Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add filters








Type of study
Language
Year range
1.
China Oncology ; (12)2000.
Article in Chinese | WPRIM | ID: wpr-674752

ABSTRACT

Purpose:To study the etiological role of Val384Asp in hMLH1 gene in gastric and esophageal cancer.Methods:Genomic DNA were extracted from peripheral blood and were subjected to PCR SSCP and DNA sequencing to screen Val384Asp in hMLH1 gene in 79 gastric and 76 esophageal cancer patients, and in 79 and 76 first degree relatives of gastric and esophageal cancer patients respectively, and in 100 healthy persons. Results:There is a significant difference in the frequency of Val384Asp between gastric cancer patients with family history and healthy controls ( P 0.05). Conclusions:The alleles frequency of Val384Asp in Chinese is 3%. It may partly play an etiological role in some of the stomach cancer patients.

SELECTION OF CITATIONS
SEARCH DETAIL