ABSTRACT
Background: The hemorrhage of the post-partum (HPP) represents a major problem of public health because it hires the vital and obstetrical forecast of the mother in case of delay of taking care. Present study aims at assessing the effectiveness of the administration of 03 tablets of misoprostol in intra-rectal in the taking care of HPP by uterine atony and to determine the épidémio-clinical profile of HPP by atony.Methods: Authors performed a retrospective and descriptive study concerning the effectiveness of the misoprostol in the taking care of HPP by uterine atony. This study started from December 1st, 2016 till March 31st, 2017. The data processing was performed by Epi info 7 and Excel.Results: The rate of HPP represented 3.8% deliveries which 69.4% was due to uterine atony. HPP by uterine atony represented 2.60% deliveries. It happened at the women from 25 to 34 years old (46.16%), pauciparous (76.93%), with a lower working time at 8 hours (71.15%) and having performed at least 4 CPN (63.47%), giving of urgent babies with a medium weight of 3073.43 g. The administration of the misoprostol was efficient in 90.40% and we noticed no side effect or of serious complications during the taking care of HPP by uterine atony.Conclusions: HPP remains another major preoccupation of the obstetricians in our country because it is an emergency that can put into play the vital forecast and which requires a catch in quick load. The administration of 03 tablets (600 µg) of misoprostol in intra-rectal during HPP by uterine atony deserves its place in the armory of taking care because it is a sure method, efficient and easy to manipulate.
ABSTRACT
Background: Postpartum hemorrhage (PPH) is globally one of the most common causes of maternal death, especially in developing country like India. Pregnancy and childbirth involve significant health risks, even to women with no preexisting health problem. The objective of this study was to analyze the role of various interventions in the management of PPH and its complications.Methods: This prospective observational study was conducted in the department of obstetrics and gynecology of Department of Obstetrics and Gynecology, Dr. D Y Patil Medical college, Pimpri, Pune, Maharashtra, India. A total number of 80 cases of postpartum hemorrhage that fulfilled the selection criteria were included. Data collected and analyzed in PPH patients with medical and surgical management.Results: In present study, most of cases were multigravida (60%) and more than 50 percent of patients required blood and blood products. In present study, most of the postpartum bleeding or postpartum hemorrhage (PPH) cases managed by medical methods. Uterotonic drugs (42.5%) This was possible due to early identification and timely intervention.Conclusions: Active management of third stage of labour is recommended in all cases. Seventy percent cases were managed by medical methods while rest of the cases required surgical management. Among the medical management uterotonic drugs and bimanual uterine compression was used while among the surgical methods repair of cervical and vaginal laceration was mostly required.
ABSTRACT
Medicinal plants are the primary source of medicines and main ingredients used by traditional medicine practitioners. Byrsocarpus coccineus Schum and Thonn is one of such plants that have been used in Africa to treat different ailments including augmentation of labour. The aim of this study is to determine the acute toxicity and to screen the in vivo uterotonic effects of the ethylacetate leaf extract of Byrsocarpus coccineus in pregnant rat uterus. Leaves of the Byrsocarpus coccineus were collected, air dried, pounded and extracted using ethanol, ethylacetate, N-butanol and water. The extracts obtained were then used for the acute toxicity study, while the ethylacetate extract was used to assess the in vivo activity in pregnant rat uterus. Ethylacetate and aqueous leaf extracts Byrsocarpus coccineus was found to be relatively non toxic, whereas N-butanol was found to be toxic in rats and mice. Ethanol leaf extract was found to be only relatively toxic in mice. Ethylacetate leaf extract of Byrsocarpus coccineus potentiated the delivery of pregnant rats on days 21 of pregnancy. The results of the abortificient effect of the ethyl acetate extract on the pregnant rats showed no significant difference between the treatment groups compared with the control (p>0.05). There was a significant increase in haemoglobin, white blood cell, platelets and aspartate aminotransferase (p<0.05). Ethylacetate leaf extract of Byrsocarpus coccineus is relatively safe and was found to potentiate the delivery of pregnant rats with no significant change in hepatic and renal functions and this supports the traditional use of this plant to induce labour at terms.