ABSTRACT
Quality of life (QoL) is a subjective measure which includes physical, psychological and social health and its relationship with the environment. Leprosy results in progressive damage to peripheral nerves in untreated or inadequately treated patients leading to nerve impairment and visible disabilities which may affect the quality of life. A descriptive cross-sectional study was conducted in a tertiary care centre among patients with leprosy over a period of six months, and quality of life status was evaluated using the WHOQoL Bref questionnaire based on four domains, namely physical, psychological, social and environmental. A total of 50 patients (males: females - 36:14) in the age group of 19-69 years were evaluated. Most patients (64%) belonged to the borderline tuberculoid spectrum. Patients with a disability accounted for 16% (8 out of 50) of the total cases. The psychological domain was the most commonly affected domain among patients. Females had lower scores than males in all domains. Elderly patients, patients with lepromatous leprosy and those with facial involvement had lower scores. Domain outcomes in lepra reactions were lower than in other types of leprosy. The study observed that leprosy in the ageing population, women and patients with severe forms of leprosy, associated with disabilities, have poorer quality of life.
ABSTRACT
Objective: To assess the patterns and predictors of pharmacotherapy and QOL in DFS patients in an Indian tertiary care hospital. Methods: A cross-sectional study was conducted among inpatients with DFS. Data on sociodemographic and clinical factors, pharmacotherapy, clinical outcomes, and QOL were analyzed using the chi-squared test, independent sample t-test, and binary logistic regression. Results: We screened 3284 inpatients and included consecutive 87 (2.7%) DFS patients. The mean age was 56.08 ± 11.05 years, with a male preponderance (75.8%). Mean HbA1c was 9.9 ± 2.483. About 75% of patients received insulin, and polypharmacy was noticed in 82.7%. About 67.8% of DFS patients had other vascular complications of diabetes, with diabetic retinopathy being the most common in 89%. Amputations were noticed in 32.1% of patients. Overall, poor QOL was seen in 79.3% of patients. The mean scores for different domains were as follows: physical, 41.51 ± 14.15; psychological, 42.90 ± 11.16; social relationships, 43.06 ± 19.36; and environment, 47.17 ± 13. The presence of complications from diabetes was a significant predictor of the utilization of antihypertensives (OR: 2.92, CI [1.09, 7.79], P = 0.03) and poor QOL (OR: 4.54, CI [0.965, 21.41], P = 0.05). Conclusion: DFS patients in this study were found to be younger with poor glycemic control and other vascular complications of diabetes. The presence of other complications of diabetes in DFS patients was found to be a predictor of pharmacotherapy and poor QOL.
ABSTRACT
Background: Quality of life is a multidimensional concept. Disability has a shattering effect on the quality of life with a predominantly negative effect on “marriage, educational attainment, employment and emotional state” as it jeopardizes personal, family and social life. Assessment of “quality of life” (QOL) in disabled is essential measure to bring “disabled” to core stream of civilization. Aims & Objectives: To assess the “Quality of Life” among disabled and to determine the “association between socio-demographic” factors with the quality of life. Materials & Methods: A “community based Cross-Sectional study” was conducted in rural area of Dehradun district. Multistage random sampling technique was used to enrol 2600 people in age group of 5- 59 years for the study. Semi-structured questionnaire was used to assess the socio-demographic information while WHO-BREF questionnaire was used to assess the QOL. Results: 61(2.3%) people were found to be disabled. Among those disabled individuals 52.5% were males and 47.5 % were females. In Psychological and Environmental domain, (65.6% & 55.7%) of the study participants respectively were partially satisfied, while 60.7% of the disabled persons were dissatisfied in social domain. However, 68.9 % disabled were satisfied in physical domain. Religion was found to be strong determinant for physical, psychological and environmental domain of QOL (p-value= 0.001, 0.032 and 0.047 respectively). Socio-economic status was also found to be significantly associated with psychological domain (p-value=0.000). Conclusion: Very few individuals were found to be disabled in the present study, but religion was strongly affecting the satisfaction level among disabled. Thus, religious issues should be addressed to improve quality of life among disabled persons and there should be a holistic approach for managing disabled person.
ABSTRACT
Objective To understand the present status and explore the influencing factors of quality of life(QOL)among medical students,so as to provide a reference for the improvement of the QOL. Methods A total of 1 898 medical students sampled by stratified cluster sampling method were recruited and investigated by wHO-BREF scale. The influencing factors were assessed by t-test and one-way ANOVA. The data were analyzed by SPSS 19.0. Results Scores of the physical,psychological,social relationship,environmental domain of quality of life were 64.99±13.28,61.85± 13.79,61.58±14.53,and 54.91±13.91,respectively. The results indicated grade,monthly income of family,physical training,quality of sleep and history of trauma were the influencing factors of QOL among medical students,and the differences were all statistically significant(P<0.05). Con?clusion The score of environmental domain of QOL among medical students was the lowest. In order to improve the QOL of medical students, schools should take different measures to them according to different grades or monthly income.