of medication.The specimens of initial segment of epididymis, liver and kidney were taken at the end of 3 rd, 6 th and 9th courses of treatment for electron microscopy.The principal cells of initial segment of epididymis revealed a normal feature at the end of 3 rd and 9 th course of treatment. But at the end of 6 th course of treatment, the atrophy of Golgi complex and the decrease in stereocilia and pinocytotic vesicles were found in some principal cells.Any ultrastructural changs of sperms in the initial segment were not found by electron microscope.There was also mitochondrial changes with striking increase in the density of the matrix and reduction of size in some liver cells at the end of 6 th course of treatment, but not at the end of 3 rd or 9 th course of treatment. The epithelial cells of nephron in all the specimens revealed a normal ultrastructural feature.The results suggest that the ultrastructural changes of the principal cells and the liver cells induced by the mixture of the drugs could be recovered at the end of treatments.