ABSTRACT
PURPOSE: To evaluate the effectiveness of wave-front-guided LASIK in reducing the increase of high order aberration, we compared the aberrational change and other clinical outcomes after LASIK by the conventional method and those by wave-front guided ablation. METHODS: 50 eyes of 25 patients were included. In one eye, conventional LASIK was performed (group1), then in the other eye, wave-front guided LASIK was performed (group2). Patient's optical aberrations were measured with Zywave(R) (Bausch and Lomb Surgical), Shack-Hartmann type of aberrometer. We then compared high order aberrations, contrast sensitivity, visual acuity, topographic result, and manifest refraction, preoperatively and postoperatively after 1 and 3 months. RESULTS: Uncorrected visual acuity improved to more than 20/20 in 2 eyes of group 1 and in 5 eyes of group 2. In group 1, RMS(H) were 0.235 preoperatively and 0.594 and 0.429 postoperatively after 1 and 3 month. In group 2, RMS(H) were 0.285, 0.442 and 0.353.Contrast sensitivity in the mesopic condition of the wave-front guided LASIK group was higher than that of the conventional ablation group. But this change was not statistically significant. CONCLUSIONS: The wave-front guided wave-front guided LASIK showed slightly better outcome than that of the conventional ablation in postoperative visual acuity, and contrast sensitivity in mesopic condition.