ABSTRACT
After the hemodynamic comparison of venous air volume in 32 rabbits, the following conclusions were derived. 1) The precordial doppler ultrasonography was most sensitive and end titdal CO2 pressure was statistically decreased at 0.1 ml/kg of air. 2) The mean arterial pressure was suddenly decreased at 1 minute after injection of more than 0.25 ml/kg of air, and was furether reduced according to the time. 3) The arterial PCO2 was continuously increased and statistically different from 0.25 ml/kg of air, and the arterial PO2 was suddenly decreased to about 1/3 of the control data. 4) The pulse rate was statistically decreased at more than 0.5 ml/kg of air and shown peaked p wave, arrhythmias, ST depression and premature ventricular contraction on the EKG. There 4 dead rabbits at 1.0 ml/kg of air, so we could conclucle that the fatal dose of rabbits was more decreased than that of the dogs in venous air embolism.