ABSTRACT
Female adnexal tumors of probable Wolffian origin (FATWO) are rare. Although the histological features of the benign tumors are recognized, features of malignancy are not well defined in published work because these tumors are particularly rare. In this study, we report a 52-year-old woman with a High malignant FATWO. The frozen biopsy of the fragile uterine mass, located at the left broad ligament, revealed a malignant FATWO with high mitotic figure (up to 36/10 HPF). The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, omentectomy, and paraaortic and pelvic lymph node dissection. Pathologic findings were consistent with malignant FATWO infiltrating to the unilateral salpinx without lymph node metastasis. The patient received three cycles of adjuvant treatment with paclitaxel and carboplatin. There was no clinical evidence of recurrence during the 12 months of follow-up; the patient is currently still being followed-up.
Subject(s)
Female , Humans , Middle Aged , Adenoma , Adnexal Diseases , Biopsy , Broad Ligament , Carboplatin , Fallopian Tubes , Hysterectomy , Lymph Node Excision , Lymph Nodes , Neoplasm Metastasis , Paclitaxel , RecurrenceABSTRACT
A female adnexal tumor of probable Wolffian origin (FATPWO) is a rare neoplasm believed to originate from Wolffian remnants because the tumors are located in areas where such remnants are abundant. Because FATPWO is so rare that tumor biological behavior is not well defined, especially in cases of ovarian tumors, the collection and investigation of all relevant data, including this case report, are thus crucial to identify the best possible treatment for this type of tumor. We report a 14-year-old girl presented with a huge ovarian tumor that is reminiscent of dysgerminoma on CT scan. Left salpingo-oophorectomy was perfomed. Because the pathologic report on frozen section was malignant neoplasm, additional surgical staging was performed. A ovarian tumor of probable Wolffian origin was diagnosed by the pathologist, finally. No adjuvant therapy was given and there was no clinical evidence of recurrence during the 19 months of follow-up.
Subject(s)
Adolescent , Female , Humans , Dysgerminoma , Follow-Up Studies , Frozen Sections , Recurrence , Tomography, X-Ray ComputedABSTRACT
Female adnexal tumors of probable Wolffian origin (FATPWO) were first reported in 1973 and the disease is a rare clinical entity. They are often found in the leaves of the broad ligament, ovary and paravaginal tissue. We report a 40-year-old woman who presented with both adnexal masses filling the pelvic cavity which were hard and fixed on palpation, and the masses were radiologically diagnosed as both ovarian fibroma-thecomas on the CT scan. The left adnexal mass was surgically excised and pathologically proved to be fibroma, the left adnexal mass was excised and pathologically proved to be FATPWO.
Subject(s)
Adult , Female , Humans , Broad Ligament , Fibroma , Ovary , Palpation , Tomography, X-Ray ComputedABSTRACT
We report a case of right broad ligament tumor with features of female adnexal tumor of probable wolffian origin. A 40-year-old woman presented with dysfunctional uterine bleeding. Ultrasonography revealed 1 10cm sized right parovarian solid mass. On microscopic examination, the tumor showed mixed pattern of tightly packed tubular structures and diffuse spindle cell proliferation. Immunohistochemical study demonstrated cytokeratin-and vimentin-positivity and carcino-embryonic antigen-negativity. The ultrastructural study showed prominent tubular structures, continuous basal lamina, definite junctional complex but no secretory granules or glycogen particles, favoring wolffian origin.