Secuelas respiratorias clínicas, funcionales y tomográficas de pacientes hospitalizados por Covid-19 al año del diagnóstico: ESTUDIO SECUELAR-19 / Clinical, functional and tomographic respiratory sequels of patients hospitalized for COVID-19 at one year of diag nosis: SECUELAR-19 TRIAL

Resumen Introducción : Hay información escasa sobre evolución a largo plazo de pacientes hospitalizados por neumo nía COVID-19 moderada (NM) y grave (NG). El objetivo del estudio fue determinar impacto clínico, funcional respiratorio y tomográfico (TACAR) luego del alta a 12 meses del diagnóstico. Métodos : análisis según grupos NM y NG, desatura dores (PD) en prueba de caminata 6 min (PC6M) y patrón tomográfico símil fibrótico (SF). Comparamos resultados a 3 y 12 meses de seguimiento. Resultados : 194 pacientes enrolados, evaluados al año: 103 (53% ): masculinos (62.4%), edad 57.7 ± 10.9 años, comorbilidades (hipertensión arterial 38.8%, dia betes 29.6%, antecedentes respiratorios-AR- 18.4%). Com paramos variables a los 3 y 12 meses (media/DE): CVF 84%(19) a 88(19) (p = 0.01); 27% tuvo CVF<80% al año. En PC6M: 426 metros (108) a 447(92) (p = < 0.01). El 12.8% fue PD al año. NG tuvo mayor SF (40% vs. 27.9% p = 0.021). SF se relacionó con CVF <80% (p = 0.004) en toda la co horte, y NG (p < 0.001). Al año en análisis multivariado se asoció a CVF <80%, AR (OR 4.32, 1.15-16.25), diabetes (OR 2.96, 1.02-8.57) y patrón SF (OR 3.51, 1.25-9.88). PD se asoció a AR (OR 12.2, 2.41-61.85). Discusión : Se observó mejoría en todas las variables al año. Pero al año persisten alteraciones funcionales y tomográficas en <50% de los pacientes. El subgrupo de PD se relacionó a AR. Es importante el seguimiento protocolizado de los pacientes hospitalizados, especial mente los grupos NG, PD y SF.

Abstract Introduction : There is scarce information on longterm evolution of hospitalized patients with moderate (MP) and severe (SP) COVID-19 pneumonia. Objective: to de termine clinical, respiratory function, and tomographic (HRCT) impact after being discharged 12 months after diagnosis. Methods : Analysis according to MP and SP, desatura tor patients (DP) in 6-minute walking test (6MWT) and HRCT fibrotic-like pattern (FLP). Results compared at 3 and 12 months of follow-up. Results : 194 patients enrolled and one year later 103 (53%) were evaluated: gender male (62.4%), age 57.7 ± 10.9 years, comorbidities (arterial hypertension 38.8%, diabetes 29.6%, and respiratory diseases-RD-18.4%). Variables compared 3 months to 12 months (mean/SD): FVC: 84%( 19) to 88%( 19) (p= 0.01). A 27% of patients had FVC<80% at one year. In 6MWT:426 (108) to 447 (92) (p = <0.01). 12.8% are DP in one year. SP had a greater FLP than MP (40% vs. 27.9%, p = 0.021). The FLP group was related to FVC < 80% (p = 0.004) in all patients but only in SP (p < 0.001). After one year, in multivariate analysis, FVC < 80% was associated with RD (OR 4.32, 1.15-16.25), diabetes (OR 2.96, 1.02-8.57) and FLP (OR 3.51, 1.25-9.88). DP were associated with RD (OR 12.2, 2.41-61.85). Discussion : Improvement was observed in all vari ables when comparing 3 to 12 months. However, after one year, functional and tomographic alterations persist in less than 50% of patients. DP subgroup was related to RD. Protocolled follow-up of hospitalized patients is important, especially in SP, DP, and FLP groups.

Secuelas respiratorias clínicas, funcionales y tomográficas de pacientes hospitalizados por COVID-19 a seis meses del diagnóstico: estudio SECUELAR-19 / Clinical, functional and tomographic respiratory sequels of patients hospitalized for COVID-19 at six month of diagnosis: SECUELAR-19 trial

Resumen Introducción: Hay información escasa sobre la evolución de los enfermos hospitalizados por neumonía por COVID-19 a mediano plazo. El objetivo de este estudio fue determinar en pacientes con neumonía moderada (NM) o grave (NG) por COVID-19, el impacto clínico, funcional respiratorio y tomográfico a los 6 meses. Métodos: Se realizó análisis según grupos de NM y NG, desaturadores (PD) en la prueba de cami nata de 6 minutos y presencia del patrón tomográfico de alta resolución (TACAR) símil fibrótico. Se compararon los resultados a los 3 y 6 meses. Resultados: Se incluyeron 129 pacientes, edad 57±11 años, comorbilidades frecuentes (hipertensión arterial 38.1%, diabetes 30.4% y respiratorias 18.6%). Al comparar 3 y 6 meses se ob servó mejoría de la calidad de vida en NM y NG. Los PD presentaron menor metraje caminado, peor calidad de vida y mayor presencia de patrón símil fibrótico. Este patrón se relacionó con la caída de la FVC 80% en NM y NG (p = 0.048 y p = 0.007), y con PD (p = 0.002). En el análisis multivariado, el patrón símil fibrótico s e asoció a la reducción de la CVF con OR = 4.44 (1.94-10.18, p<0.01) y a la desaturación, OR = 5.01 (1.63-15.42, p<0.01). En esta cohorte se observó mayor compromiso funcional y tomográfico en los PD. El patrón símil fibrótico se relacionó con peor evolución funcional y oximétrica. Discusión: Es importante el seguimiento de los pacientes con NG, los PD y los que presentan patrón fibrótico al alta de neumonía por COVID-19.

Abstract Introduction: There is scarce information about middle-term evolution of hospitalized patients who suffer from pneumonia caused by COVID-19. The objective of this study is to determine the clinical, respiratory, tomographic and functional impact on COVID-19 patients with moderate (MP) to severe (SP) pneumonia after six months of acute infection. Methods: Analysis was carried out by MP and SP groups, desaturators during the 6-minute-walking test and the presence of fibrotic like pattern on HRCT. Outcomes at 3 and 6 months were compared. Results: The analysis included 129 patients, between 57 ± 11 years old. Frequent comorbidities were: arterial hypertension 38.1%, diabetes 30.4%, respiratory 18.6%). Comparing 3 and 6 months, improvement in quality of life was observed in MP and SP. The DP walked less meters in the MWT, worsened life quality and more fibrotic like pattern. The fibrotic pattern was related to the fall of CVF < 80% on MP and SP (p = 0.048 and p = 0.007), and with DP (p = 0.002). On multivariated analysis, the fibrotic like pattern was associated to the reduction of CVF with OR = 4.44 (1.94-10.18, p<0.01) and desaturation OR = 5.01(1.63-15.42, p < 0.01). On this cohort it was observed more functional and tomographic compromise on the DP The fibrotic like pattern was related to worse functional evolution and oximetry. Discussion: Follow-up after discharge of COVID-19 patients with SP, DP or fibrotic changes in HCRT is underlined.

Application of six-minute walking test in cardiopulmonary function rehabilitation of occupational pneumoconiosis patients / 中国职业医学

As a simple, objective, effective, and repeatable functional testing method, six-minute walk test(6 MWT) was widely used in the physical assessment of patients with chronic cardiopulmonary diseases. The correct evaluation of cardiopulmonary function of patients with occupational pneumoconiosis(hereinafter referred to as pneumoconiosis) has important reference value for their cardiopulmonary rehabilitation. The application of 6 MWT in the cardiopulmonary function rehabilitation of pneumoconiosis patients mainly includes the following: it can accurately evaluate the maximum physical load of pneumoconiosis patients during exercise; comprehensively evaluate the cardiopulmonary function of pneumoconiosis patients, guide the formulation of personalized exercise prescription and improve the practicability of exercise prescription; evaluate the safety of exercise in pneumoconiosis patients; evaluate the effect of exercise rehabilitation; and pre-evaluate the cardiopulmonary function. As a supplement to cardiopulmonary exercise test, it can be used in disability identification of pneumoconiosis patients.The 6 MWT can provide a quantitative index for the assessment of cardiopulmonary function in pneumoconiosis patients, and it is worthy of wide application in the assessment of cardiopulmonary function, exercise ability and respiratory rehabilitation in such patients.

Efeito do treinamento aeróbio em parâmetros cardiorrespiratórios, hemodinâmicos e autonômicos de pacientes com doença renal crônica em hemodiálise / Effect of aerobic training on cardiorespiratory, hemodynamic, and autonomic parameters of chronic kidney disease patients on hemodialysis

A doença renal crônica (DRC) é uma condição clínica de alto risco cardiovascular e os pacientes nos estágios mais avançados da doença que dependem de terapia renal substitutiva frequentemente tem prejuízo cardiorespiratório, níveis elevados de pressão arterial (uso de múltiplas medicações para controle), modulação autonômica prejudicada e graus variados de inflamação. Deste modo este estudo tem como objetivo verificar se o exercício físico aeróbio intradialítico tem impacto em modificar estas alterações. Os pacientes foram selecionados em duas unidades de hemodiálise em São Luís do Maranhão, Brasil, entre junho de 2016 e outubro de 2019, e foram alocados conforme aceitação em grupo controle (GC) e grupo exercício (GE). O GE foi submetido a treinamento aeróbio com bicicleta por um período de 12 semanas. Avaliação física antropométrica, teste de caminhada de 6 minutos (TC6m), ecocardiograma, eletrocardiograma com análise da variabilidade da frequência cardíaca e medidas laboratoriais foram realizadas incluindo interleucina 6 (IL6) antes e após 12 semanas em ambos os grupos. Trinta e um pacientes foram avaliados 15 pacientes no grupo controle (GC) e 16 pacientes no grupo exercício (GE). Após 12 semanas de treinamento houve diminuição da pressão arterial sistólica do grupo exercício em relação ao basal (129,8 ± 9,41mmHg vs 112,00 ± 12,0 mmHg p = 0,03). Não houve alterações na composição corporal e na maioria dos exames laboratoriais, exceto pelo aumento do KTV (índice de adequação de diálise) e diminuição do LDL colesterol no grupo exercício em relação ao grupo controle. No entanto, os níveis de HDL colesterol aumentaram (39,92 ± 6,1 mg/dL vs 48,00 ± 7,85 mg/dL p = 0,02) e IL6 diminuíram (4,56 ± 1,2 pg / mL vs 2,14 ± 1,0 pg / mL p = 0,02). Houve aumento da distância percorrida no teste de caminhada no grupo exercício (473,80 ± 98,6 metros vs 573,50 ± 74,22 metros p = 0,01). Na avaliação ecocardiográfica, verificou-se que no GE houve diminuição da pressão da artéria pulmonar estimada (31,38 ± 2,9 mmhg vs 24,2 ± 1,7 mmhg p = 0,001). Houve melhora na modulação autonômica no GE (RMSSD 11,7 ± 4,2 vs 18,4 ± 5,7 p=0,02), LFnu (52,9 ± 17,2 vs 32,0 ± 18,2 p=0,02) e HFnu (48,1 ± 17,2 vs 68,0 ± 18,2 p=0,01). Não foram evidenciados efeitos adversos e não houve abandono do treinamento. Baseados nestes resultados, é possível concluir que o exercício aeróbio intradialítico por 12 semanas pode melhorar parâmetros cardiorrespiratórios, hemodinâmicos e autonômicos, com boa aderência e sem eventos adversos, podendo ser usado como medida coadjuvante para melhora clínica destes pacientes.

Chronic kidney disease (CKD) is a clinical condition of high cardiovascular risk and patients in the more advanced stages of the disease who depend on renal replacement therapy often experience cardiorespiratory impairment, high blood pressure levels (use of multiple medications for control), modulation impaired autonomy and varying degrees of inflammation. Thus, this study aims to verify whether intradialytic aerobic exercise has an impact on modifying these variables. The patients were selected in two hemodialysis units in São Luís do Maranhão, Brazil, between May 2016 and October 2019, and were allocated according to acceptance in the control group (CG) and exercise group (EG). The group exercise was submitted to aerobic exercise with bicycle for a period of 12 weeks. Anthropometric physical evaluation, 6-minute walk test (6MWT), echocardiogram, electrocardiogram with analysis of heart rate variability (VFC) and laboratory measurements were performed including interleukin 6 (IL6) before and after 12 weeks in both groups. Thirty-one patients were evaluated 15 patients in the control group (CG) and 16 patients in the exercise group (EG). After 12 weeks of training, there was a decrease in systolic blood pressure in the exercise group compared to baseline (129.8 ± 9.41 mmHg vs 112.00 ± 12.0 mmhg p = 0.03). There were no changes in body composition and in most laboratory tests, except for an increase in KTV (dialysis adequacy index) and a decrease in LDL cholesterol in the exercise group compared to the control group. However, HDL cholesterol levels increased (39.92 ± 6.1 mg / dL vs 48.00 ± 7.85 mg / dL p = 0.02) and IL6 decreased (4.56 ± 1.2 pg / mL vs 2.14 ± 1.0 pg / mL p = 0.02). There was an increase in the distance covered in the walking test in the exercise group (473.80 ± 98.6 m vs 573.50 ± 74.22 m p = 0,01). In the echocardiographic evaluation, it was found that in the EG there was a decrease in the estimated pulmonary artery pressure (31.38 ± 2.9 mmhg vs 24.2 ± 1.7 mmhg p = 0.001). There was an improvement in autonomic modulation in the EG (RMSSD 11.7 ± 4.2 vs 18.4 ± 5.7 p = 0.02), LFnu (52.9 ± 17.2 vs 32.0 ± 18.2 p = 0.02) and HFnu (48.1 ± 17.2 vs 68.0 ± 18.2 p = 0.01). There were no adverse effects and training was not abandoned. Based on these results, it is possible to conclude that intradialytic aerobic exercise for 12 weeks can improve cardiorespiratory, hemodynamic, and autonomic parameters, with good adherence and without adverse events, and can be used as a supporting measure for the clinical improvement of these patients.

Correlação entre a distância percorrida em testes de caminhada e o nível de atividade física de adultos e idosos assintomáticos / Correlation between the distance traveled on walking tests and the level of physical activity in asymptomatic middle-aged and older adults

Introdução: O incremental shuttle walk test (ISWT) pode estar mais bem correlacionado com o nível de atividade física diária (NAFVD) comparado ao teste de caminhada de 6 minutos (TC6). Objetivo: Avaliar as correlações entre o NAFVD e as distâncias percorridas no TC6 e ISWT. Métodos: Selecionamos 29 adultos e idosos assintomáticos por conveniência. Estatura e peso foram coletados para cálculo do IMC. Todos foram submetidos aos testes de caminhada duas vezes em dias alternados. Mensuramos a pressão arterial, frequência cardíaca, dispneia e fadiga de membros inferiores antes e após os testes. O NAFVD foi avaliado por meio de um acelerômetro uniaxial e pelo questionário de atividade física (IPAQ). Resultados: Após análise de regressão múltipla, apenas a distância do ISWT foi determinante para número de passos diários obtidos pela acelerometria, explicando 26% da variabilidade total dessa variável. Conclusão: O ISWT se mostrou válido para estimar o NAFVD de maneira mais adequada quando comparado ao TC6.

Introduction: The incremental shuttle walk test (ISWT) may be better correlated with the level of physical activity in daily life (NAFVD) compared to the 6-minute walk test (6MWT). Objective: To evaluate the correlations between the NAFVD and the distances covered in the 6MWT and ISWT. Methods: We selected 29 asymptomatic middle-aged and older adults for convenience. Height and weight were collected to calculate BMI. All were submitted to walking tests twice in alternate days. We measured blood pressure, heart rate, dyspnea, and leg fatigue before and at the end of the tests. NAFVD was evaluated using an accelerometer with a pedometer and the International Physical Activity Questionnaire (IPAQ). Results: After multiple regression analysis, only the ISWT distance was determinant for the number of daily steps obtained by the accelerometry, explaining 26% of the total variability of this variable. Conclusion: The ISWT proved valid to estimate NAFVD more adequately when compared to the 6MWT.

Sarcopenia, nutritional status and functionality in elderly women living in the community / Sarcopenia, funcionalidade e estado nutricional em idosas residentes na comunidade

Abstract Objective: to evaluate the relationship between sarcopenia, functional capacity and nutritional status among elderly women living in the community. Method: an observational, cross-sectional study was performed with 100 elderly women aged over 60 years. A questionnaire containing identification and socioeconomic data and information relating to the practice of physical activity was applied, while anthropometric and body composition data were measured through bioimpedance and functionality data was assessed using the six-minute walk test (6MWT). Independent t-tests were performed for the quantitative variables and analysis of variance (ANOVA) was used to compare the means of the variables. Multiple linear regression analyzes were performed to estimate the mean 6MWTfor each of the variables studied. Results: The average age of the elderly women was 67 (± 8.0) years, 41% practiced physical activity, 38% had at least an elementary school education, 48% received up to two minimum wages and 91% were obese according to waist circumference (WC). The prevalence rates for the presence of sarcopenia were: 5% for sarcopenic obesity (SO), 63% for obesity, 14% for sarcopenia and 18% had adequate weight. Elderly women who practiced physical activity, had at least an elementary education and who were non-obese according to WC, performed better in the 6MWT. There were no significant differences in the 6MWTbased on income or Body Mass Index (p>0.05). Non-obese and non-sarcopenic women walked further in the functional test than the other women (p = 0.021). Conclusion: SO was present in 5% of the elderly women and is related to poor physical performance, which was also present in elderly women with sarcopenia and obesity.

Resumo Objetivo: Avaliar a relação entre a sarcopenia, a capacidade funcional e o estado nutricional de idosas da comunidade. Método: Estudo observacional analítico, de caráter transversal, realizado com 100 idosas acima de 60 anos de idade. Para a coleta de dados, aplicou-se um questionário contendo informações de identificação, dados socioeconômicos, prática de atividade física, dados antropométricos e de composição corporal por meio da aplicação da bioimpedância e dados de funcionalidade por meio do teste de caminhada de seis minutos (TC6min). Realizaram-se testes t independente para variáveis quantitativas e análises de variância (ANOVA) para comparar as médias das variáveis. Foram realizadas análises de regressão linear múltipla para estimar as médias do TC6min para cada uma das variáveis estudadas. Resultados: A média de idade das idosas foi de 67 (±8,0) anos, 41% praticavam atividade física, 38% possuíam pelo menos o ensino fundamental, 48% recebiam até dois salários mínimos e 91% eram obesas de acordo com a circunferência da cintura (CC). As taxas de prevalência quanto à presença de sarcopenia foram: 5% para obesidade sarcopênica (OS), 63% obesidade, 14% sarcopenia e 18% adequado. Idosas que praticavam atividade física, que tinham pelo menos o ensino fundamental e não obesas, de acordo com a CC, tiveram melhor desempenho no TC6min. Não houve diferenças significativas no TC6min de acordo com a renda ou Índice de Massa Corporal (p>0,05). As idosas não obesas e não sarcopênicas caminharam mais no teste de funcionalidade que as demais (p=0,021). Conclusão: A OS foi presente em 5% das idosas e tem relação com pior desempenho físico, também presente em idosas com sarcopenia e obesidade.

Análise físico funcional e cardiorrespiratória de pacientes em lista de espera para o transplante renal: estudo transversal / Physical, functional, and cardiorespiratory analysis of patients on the kidney transplant waiting list: a cross-sectional study

Introdução: Para o tratamento da doença renal crônica os pacientes necessitam de hemodiálise ou diálise peritoneal enquanto aguardam em lista de espera pelo transplante renal. Apesar dos avanços nos procedimentos de diálise, os pacientes que fazem esse tratamento apresentam baixa capacidade física e funcional e comorbidades que influenciam no tempo de espera. Objetivo: Descrever as características físicas, antropométricas e cardiorrespiratórias de pacientes em lista de espera para o transplante renal, assim como, analisar as variáveis de acordo com o tempo em lista de espera e tempo de diagnóstico da doença. Materiais e métodos: Estudo transversal, descritivo e analítico, submetido e aprovado pelo Comitê de Ética em Pesquisa da UNIJUÍ parecer n° 1.992.013. Foram avaliados 11 pacientes cadastrados no Hospital de Caridade de Ijuí, quanto aos dados sobre a doença renal e seu tratamento, tempo em lista de espera, fatores de risco cardiovasculares, resistência muscular de membros inferiores, força muscular respiratória e capacidade funcional submáxima. Resultados: Foram avaliados 11 pacientes, sendo 54,5% do sexo feminino, média de idade de 51,9±11,4 anos, 45,5% tinham doença renal de origem hipertensiva, tempo de diagnóstico da doença de 84,0 (48,0-180,0) meses, 90,9% realizavam hemodiálise há uma mediana de 15,0 (8,0-41,0) meses e estavam em lista de espera há 12,0 (6,0-32,0) meses. Os fatores de risco cardiovasculares mais prevalentes foram hipertensão e sedentarismo. No teste de sentar e levantar em um minuto realizaram 17,0 (16,0-22,0) repetições, pressão inspiratória máxima de 62,0 (50,0-80,0) cmH2O, pressão expiratória máxima de 78,0 (64,0-99,0) cmH2O e percorreram 452,5 (416,1-503,2) metros no teste de caminhada em seis minutos. Conclusão: Os pacientes cadastrados em lista de espera para o transplante renal do nosso estudo apresentaram uma boa condição físico funcional e cardiorrespiratória. O tempo de diagnóstico da doença renal se correlacionou moderada e negativamente com a pressão expiratória máxima. O tempo de permanência em lista de espera não se correlacionou com a resistência de membros inferiores, força muscular respiratória e capacidade funcional submáxima. [AU]

Introduction: For the treatment of chronic kidney disease patients require hemodialysis or peritoneal dialysis while they wait for a kidney transplant waiting list. Despite advances in dialysis procedures, the patients who undergo this treatment have low physical condition and comorbidities that influence waiting time. Objective: To describe the physical characteristics, anthropometric and cardiorespiratory of patients on the waiting list for renal transplantation, as well as to analyze the variables according to waiting list time and disease diagnosis time. Materials and methods: A cross-sectional, descriptive and analytical study submitted and approved by the Research Ethics Committee of UNIJUÍ, report No. 1.992.013. Eleven patients registered at Ijuí Charity Hospital were evaluated for data on kidney disease and its treatment, waiting list time, cardiovascular risk factors, lower limb muscle resistance, muscle strength respiratory and submaximal functional capacity. Results: Eleven patients were evaluated: 54.5% female, average age 51.9 ± 11.4 years, 45.5% had hypertensive renal disease, diagnosis time of 84.0 (48.0-180.0) months, 90.9% underwent hemodialysis an average of 15.0 (8.0-41.0) months and were on the waiting list for 12.0 (6.0-32.0) months. The most prevalent cardiovascular risk factors were hypertension and sedentary lifestyle. In sit and stand up test in a minute performed 17.0 (16.0-22.0) repetitions, maximum inspiratory pressure 62.0 (50.0-80.0) cmH2O, maximum expiratory pressure 78.0 (64.0-99.0) cmH2O and walked 452.5 (416.1-503.2) meters in the walk test in six minutes. Conclusion: The patients registered on the waiting list in our study had a good physical functional and cardiorespiratory fitness. The time to diagnosis of renal disease was moderately and negatively correlated with maximal expiratory pressure. Waiting time did not correlate with lower limb muscle resistance, muscle strength respiratory and submaximal functional capacity. [AU]

HOSPITAL BASED 4 WEEK PHYSICAL THERAPY PROGRAM RESULTS AFTER ACUTE MYOCARDIAL INFARCTION / Шинэ санаа Шинэ нээлт

@#BACKGROUND: Early physical therapy plays important role in improving functional capacity, activities of daily life, and quality of life after acute myocardial infarction. OBJECTIVE: We aimed to describe effects of 4 weeks physical therapy program after acute myocardial infarction. METHODS: In our study, 20 men participated in physical therapy program for 14 days after PCI surgery. The patients were diagnosed with myocardial infarction and aged 56.45±8.1. Their BMI was 27.39±3.61and waist circumference was 98±9.28. Exercise program was scheduled 3 times a week with each session consisting of 34-70% intensity exercises for 60 minutes. Exercise type is aerobic (warming up for 10 minutes, walking, bicycling and cooling down stretch for 10 minutes). RESULTS: For the 6-minute walking test (p=0.01) there was significant difference between before and after 4 weeks’ exercise program. CONCLUSION: The hospital based 4 weeks exercise program improved the functional capacity for pci patients.

Application of handgrip strength test for evaluating mobility in patients with stable chronic obstructive pulmonary disease(COPD) / 中华护理杂志

Objective To explore the reliability of handgrip strength test for evaluating mobility in patients with stable chronic obstructive pulmonary disease.Methods Sixty-one COPD patients in stable stage were measured for handgrip strength and 6-minute walking test(6MWT).The receiver operating characteristic curve(ROC) was calculated to determine the best cutoff points of handgrip strength.Results Handgrip strength was (33.72-±7.47) kgf,6MWD was (437.06±97.96) m,handgrip strength was moderately correlated with 6MWD (r=0.404,P=0.001).6MWD≥350 m was used to classify two groups,and there was significant difference between two groups(P＜0.05).Area under the curv e was 0.722,and the best cutoff points was 32.8 kgf.Conclusion Handgrip strength test can be a useful tool to quickly identify mobility in patients with stable COPD.

Brain Cell Injuries and Behavioral Changes in Rats with Kernicterus / 中国康复理论与实践

@#Objective To study the brain cell injuries and behavioral changes of newborn rats with kernicterus. Methods Twenty-five 5-day-old Sprague-Dawley rats were divided into control group (n=11) and model group (n=14) radomly. The model group was injected with bilirubin solution 10 μg/g in the cisterna magna, while the control group was injected with equal volume of normal saline. The neurobehavioral changes were observed and the body mass were recorded. TUNEL staining was used to check the apoptosis of striatal nerve cells of basal ganglia in the model group (n=3) on the first day after modeling. The remaining rats were assessed by gait analysis and beam-walking test 19 days after birth, and Morris water maze test was performed 30 days after birth. Results The model group showed apparently abnormal neurobehavioral changes, such as clenched fists, opisthotonos and the body mass were significantly lower in the model group than in the control group (F>27.707, P<0.001). TUNEL staining showed striatal nerve cells apoptosis in the model group. For the gait analysis, the step lengths of both hind legs were shorter (t>4.129, P<0.01), and the difference of step length was longer (t=-4.415, P<0.001) in the model group than in the control group, however, there was no significantly difference in the step width between two groups (t=0.462, P=0.649). For the beam-walking test, the score was lower in the model group than in the control group (t=-3.644, P=0.004). For the Morris water maze test, the escape latency was longer (F>6.206, P<0.05), and the number of crossing platform was less (t=3.297, P=0.004) in the model group than in the control group. Conclusion The newborn rats' model of kernicterus showed deficits in multiple motor functions and learning and memory ability, which could be assessed by gait analysis, beam-walk test and Morris water maze test, respectively.

Efeitos de um programa de exercício físico em pacientes com doença arterial obstrutiva periférica / Effects of physical exercise program in patients with obstructive peripheral arterial disease

O objetivo do estudo foi estratificar os fatores de risco cardiovasculares (FR) e avaliar os efeitos de um programa de exercício físico (PEF) por três meses em pacientes diagnosticados com doença arterial obstrutiva periférica (DAOP) através do teste de caminhada de 6 minutos (TC6), utilizando como parâmetro a distância total percorrida (DTP), tempo inicial da dor (TID), tempo final da dor (TFD) e tempo total da dor (TTD). O estudo foi composto por 12 voluntários, encaminhados para o programa de Reabilitação Física. Para estratificar os FR houve aplicação de questionário contendo pergunta objetivas com opção de sim ou não sobre tabagismo, diabetes mellitus, etilismo, hipertensão arterial, sedentarismo, hereditariedade, dislipidemia e obesidade, adotou-se o índice de massa corpórea. O TC6 foi realizado em um corredor de 22 metros e o paciente foi orientado a informar aos avaliadores o momento de início da dor (TID) e somente parar quando a dor tornar-se insuportável para continuar a caminhada. O TFD foi estabelecido quando o paciente retornou ao TC6. Ao final do teste foi calculada a DTP que o paciente atingiu. O teste de ANOVA foi utilizado para comparar as condições pré e pós-reabilitação, tendo nível de significância quando p<0,05. Observou-se que todos os pacientes mostraram-se sedentários, 58,3% são dislipidêmicos, 50% são tabagistas, hipertensos e apresentam hereditariedade. Houve diferença significativa na DTP (327,7±83,3 vs 431,7±90,5), TID (01:52±0:36 vs 02:59±0:41) e TTD (01:55±0:14 vs 00:45±0:36) pré e pós-reabilitação. O PEF para pacientes com DAOP se mostrou eficaz na DTP, TID, TTD.

Assess the nutritional status of patients with chronic obstructive pulmonary disease by SGA / 天津医药

Objective To explore the subjective global assessment (SGA) to evaluate the nutritional status of patients with chronic obstructive pulmonary disease(COPD). Methods Patients with stable COPD (n=122) were included and divid?ed into three groups base on their SGA scores:SGA-A (n=21), SGA-B (n=57), SGA-C (n=44). Nutritional status of all pa?tients was assessed by SGA. Anthropometric measurement, biochemical test, pulmonary function test, COPD assessment test (CAT) and shuttle walking test (SWT) were studied between all three groups to search statistical significance and correlation with SGA. Results Body mass index(BMI), arm muscle circumference (AMC) and forced expiratory volume in the first sec?ond%of predicted (FEV1%Pred) were all lower in SGA-B and SGA-C than those in SGA-A(P<0.05),there were no statis?tical differences of these parameters between SGA-B and SGA-C. Triceps skin fold (TSF) was lower in SGA-C than that in SGA-B than that in SGA-A, while CAT score is the reverse order (P<0.05). The walking distance of incremental shuttle walking test (ISWI) and the endurance time of endurance shuttle walking test (ESWI) were lower in SGA-C than that in SGA-A (P<0.05). There were no statistical differences of forced expiratory volume in the first second (FEV1)/forced vital ca?pacity(FVC), biochemical parameters between all three groups. SGA scores correlated positively with CAT and negatively with anthropometric parameters, FEV1%Pred and SWT (P<0.05). However no correlations was deduced between SGA scores with FEV1/FVC and biochemical parameters. Conclusion SGA scores correlated with anthropometric parameters, FEV1%Pred, CAT and SWT. SGA is an effective method to assess the nutritional status in patients with stable COPD.

Tolerancia al ejercicio en pacientes posquirúrgicos cardiovasculares luego de la intervención con un programa de rehabilitación cardiaca fase II / Exercise tolerance in post-surgical cardiovascular patients after intervention with cardiac rehabilitation program phase II

Introducción y objetivos: La enfermedad cardiovascular constituye la primera causa de muerte y de gastos sanitarios debido a sus consecuencias. En prevención secundaria, los programas de rehabilitación cardiaca mejoran el estado funcional y la calidad de vida, e incrementan la supervivencia. Métodos y materiales: Estudio observacional, descriptivo y prospectivo, en el que se incluyeron 31 pacientes (19 hombres y 14 mujeres), con edad promedio de 64 ± 11 años. El test de caminata de 6 minutos sirvió para estimar el consumo de oxígeno máximo indirecto (VO2máx). Se midió la frecuencia cardiaca y se estimó el doble producto como indicadores hemodinámicos. Las pruebas se realizaron antes y después de 12 sesiones de entrenamiento entre el 50 y 70% de la frecuencia cardiaca máxima, 60 min, 3 veces por semana, durante un mes. Resultados: Luego de la intervención, se observaron mayores valores en el VO2 (9,6 ± 2 mL/kg-1/min-1 vs. 11,09 ± 1,9 mL/kg-1/min-1; p = 0,002) y en la distancia alcanzada en el test (244,5 ± 80,1 m vs. 303,2 ± 78,1 m; p = 0,002). No hubo diferencias en los indicadores hemodinámicos (p > 0,05). Conclusiones: El programa de rehabilitación cardiaca reportó una mejoría de tolerancia al ejercicio para los pacientes posquirúrgicos cardiovasculares en promedio del 14%, sin modificar la función hemodinámica.

Introduction and objectives:Cardiovascular disease is the leading cause of death and medical expenses due to its consequences. In secondary prevention, cardiac rehabilitation programs improve functional status, quality of life and overall survival. Methods and materials: An observational, descriptive and prospective study was performed. Thirty one subjects (19 male, 14 female), mean age 64 ± 11 years. The 6-minute walk test served to estimate the indirect maximal oxygen consumption (VO2max). We measured the heart rate and double product was estimated as hemodynamic indicators. The tests were performed before and after 12 training sessions at between 50 and 70% of maximum heart rate, for 60 min, 3 times a week, during one month. Results: After the intervention we observed higher values of VO2 (9.6 ± 2.0 mL.kg-1.min-1 vs. 11.09 ± 1.9 mL.kg-1.min-1; p = 0.002) and a longer distance achieved in the walking test (244.5 ± 80.1 m vs. 303.2 ± 78.1 m; P = .002). There were no differences in hemodynamic indicators (P > .05). Conclusions: Cardiac rehabilitation program reported an improvement in exercise tolerance in post-surgical cardiovascular patients in a 14% of the cases. It did not show a variation in hemodynamic function.

Test de caminata de seis minutos y función pulmonar en pacientes con bronquiolitis obliterante post infecciosa / Six minute walking test and pulmonary function in patients with post infectious bronchiolitis obliterans

Introduction: Post-infectious bronchiolitis obliterans (BO) is a chronic respiratory disease that is established as a consequence of a lung infection produced by adenovirus. The clinical and radiological evidence as well as spirometric variables are the cornerstones of diagnosis; however, the functional impact of lung damage, assessed through the six minute walking test (6MWT), has been scarcely studied in this group of patients, notwithstanding it has been recommended in the Chilean guidelines. The aim of the study is to evaluate the correlation between spirometric variables and 6MWT performance in patients diagnosed with BO. Patients and Methods: Correlation study conducted in pediatric pulmonary rehabilitation program of Guillermo Grant Benavente Hospital from Concepción. Chile. Records of spirometry (FEV1, FVC, FEV1/FVC and FEF25-75) and 6MWT(Distance walked (DW), heart rate, oxygen saturation, dyspnea and leg fatigue) of 22 children and adolescents diagnosed with BO were selected. The absolute values of spirometric and 6MWT variables were compared with reference values of Knudson et al and Gatica et al respectively. Results are expressed by median and range (maximum and minimum). In the statistical analysis, normality test (Kolmogorov-Smirnov), non-parametric test (Wilcoxon, Mann-Whitney) and correlation analysis (Rho-Spearman) were done by SPSS 11.5 with significance of p < 0.05. Results: The spirometry was obstructive in all patients, advanced ventilatory limitation was found in 9 children, moderate in 4, mild in 3 and minimum in 6. The WD was 597 m (750-398), 9% below the predicted value according to age (p < 0.003). The WD was lower in those with greater severity in spirometric impairment (p = 0.012). The WD expressed as a percentage of predicted value showed a significant correlation with % FEV1 (r = 0.70, p = 0.0001), FEV1/FVC ratio (r = 0.58, p = 0.004) and FEF25-75% (r = 0.70, p = 0.0001). On the other hand only saturation at the end of 6MWT showed significant correlation with % FVC (r = 0.44, p = 0.04). Conclusion: Performance during the 6MWT was positively correlated with spirometry, validating the 6MWT as a tool to assess the functional impact of lung damage in patients with BO. Future prospective studies are needed to evaluate the correlation between lung function and exercise tolerance in these patients.

Introducción: La bronquiolitis obliterante (BO) post infecciosa es una enfermedad respiratoria crónica que se establece como secuela de una infección pulmonar principalmente por adenovirus. La evidencia clínica, espirométrica y radiológica son los pilares del diagnóstico, sin embargo, pese a estar sugerido en las actuales guías nacionales, la repercusión funcional del daño pulmonar a través del test de caminata de seis minutos (C6M) ha sido escasamente estudiado en este grupo de pacientes. El objetivo de este estudio es evaluar la correlación entre variables espirométricas y resultado del C6M en una muestra de pacientes con BO. Pacientes y Métodos: Estudio correlacional donde fueron seleccionados los registros de espirometría (VEF1, CVF, VEF1/CVF y FEF25-75) y de C6M (Distancia caminada (DC), frecuencia cardíaca, saturación de oxígeno, disnea y fatiga de piernas) de 22 niños y adolescentes con diagnóstico de BO ingresados al programa de rehabilitación respiratoria infantil del Hospital Dr. Guillermo Grant Benavente de Concepción. Los valores absolutos de las variables espirométricas y C6M se compararon con valores predichos de Knudson y Gatica respectivamente. En el análisis estadístico se realizaron pruebas de normalidad (Kolmogorov-Smirnov), de contraste (Wilcoxon y Mann-Whitney) y análisis de correlación (Rho-Spearman). Los resultados se expresan en mediana, rango máximo y mínimo. Se consideró significativo p < 0,05. Resultados: En la espirometría se encontró alteración ventilatoria obstructiva de grado avanzado en 9, moderada en 4, leve en 6 y mínima en 3 niños. La DC fue de 597 m (750-398), 9% por debajo del valor predicho para la edad (p < 0,003). La DC fue menor en aquellos con mayor grado severidad en la alteración espirométrica (p = 0,012). La DC expresada en porcentaje del valor predicho mostró una correlación significativa con % VEF1 (r = 0,70;p = 0,0001), índice VEF1/CVF (r = 0,58;p = 0,004) y % FEF25-75 (r = 0,70;p = 0,0001). Sólo la saturación al final del C6M se correlacionó significativamente con % CVF (r = 0,44; p = 0,04). Conclusión: El rendimiento durante el C6Mse correlacionó con espirometría, validando al C6M como herramienta para valorar la repercusión funcional del daño pulmonar en pacientes con BO. Futuros estudios son necesarios para confirmar esta correlación.

Quantification of Vestibulospinal Reflex Under the Stress Condition on Both Soleus Muscles / 대한평형의학회지

BACKGROUND AND OBJECTIVES: Vestibulospinal reflex (VSR), which is measured in static state, tends to be compensated prior to vestibule-ocular reflex. Therefore, by establishing method that enables to track and observe quantified VSR, the reliability of experiment is attempted to be increased. MATERIALS AND METHODS: On five SD Rats to measure electromyogram (EMG), electrodes, in the form of stranded cables composed of seven wires, are chronically implanted on both sides of the soleus muscles. Pre and post operative condition of sitting still, standing, and ladder step walking was compared before, and six and twenty four hours after a unilateral labyrinthectomy with quantified muscle activity in maximal voluntary activity. Simultaneously by using multi modality electric potential plus package, the muscle activity between the two legs was tracked and compared. RESULTS: In the sitting still position, the left/right soleus muscle activities were 25.7/26.0 microV before a unilateral labyrinthectomy which was changed after the surgery with the value of 23.1/8.1 microV and 23.4/14.3 microV when six and twenty four hours passed respectively. In the standing position, 92.8/124.0 microV of preoperative value was changed to 89.6/37.3 microV six hours after the unilateral labyrinthectomy, and it was 97.0/54.7 microV 24 hours after. The preoperative value in ladder step walking test was 56.2/86.0 microV, and postoperative ones were 54.9/21.2 microV and 55.7/38.0 microV after six and twenty four hours respectively. CONCLUSION: VSR assessment method by using quantitative EMG well reflects the process of vestibular compensation, and to maintain the tension of extensor muscles, ladder step walking test is shown to be useful.

Teste de caminhada de seis minutos para avaliação de mulheres com fatores de risco cardiovascular / Six minute walk test on cardiovascular risk factors women evaluation

INTRODUÇÃO: A atividade física é uma das formas de prevenção ao aparecimento de fatores de risco cardiovascular, como a hipertensão arterial sistêmica (HAS) e o diabetes mellitus (DM). Uma das formas de avaliar é o teste de caminhada de seis minutos (TC6), que é um teste submáximo, simples de ser realizado, de baixo custo e alta reprodutibilidade. OBJETIVOS: Comparar o desempenho funcional de mulheres portadoras de risco cardiovascular, por meio do TC6. MÉTODOS: 45 mulheres foram alocadas em três grupos: G1 (com diagnóstico de HAS DM), G2 (diagnóstico de HAS) e G3 (voluntárias saudáveis). Inicialmente, as voluntárias realizaram o TC6 com caráter de aprendizado e uma hora depois o teste com caráter avaliativo. Considerou-se como variáveis pré e pós-teste a saturação periférica de oxigênio, a frequência cardíaca, a pressão arterial, a glicose e a distância percorrida. A análise estatística foi realizada com significância estipulada de p < 0,05. RESULTADOS: Todos os grupos aumentaram significativamente a distância percorrida no teste avaliativo, e tiveram acréscimo na pressão arterial e redução do índice glicêmico. CONSIDERAÇÕES FINAIS: O TC6 pode ser utilizado para avaliação da capacidade funcional de mulheres portadoras de HAS e DM como fatores de risco cardiovascular, demonstrando-se seguro e submáximo.

INTRODUCTION: The practice of physical activities is one of the options used for cardiovascular risks prevention, such as systemic arterial hypertension (SAH) and diabetes mellitus (DM). One of the ways to make an evaluation of it is the 6-minute-walk test (6MWT), which is a submaximal test, simple to be done, of low cost and high productive. OBJECTIVES: To compare the functional acting of women's organism with cardiovascular risk, through the 6MWT. METHODS: 45 women were allocated in 3 groups: G1 (with SAH DM diagnostic), G2 (SAH diagnostic) and G3 (healthy volunteers). Initially the volunteers made the 6MWT for learning and one hour later for evaluation. Saturation of peripheral oxygen, cardiac frequency, arterial blood pressure, glucose and distance made were considered as pre- and post-tests. The statistic analysis was made with stipulated relevance of p < 0,05. RESULTS: All groups that increased the distance made during the evaluation test, had higher blood pressure and reduction of the glucose indication. CONCLUSIONS: 6MWT can be used for evaluation of the functional acting of women's organism with SAH and DM as cardiovascular risk factors, being safe and submaximal.

La ventilación no invasiva mejora los resultados en las pruebas de ejercicio en pacientes con enfermedad pulmonar obstructiva crónica / Non-invasive ventilation improves the outcome of exercise in COPD patients

Existen pocos estudios sobre el efecto de la Ventilación de doble nivel de presión positiva (VNI) sobre el ejercicio en pacientes con EPOC. El objetivo fue evaluar el impacto de la VNI en la respuesta a ejercicios máximos ysubmáximos en pruebas de campo en pacientes con EPOC. Fueron incluidos pacientes con EPOC (definición GOLD). Se les realizó una prueba de 6 minutos (según normativas de ATS), de escalera (Girish et al., Chest 2001) y ShuttleTest (Singh et al., Thorax 1992) con medición de escala de Borg de miembros inferiores y disnea, saturación arterial y frecuencia cardíaca. A través de una máscara nasal, se adaptó VNI con promedio 15 cmH2O de IPAP y 4 cmH2O de EPAP, y luego se realizaronlas mismas pruebas de ejercicio. Fueron evaluados 11 pacientes con EPOC: mediana edad: 61 años (IC25-75%, 58-75), sexo masculino 72%, FVC: 65% (IC25-75%, 60,1-70); FEV1: 37,4(IC25-75%, 33,97-42,5); FEV1/FVC: 46 (IC25-75%, 42,5-52,5); PaO2:68 mmHg (IC25-75%,63-75,3); PaCO2:40mmHg (IC25-75%,39-41).En la prueba de 6 minutos, se observó que la VNI aumentaba la distancia caminada en 61.78 % (p=0.001) la distancia caminada y la carga (kg.m) en 16,55% (p=0.002). No había cambios significativos en los síntomas (fatiga y disnea) por escala de Borg. En la prueba de escalera, se observó que la VNI incrementaba la velocidad de ascensoen 11,81% (p=0.05), sin cambios significativos en los síntomas o la altura ascendida. En el shuttle test, se observó que la VNI aumenta la distancia caminada en 30.6% (p=0.001), sin cambio significativos en los síntomas.En conclusión, se observó una significativa mejoría en las distancias caminadas y mayor velocidad de ascenso en la de escalera. Es la primera comunicación del efecto de la VNIsobre pruebas de escalera en pacientes con EPOC.

There are few exercise studies about the effect of bi-level non-invasive ventilation (NIV) on the exercise in COPD patients. The objective of the study was to evaluate the impact of NIV on the results of submaximal and maximal field exercise tests in COPD patients. The COPD patients were selected according to the GOLD definition. The study tests included: the six minute walking test (ATS guidelines), stair climbing test (Girish et al., Chest 2001) and shuttle test (Singh et al., Thorax 1992) which were measured with the Borg scale for legs and dyspnea, arterial saturation and heart rate. With a nasal mask, the NIV was adapted with pressure support ventilation through 15 cm H2O of IPAP and 4 cm H2O of EPAP. Then, the same exercise tests were performed. Eleven COPD patients were evaluated: age (median) 61 years (IC25-75%, 58-75), male sex 72%, FVC: 65% (IC25-75%, 60.1-70); FEV1: 37.4(IC25-75%, 33.97-42.5); FEV1/FVC: 46 (IC25-75%, 42.5-52.5); PaO2: 68 mmHg (IC25-75%,63-75.3); PaCO2: 40mmHg(IC25-75%, 39-41). The NIV increased the walked distance by 61.78% (p=0.001) and load (kg.m) by 16.55%(p=0.002) in the six minute walking test. There was no significant difference in the symptoms (dyspnea and fatigue) in the Borg scale. The NIV increased the ascent velocity by 11.81% (p=0.05) in the stair climbing test. No significant changes in symptoms and ascended height were observed. The NIV increased the walked distance by 30.6% (p=0.001), without significant changes in symptoms. As conclusion, distance increased significantly with NIV in the six minute walking test and shuttle test. A higher velocity was observed in the stair climbing test. This study was the first experience of NIV on the stair climbing test in COPD patients.

Healthy adults maximum oxygen uptake prediction from a six minute walking test.

Background: A parameter is needed in medical activities or services to determine functional capacity. This study is aimed to produce functional capacity parameter for Indonesian adult as maximum O2. Methods: This study used 123 Indonesian healthy adult subjects (58 males and 65 females) with a sedentary lifestyle, using a cross-sectional method. Results: Designed by using the followings: distance, body height, body weight, sex, age, maximum heart rate of six minute walking test and lung capacity (FEV and FVC), the study revealed a good correlation (except body weight) with maximum O2. Three new formulas were proposed, which consisted of eight, six, and five variable respectively. Test of the new formula gave result of maximum O2 that is relevant to the golden standard maximum O2 using Cosmed® C-Pex. Conclusion: The Nury formula is the appropriate predictor of maximum oxygen uptake for healthy Indonesians adult as it is designed using Indonesian subjects (Mongoloid) compared to the Cahalin’s formula (Caucasian). The Nury formula which consists of five variables is more applicable because it does not require any measurement tools neither specific competency.

The effect of transcranial electrical stimulation on functional recovery and the expression of microtubule-associated protein-2 and growth-associated protein-43 after cerebral focal ischemia / 中华物理医学与康复杂志

Objective To assess the influence of transcranial electric stimulation (TES) on the recovery of motor function after cerebral focal ischemia and reperfusion and to explore the mechanisms in terms of neural plasticity.Methods An acute focal ischemia-reperfusion model was established by transient occlusion of the right middle cerebral artery (MCAO).Seventy-two male Sprague-Dawley rats were randomly divided into a TES group,a model group,a sham-operation group and a normal group.The TES group was given TES 24 h after MCAO;the model group received the operation without any treatment.Forelimb placing (FPT) and beam walking (BWT) were mea-sured at the 3rd,7th,14th and 28th day after reperfusion.Microtubule-associated protein-2 (MAP-2) and growth-associated protein-43 (GAP-43) and grey levels of reaction products in the peri-infarct region were examined by immunohistochemical techniques.Results The TES group rats had markedly better FPT and BWT performance at the 7th,14th and 28th day after MCAO,compared with the model group.Expression of MAP-2 had increased significantly more at the 14th and 28th day in the peri-infarct region in the TES group compared with the model group.Expression of GAP-43 was significantly elevated in the peri-infarct region in the TES group compared with the model group at all time points.Conclusions TES can improve motor function and neural plasticity following cerebral ischemia and reperfusion damage.The functional enhancement may be partly due to up-regulation of the expression of GAP-43 and MAP-2 in the peri-infarct region.

Influência da adiposidade corporal sobre a aptidão cardiorrespiratória em mulheres idosas / Influence of body adiposity on cardiopulmonary fitness in older women

Alterações fisiológicas são observadas no avançar da idade. Junto a estas modificações, a inatividade física passa ser considerada como um agravante no surgimento de doenças e no acúmulo deadiposidade corporal. O acúmulo de gordura pode ser determinante no rendimento motor. A partir disso, o objetivo do presente estudo foi observar a influência da adiposidade corporal na aptidão cardiorrespiratória em indivíduos idosos do sexo feminino. A amostra foi composta por 256 mulheres, participantes de programas de exercícios físicos, com idade entre 60,0 e 69,8 (64,3 ±2,84), residentes das cidades de Presidente Prudente-SP e Uberaba-MG –Brasil. Foram mensurados os valores de Índice de Massa Corporal (IMC), Razão Cintura e Quadril (RCQ), Índice de Conicidade (IC) e da Razão entre Cintura/Estatura (RCEst). A obtenção dos valores de Aptidão Cardiorrespiratória (AC) foi realizada por meio do Teste de Caminhada de Seis Minutos (TC6M). A análise estatística foi obtida após o agrupamento das variáveis a partir do percentil 50. A razão de chance foi obtida pelo testes exato de ”Ficher”, com o software R. A associação entre as variáveis foi calculada com o teste do Qui-quadrado, com Software SPSS 10.0. Todos os valores estatísticos foram estabelecidos com índice de significância de p=0,005. Foi observado que, o grupo de mulheres classificadas como baixo desempenho, apresentaram em média 2.0 vezes mais chances de possuir maiores valores de indicadores antropométricos. Desta forma, é possível concluir que a AC é negativamente influenciada pela adiposidade corporal.

Physiological changes are observed when people get old. With it, physical inactivity is considered an aggravating on emergence diseases and body adiposity’s accumulation. Fat’s accumulation can be determinant on motor performance. Then, the objective of the present study was observed bodyadiposity’s influence on cardiorespiratory fitness in female old individuals. The sample was composed by 256 women, physical exercises programs’ participants, age between 60,0 and 69,8 (64,3 ±2,84), lived inPresidente Prudente-SP and Uberaba-MG –Brazil’s cities. Were measured values about Body Mass Index (BMI), And waist: hip ratio (WHR), Conicity index (CI) and Ratio of waist/height (WHeR). Cardiorespiratory fitness (AC)’s results were realized by Test six-minute walk (6MWT). Statisticalanalysis were obtained after variables’ grouping from 50 percent. Chance’s rate was getting by ”Ficher” exact test, with software R. The association among variables was calculated with Qui-quadrado’s test, with Software SPSS 10.0. All the statistical values were established with significance index of p=0,005. Was observed that, women group classified as low performance, were average 2.0 times more chances ofhighest anthropometric rates values. This way, is possible to conclude that the AC is negatively influenced by body adiposity.