Endometrite fúngica em éguas: diagnóstico e implicações clínico-patológicas / Fungal endometritis in mares: diagnosis and clinicopathological aspects

Este estudo objetivou estabelecer a etiologia e achados clínico-patológicos das endometrites fúngicas. Para tal, realizou-se anamnese, exame ginecológico, cultura, citologia e biópsia endometriais em 85 éguas em idade reprodutiva e que não pariam havia um ano ou mais. Das 85 éguas, 24 (28%) apresentaram exames compatíveis com endometrite infecciosa. Destas, em 20% (5/24), confirmou-se endometrite com envolvimento fúngico. Os fungos isolados foram: Candida guilliermondii, C. tropicalis, C. pseudotropicalis associadas ao Bacillus sp. em uma égua; C. albicans em duas fêmeas (uma associada a Escherichia coli); um caso de Trichosporon penicillatum e um de T. capitatum. Todos animais diagnosticados com endometrite fúngica apresentaram inflamações endometriais moderadas, nos exames de citologia e no histopatológico, sendo estes achados compatíveis com o histórico e o exame reprodutivo destes animais. Destacou-se a presença constante de linfócitos e plasmócitos nos dois exames, assim como das lesões degenerativas no endométrio através da biópsia endometrial. Em 80% (4/5) constataram-se estruturas fúngicas na citologia endometrial, porém no exame histopatológico, não foi possível detectar tais estruturas. Após o estudo pode-se afirmar que a metodologia utilizada foi eficiente para diagnosticar a endometrite fúngica, com destaque para o exame de citologia endometrial, e que este tipo de endometrite teve caráter crônico em todos os animais.

The aim of the present study was to determine the causes and clinical findings of endometritis. The history, reproductive examination and endometrials culture, uterine cytology and biopsy from 85 mares in reproductive age that did not foal a year or more were performed. Twenty four (28%) out of 85 mares had signals compatible with infectious endometritis. From those, 20% (5/24) had fungal involvement, and the agents were: Candida guilliermondii, C. tropicalis, C. pseudotropicalis, in association to Bacillus sp. in one mare; two mares had C. albicans, and one of them associated with Escherichia coli; a case of Trichosporon penicillatum and another of T. capitatum. All animals with fungal endometritis presented moderate endometrial inflammation, at cytology and uterine biopsy, which was compatible with the animal's history and reproductive exam. The endometrial cytology and biopsy revealed numerous lymphocytes and plasmocytes as well as the degenerative lesions in the endometrial biopsy. Fungal structures were presented at the endometrial cytology smears in 80% (4/5) of the mares, however those structures were not detected in the biopsy. In conclusion, the methodology used was efficient to diagnose fungal endometritis, with standing for the examination of endometrial cytology, and the fungal endometritis had chronic character in all animals.

MRI characters of 52 cases of septate uterus / 中华全科医师杂志

Magnetic resonance imaging (MRI) findings of 52 patients with septate uterus were retrospectively analyzed.There were 19 cases of complete septate uterus and 32 cases of partial septate uterus confirmed by hysteroscopy or hysteroscopy combined with laparoscopy,and 1 case without surgery.According to MRI findings,19 cases were diagnosed as complete septate uterus,32 cases as partial septate uterus and 1 case as intrauterine adhesion.The results indicated that MRIcan be used in diagnosis of septate uterus.