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0.05).Conclusion The rat model of liver-Qi stagnation can be induced by chronic stress,which is different from the syndromes of deficiency of both heart and spleen and the interior disturbance of phlegm-heat.
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[Objective] To observe the effect of spleen-stomach regulating herbal medicine in improving the nutritional status in dystrophic patients receiving maintenance hemodialysis. [ Methods ] Sixty-one dystrophic cases receiving maintenance hemodialysis were randomized into two groups. Group A ( n = 31) and group B ( n = 30) received the same symptomatic treatment and the same maintenance hemodialysis, and group A received spleen-stomach regulating herbal medicine additionally. For those in group A with spleen-stomach deficiency, Liujunzi Decoction was applied; for those with stagnation of phlegm, modified Huanglian Wendan Decoction was used. After treatment, the main symptoms and signs of dystrophy, triceps skin fold (TSF), and middle-arm muscle circumference (MAMC) were observed, as well as serum levels of total protein (TP), albumins (Alb) and transferrin (TRF), hemoglobin (HB), protein catabolic rate (nPCR) and SGA scoring for comprehensively nutritional evaluation. [Results] Compared with group B, symptoms and signs were much improved ( P
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Objective:To probe the therapeutic effect and adverse reaction of Wendan Decoction in combination with Clozapine for treatment of schizophrenia.Methods:Three groups were set up in the study,30 cases in each.The group Ⅰ were treated with Wendan Decoction,group Ⅱ with Wendan decoction plus Clozapine,and the control group with Clozapine.Positive and negative symptom scale(PANSS)and treatment emergent symptom scale(TESS)were used for evaluation of the therapeutic effect and adverse reaction.Results:The markedly effective rate was 70% and the effective rate was 30% in group Ⅱ,36.6% and 50% in the group Ⅰ,and 43.6% and 56.4% in the control group respectively.The adverse reactions in group Ⅰ and group Ⅱ were less than those in the control group.Conclusion:Wendan Decoction has a definite therapeutic effect on schizophrenia and the combined treatment has better therapeutic effect with high safety.It can improve symptoms and reduce the dosage of antipsychotics and the incidence of EPS.