ABSTRACT
Objective: The effect of pingyangmycin(PYM) in treatment of venous-venular malformation(mixed hemangioma) of the children was evaluated. Methods: Three hundred and twenty-five(132 male patients,193 female patients) patients with venous-venular malformation in the facial-neck and limbs and body regions of the children between January 1998 and January 2005 were reviewed.Patients ages were between one month and 12 years.Among others ages of 175 patiets were ≤ 6 month(53.85%).Pingyangmycin was injected into the cavity or in the circumference of the venous-venular malformations,and the injected was repeated every 7-10 days.This process may be repeated 3-5 times. Results: Three hundred and twenty-five patients were followed up for 6 months-7 years.The cured was 162 cases((49.85%)),basically cured was 124 cases(38.15%),getting improvement was 10.46%.Cure and basically cure rate were 88.00%.The total efficiency was 98.46%. Conclusion: This method was a safe,simple and effective therapy for the venous-venular malformation in the facial-neck and body-limbs regions of the children.