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Objective To explore the clinical efficacy of Baofukang suppository and policresulen in the treat-ment of cervical erosion,and to observe and analyze the safety,thus to provide the basis for clinical treatment.Methods 268 patients with cervical erosion were selected,they were randomly divided into the control group and the observation group,134 cases in each group.The control group was treated with Baofukang suppository on the basis of conventional treatment.The observation group received Baofukang suppository and policresulen treatment.To assess the treatment effect of the two groups,and the wound healing time,improvement of the symptoms or signs and the vaginal adverse reactions were observed.Results The total effective rate of the observation group was 88.81% (119 /134),which was higher than that of the control group 79.85% (107 /134),the difference was statistically significant (χ2 =9.87, P 0.05).Conclusion Baofukang suppository combined with policresulen has better clinical curative effect in the treatment of cervical ero-sion,which can shorten the wound healing time,reduce symptoms or signs of patients,and has high security.
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Objective To investigate the effect of curative and uterine cervical shaping of different loop electrosurgical excision procedure (LEEP) in treatment of chronic cervicitis.Methods Selected 369 patients with chronic cervicitis,and they were divided into shallow ring excision (SRE) group (123 patients),deep ring excision (DRE) group (123 patients) and LEEP conization (LEEPC) group(123 patients).In each group,they were divided into three subgroups according to the degree and type of erosion.The clinical efficacy of three groups were compared after treatment of 3 months.Results The recovery rate of mild uterine cervical erosion with symptom and midrange uterine cervical erosion,granular pattern uterine cervical erosion and simple uterine cervical erosion among three groups had no significant difference (P ＞ 0.05).In LEEPC group,the recovery rate of severe and mastoid uterine cervical erosion were significantly higher than those in SRE group and DRE group [80.49％ (33/41) vs.63.41％ (26/41) and 58.54％ (24/41),88.24％ (45/51) vs.71.43％ (40/56) and 74.55％ (41/55)] (P ＜ 0.05).The satisfactory rate of uterine cervical shaping among three groups had no significant difference (P ＞ 0.05).Conclusions The three kinds of LEEP have a higher satisfactory rate of uterine cervical shaping.However,different surgical procedure on different level and different type have different efficacy.Clinicians need to choose the right surgery according to the patient's condition.
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Objective To investigate the clinical curative effect of dragon's blood combined with optothermal exposure in the treatment of cervical erosion. Methods 477 cases with cervical erosion were divided into two groups randomly which are 277 cases of the intervention group and 200 cases of the control group. The control group was treated with simplicity light-heat therapies and the intervention group was treated with dragon's blood oral,4 tablets each time ,3 times daily combined with optothermal exposure. The clinical outcome of two therapies were observed and compared. Results Control group :261 cases were cured(94. 3%), 11 cases were improved(3.9%) and 5 cases in vain (1.8%) The curative and total effective rate of the intervention and control group were 94. 3% and 75.0% ,98.2%and 92. 9%, respectively. The effective rate, and the vaginal secretion time and volume after operation have statistical significance (P ＜ 0.05). Conclusion The dragons invigorate blood and exhaust silt, convergent hemostatic, acetanilide detumescence, boils. Combined appicration of light-heat illuminate good curative effect, adverse reaction rate ,less in the treatment of cervical erosion.
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Objective To investigate the clinical feature and strategy on diagnosis and treatment of cervical ulcer in Behcet's disease. Methods From Jan 2000 to Apr 2008,the medical documents of 6 cases with cervical ulcer in Behcet's disease were reviewed retrospectively, who were treated in No.2 hospital affiliated to Wenzhou Medical School Results (1) General information : all 6 patients with cervical ulcer were diagnosed as Behcet's disease clinically, the mean age of all patients is 33.5 years. (2) Clinical feature: the initial symptoms was oral ulcer in 5 cases and erythematic nodosum in 1 case. The typical characteristics of cervical ulcer in Behcet's disease was vaginal purulent discharge. Five among 6 cases presented it. The cervical ulcer in Behcet's disease exhibited the following features : the isolated well-defined ulcers with different size and different deep distributed on the uterine cervix, and the top of ulcer was covered by yellow discharge which was not easy to erase. The duration between the onset symptom and cervical ulcer was calculated to be 2.1 to 7 years. (3) Risk factors for cervical ulcer: operation of drawing intrauterine devices (IUD) in 2 cases, artifical abortion in 2 cases, cervical biopsy in 1 cases, and no factors in the other one case was identified. (4)Treatment: The cervical ulcer in Behcet's disease can be treated by the topical application of recombinant bovine basic fibroblast growth factor (rb-bFGF). If ulcer disease existing in other site, systemic corticosteroids management was warranted. (5) Recurrence : 1 case with recurrent disease was observed after 8 months when completing treatment, the other 5 cases did not show recurrence during 3 months-8 years follow-up. Conclusions The cervical ulcer in Behcet's disease most commonly occurred after cervical operation. The diagnosis should be derived from comprehensive symptoms analysis. The topical application of rb-bFGF on ulcer site of cervix could get satisfied outcome. When necessary, systemic corticosteroids administration could be considered.
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CONTEXT AND PURPOSE: Uterine cervical ectopy (cervical erosion) is today considered to be a physiological condition, but there still seems to be a strong tendency towards treating it. The purpose of this study was to review the medical literature for evidence regarding benefits from treating cervical ectopy. METHODS: The following databases were reviewed: Medical Literature Analysis and Retrieval System Online (Medline), Excerpta Medica Database (Embase), Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs) and Cochrane Library databases. In addition, six medical textbooks were consulted. RESULTS: The review showed that: 1) there is probably an association between ectopy and higher risk of Chlamydia trachomatis, human papillomavirus and human immunodeficiency virus infection; 4) there is probably an association between ectopy and cervical intraepithelial neoplasia; 5) there is an association between ectopy and mucous discharge and nocturia; and 6) there is no evidence of an association between ectopy and cervical cancer, or of protection against cervical cancer associated with ectopy treatment. CONCLUSIONS: 1) No data were found in the medical literature to support routine treatment for ectopy; 2) Treatment could be recommended for symptom relief, but more symptoms are attributed to ectopy than could be demonstrated in a controlled study; 3) Further studies to test the hypothesis of protection against cervical cancer associated with treatment are necessary.
CONTEXTO E OBJETIVO: A ectopia do colo do útero é hoje considerada um fenômeno fisiológico, mas parece ainda haver uma forte tendência no sentido da intervenção (tratamento). Este estudo se propõe a realizar revisão da literatura buscando evidências de benefícios conseqüentes ao tratamento da ectopia. MÉTODOS: Pesquisa nas bases Medical Literature Analysis and Retrieval Sysem Online (Medline), Excerpta Medica Database (Embase), Literatura Latino-Americane e do Caribe em Ciências da Saúde (Lilacs), Biblioteca Cochrane e seis livros especializados. RESULTADOS: A revisão mostrou que: 1) existe provavelmente associação de ectopia com infecção cervical por Chlamydia trachomatis, pelo vírus HPV e maior risco de soroconversão para HIV; 2) existe provavelmente associação entre ectopia e neoplasia intra-epitelial cervical; 3) existe associação com mucorréia e nictúria; 4) não existem evidências sobre associação entre ectopia e câncer de colo do útero nem sobre proteção contra este câncer proporcionada pelo tratamento da ectopia. CONCLUSÕES: 1) Não foram encontrados na literatura dados que justifiquem o tratamento rotineiro da ectopia; 2) O tratamento pode ser utilizado para tratar sintomas associados à ectopia, porém mais sintomas são atribuídos à ectopia do que se pôde confirmar em um estudo controlado; 3) Seriam necessários novos estudos para testar a hipótese de proteção contra o câncer de colo proporcionada pelo tratamento.