Parental presence during invasive pediatric procedures: what does it depend on? / A presença dos pais durante procedimentos pediátricos invasivos: depende de quê? / Presencia de los padres durante procedimientos pediátricos invasivos: ¿De qué depende?

Abstract Objective: family-centered care during invasive procedures has been endorsed by many professional health care organizations. The aim of this study was to evaluate the health professionals' attitudes towards parental presence during their child's invasive procedure. Method: pediatric healthcare providers (divided in professional categories and range of ages) from one of the Spain's largest hospitals were asked to complete a questionnaire and write free-text comments. Results: 227 responded the survey. Most (72%) participants, in their answers, reported that parents are sometimes present during interventions, although there were differences between professional categories in this respect. The procedures in which the parents were present were those considered "less invasive" (96% of cases), while only 4% were present in those considered "more invasive". The older the professional, the less necessary parental presence was considered. Conclusion: the attitudes towards parental presence during pediatric invasive procedure are influenced by the professional category, the age of the healthcare provider and the invasiveness of the procedure.

Resumo Objetivo: o atendimento centrado na família durante procedimentos invasivos tem sido endossado por muitas organizações profissionais de saúde. O objetivo deste estudo foi avaliar as atitudes dos profissionais de saúde em relação à presença dos pais durante o procedimento invasivo realizado em seus filhos. Método: os prestadores de serviços de saúde pediátricos (divididos em categorias profissionais e faixa etária) de um dos maiores hospitais da Espanha foram solicitados a preencher um questionário e escrever comentários de texto livre. Resultados: a pesquisa foi respondida por 227 pessoas. A maioria (72%) dos participantes, em suas respostas, relatou que os pais algumas vezes estão presentes durante as intervenções, embora houvesse diferenças entre as categorias profissionais a esse respeito. Os procedimentos em que os pais estavam presentes eram aqueles considerados "menos invasivos" (96% dos casos), enquanto apenas 4% estavam presentes naqueles considerados "mais invasivos". Quanto mais velho o profissional, a presença dos pais foi considerada menos necessária. Conclusão: as atitudes em relação à presença dos pais durante o procedimento pediátrico invasivo são influenciadas pela categoria profissional, a idade do prestador de serviço de saúde e a invasividade do procedimento.

Resumen Objetivo: la atención centrada en la familia durante procedimientos invasivos ha sido respaldada por muchas organizaciones profesionales dedicadas al cuidado de la salud. El objetivo de este estudio fue evaluar las actitudes de los profesionales de la salud con respecto a la presencia de los padres durante los procedimientos invasivos realizados en niños. Método: a los prestadores de atención médica en Pediatría (divididos en categorías profesionales y rangos de edad) de uno de los hospitales más importantes de España se les solicitó que respondieran un cuestionario y redactaran comentarios de texto libre. Resultados: un total de 227 profesionales respondieron la encuesta. En sus respuestas, la mayoría (72%) de los participantes informó que, en ocasiones, los padres están presentes durante las intervenciones, aunque se registraron diferencias entre las distintas categorías profesionales al respecto. Los procedimientos en los que los padres estuvieron presentes se consideraron como "menos invasivos" (96% de los casos), mientras que solamente el 4% estuvo presente en los considerados "más invasivos". A mayor edad de los profesionales, menos necesaria se consideró la presencia de los padres. Conclusión: las actitudes con respecto a la presencia de los padres durante procedimientos pediátricos invasivos se vieron influenciadas por la categoría profesional, la edad del prestador de salud y la invasividad de los procedimientos.

Aportes del psicoanálisis a los estudios de abuso sexual infantil: Análisis del discurso de la madre de una niña abusada sexualmente / Contributions of psychoanalysis to studies of child sexual abuse: Mother's speech analysis about her sexually abused daughter

Se presentan los resultados dela tesis doctoral sobre los deseos y defensas (y sus estados) de la madre de una niña abusada sexualmente, con el objetivo de conocer su estructuración subjetiva en este difícil acontecimiento. Se trata de un estudio de caso en el que se usa como método el Algoritmo David Liberman (ADL), en el análisis del discurso de la madre, seleccionadas tres sesiones y una carta manuscrita. El estudio de deseos y defensas puede contribuir a describir y conocer el posicionamiento subjetivo de una madre frente a la situación abusiva de su hija, y como ésta es vivida por ella AU

The results of the doctoral thesis on the wishes and defenses (and their states) of the mother of a sexually abused girl are presented, with the aim of knowing her subjective structuring in this difficult event. This is a case study in which the David Liberman Algorithm (ADL) is used as a method in the analysis of the mother's speech, three sessions and a handwritten letter selected. The study of desires and defenses can contribute to describing and knowing the subjective position of a mother in the face of her daughter's abusive situation, and how it is experienced by her AU

Perfil de consumidores e sua percepção sobre antepasto de grão de bico contendo bactéria probiótica / Consumer profile and their perception of chickpea antipasto containing probiotic bacteria

Introdução: A indústria de alimentos e os pesquisadores têm-se dedicado a desenvolver novos produtos funcionais, com características mais naturais. Assim, estudos que identifiquem a demanda dos consumidores buscando atender seus anseios são importantes. Objetivo: Avaliar o perfil e a percepção de consumidores sobre antepastos, probióticos e a intenção de compras de um antepasto de grão de bico adicionado de bactéria probiótica. Método: A avaliação foi realizada de forma on-line, por meio de questionário contendo 33 questões respondidas por 322 participantes. Nuvens de palavras foram elaboradas com os resultados obtidos. Resultados: A maioria dos participantes reside na Região Sudeste, 72,7% são do gênero feminino, 37,3% possuem renda familiar de até três salários mínimos, 75,8% sabem o que é antepasto e mais da metade já consumiu grão de bico e conhece seus benefícios. Mais de 84,0% dos participantes sabem o que são probióticos e 90,1% já consumiram produtos probióticos de base láctea. Entretanto, 78,0% demonstraram interesse por opções de produtos probióticos de origem vegetal. Sobre as características que os participantes consideram que melhor descrevem o antepasto, as mais citadas foram: pastoso, macio, agridoce, salgado e firme. A nuvem de palavras mostrou que os respondentes associam probióticos à saúde intestinal e 36% deles estariam dispostos a comprar antepasto de grão de bico contendo probiótico se o produto estivesse disponível no mercado. Conclusão: O estudo indica que os consumidores têm interesse por grão de bico e probióticos, havendo uma demanda potencial por alimentos de origem vegetal contendo probióticos.

Introduction: The food industry and researchers have been dedicated to developing new functional products with more natural characteristics. Thus, studies that identify the demand of consumers seeking to meet their desires are important. Objective: To evaluate the profile and perception of consumers about antipasti, probiotics and purchase intention of a chickpea antipasti added with probiotic bacteria. Method: The evaluation was carried out online, through a questionnaire sent to 322 participants, containing 33 questions. Word clouds were created with the results obtained. Results: Most participants live in the Southeast region, 72.7% are female, 37.3% have a family income of up to three minimum wages, 75.8% know what antipasto is and more than half have consumed beak and knows its benefits. More than 84.0% of the participants know what probiotics are and 90.1% have already consumed dairy-based probiotic products. However, 78.0% showed interest in options for probiotic products of plant origin. About the characteristics that the participants consider that best describe the antipasto, the most cited were: Pasty, Soft, Bittersweet, Salty and Firm. The word cloud showed that respondents associate probiotics with gut health and 36% of those would be willing to buy probiotic-containing chickpea antipasto if the product were available on the market. Conclusion: The study indicates that consumers are interested in chickpeas and probiotics, with a potential demand for plant-based foods containing probiotics.

Co-word Analysis of the Current Situation of Narrative Medicine Research in China in the Past Decade / 中国医学伦理学

【Objective:】 The co-word analysis method was used to analyze narrative medical literature studied in China in the past 10 years to explore the research status in this field and lay a foundation for further research. 【Methods:】 Using "narrative medicine" as the theme term, with the limited time interval of 2013—2022 to retrieve for relevant literature in CNKI, Wanfang, and VIP databases, and include literature that meets the research standards. Bicomb2 was used to perform keyword statistics and analysis on the downloaded literature. Ucinet6.0 and Netdraw were used to draw co-occurrence analysis graphs to visualize the co-occurrence relationship between high-frequency keywords. 【Results:】 A total of 565 papers were included and 31 high-frequency keywords were extracted. The co-occurrence relationship diagrams showed that the current research hotspots of narrative medicine in China include traditional Chinese medicine, nursing, general practice, evidence-based medicine, medical ethics, hospice care, chronic diseases, cancer and other popular disciplines and diseases. Most of them were about enhancing the empathy and humanistic caring ability of medical personnel and improving doctor-patient communication to improve the doctor-patient relationship, as well as doing well in medical humanities education and cultivating narrative ability through parallel medical records and reflective writing. The research on gerontology, improving the professional identity of medical staff, integrating literature and medicine, and the impact on patients were relatively few. 【Conclusion:】 At present, narrative medicine in China has achieved many achievements in fields such as nursing, traditional Chinese medicine, general practice medicine, chronic diseases, cancer, medical humanities education, and improving doctor-patient relationships. In the future, in-depth exploration can be conducted from the use of narrative medicine in multi-disciplinary and disease fields, trying different training methods, and synchronous cultivation of teachers and students, so as to build a more comprehensive narrative medicine system.

Research Status and Suggestion of Drug Clinical Trial Risk Management in China: Based on Co-word Analysis and Social Network Analysis Perspective / 中国医学伦理学

【Objective:】 To deeply understand the current situation and hotspots of drug clinical trials risk management in China. 【Methods:】 Co-word analysis and social network analysis were used to sort out the study results of risk management in drug clinical trials in China. 【Results:】 The trend of risk research of drug clinical trials in China was generally on the rise. The research hotspots focused on four areas: drug supervision and pharmacovigilance, risk management of drug clinical trial institutions, ethical review of drug clinical trials, and risk management of drug clinical trials. 【Conclusion:】 In the future, China should gradually improve the risk management system and supervision system of drug clinical trials, explore to establish a risk-based quality management and ethical review system of drug clinical trials, and enhance the risk assessment and coping ability of institutions.

Research on the motivation of young patients′ medical electronic word-of-mouth sharing on internet platforms / 中华医院管理杂志

Objective:To explore the facilitating and inhibitory factors influencing the behavior of young patients to share medical electronic word-of-mouth (eWOM) on internet platforms, so as to provide insights for the improvement of healthcare quality.Methods:In May 2022, 271 undergraduate students from universities in Zhejiang province were selected by convenient sampling to survey their motivations to share eWOM with a self-designed questionnaire. Multiple regression analysis was used to examine the impact of different motivational factors on the sharing intention of young patients.Results:Only 16 respondents (5.9%) had previously published medical eWOM. Egoistic motivation, altruistic motivation, medical experience, and comment habits were significant factors that promoted patients to share eWOM, with egoistic motivation ( β=0.212, P<0.001) having the greatest impact and comment habit ( β=0.139, P=0.003) having the least impact. Distrust, low self-efficacy and involvement, perceived reluctance, and perceived uselessness were significant factors inhibiting patients from publishing eWOM. Of them, distrust ( β=-0.161, P<0.001) and perceived reluctance ( β=-0.161, P=0.001) had the greatest impact, and low self-efficacy and involvement had the least impact ( β=-0.134, P=0.003). Conclusions:To enhance the positive attitude of young patients towards sharing eWOM, it is important to focus on their personal benefits and provide high-quality healthcare experiences. Building trust among patients in the platform is crucial, and efforts should be made to reduce operational barriers. Additionally, educating and raising awareness among young patients regarding the significance and influence of healthcare reviews is important.

Análisis de perfil temático sobre la COVID-19 en revistas médicas cubanas durante los primeros 90 días de la pandemia

La evaluación de la producción científica ha sido de vital importancia para el desarrollo adecuado de políticas científicas. En el escenario actual, mediado por la pandemia y la infoxicación, es trascendental el empleo de los métodos bibliométricos para conocer el desarrollo de las publicaciones científicas sobre la COVID-19. El objetivo fue analizar el perfil temático de la producción científica sobre la COVID-19, publicada en las revistas médicas cubanas durante los primeros 90 días de la pandemia. Se realizó un estudio bibliométrico, con diseño no experimental y enfoque cuantitativo de alcance descriptivo-correlacional. En total se recuperaron 106 documentos sobre la enfermedad, publicados en revistas cubanas, con los cuales se conformó una base de datos "ad hoc" en el gestor bibliográfico EndNote X. Se identificó un total de 184 palabras clave. La aplicación de las medidas de centralidad reveló 43 nodos y 286 relaciones. Se aplicaron medidas de centralidad grado nodal e intermediación. En la red de co-palabras resultante se distinguieron 41 ítems y, agrupados por frecuencia de aparición conjunta, nueve clústeres de palabras clave. Las palabras clave más productivas se corresponden con la temática analizada; destacan los términos COVID-19, coronavirus, infección por coronavirus, SARS-CoV-2 y pandemia. El perfil temático de la producción científica sobre la COVID-19, publicada en las revistas médicas cubanas, demuestra la interdisciplinariedad de las investigaciones y se evidencia en el éxito de Cuba en el enfrentamiento a la pandemia.

The evaluation of scientific production has been of vital importance for the adequate development of scientific policies. In the current scenario, mediated by the pandemic and infoxication, the use of bibliometric methods is transcendental to know the development of scientific publications about COVID-19. The objective was to analyze the thematic profile of the scientific production on COVID-19, published in Cuban medical journals during the first 90 days of the pandemic. A bibliometric study was carried out, with a non-experimental design and a quantitative approach of descriptive-correlational scope. A total of 106 documents on the disease, published in Cuban journals, were recovered, with which an ad hoc database was created in the EndNote X bibliographic manager. A total of 184 keywords were identified. The application of centrality measures revealed 43 nodes and 286 relationships. Nodal degree centrality and intermediating measures were applied. In the resulting co-word network, 41 items and, grouped by frequency of joint occurrence, nine keyword clusters were distinguished. The most productive keywords correspond to the thematic analyzed; the terms COVID-19, coronavirus, coronavirus infection, SARS-CoV-2 and pandemic stand out. The thematic profile of the scientific production on COVID-19, published in Cuban medical journals, demonstrates the interdisciplinary nature of the research and is evidenced by Cuba's success in facing the pandemic.

Análisis de las interacciones entre los actores de la Red de Gestión del Conocimiento, Investigación e Innovación en Malaria de Colombia / Analysis of interactions between actors of the Red de Gestión del Conocimiento e Innovación en Malaria de Colombia

Introducción. La malaria, o paludismo, es una enfermedad de gran impacto en la población colombiana, que debe ser abordada desde el punto de vista del trabajo en equipo de instituciones para el intercambio de conocimiento. Objetivo. Analizar las interacciones de la Red de Gestión del Conocimiento, Investigación e Innovación en Malaria de Colombia. Materiales y métodos. Se hizo un análisis de redes sociales que permitió identificar la proximidad entre los actores y el grado de conocimiento entre ellos; se observaron indicadores de densidad, diámetro, distancia media y centralidad de grado. El corpus documental para el estudio estuvo constituido por 193 documentos técnicos publicados entre el 2016 y el 2021, que fueron analizados empleando técnicas de procesamiento de texto mediante el lenguaje de programación R. La categorización de la red se realizó a partir de cinco variables: atención integral a pacientes, diagnóstico, epidemiología y sistemas de análisis de información en salud, política pública, y promoción y prevención. Resultados. El análisis de las interacciones indicó que la red la conformaban 99 actores, de los cuales 97 (98 %), mostraron más interés en la producción de conocimientos en epidemiología y sistemas de análisis de información en salud, seguido de la categoría de atención integral a pacientes con 79 (80 %). El 54 % de los actores llevó a cabo estudios de promoción y prevención, siendo esta la categoría de menor abordaje. Conclusiones. Este estudio contribuye al fortalecimiento de estrategias clave en la divulgación del conocimiento sobre la malaria en Colombia.

Introduction: Malaria is a disease with a high impact on Colombian population, which must be approached from the point of view of teamwork of institutions for knowledge exchange. Objective: To analyze the interactions of the Red de Gestión del Conocimiento, Investigación e Innovación en Malaria de Colombia. Materials and methods: An analysis of social networks was applied that allowed identifying the proximity between actors and the degree of knowledge between them. Indicators of density, diameter, average distance, and degree of centrality were observed. The documentary corpus for the study consisted of 193 technical documents published between 2016 and 2021, which were analyzed using text mining using the R programming language. The network was categorized based on five variables: comprehensive patient care, diagnosis, epidemiology and health information analysis systems, public policy and promotion and prevention. Results: The analysis of interactions indicated that the network was made up by 99 actors. The main interest in knowledge production was on epidemiology and health information analysis systems (98 % of the actors), followed by the integral patient care (80 % of the actors). On the contrary, the least approached category was malaria promotion and prevention practices (54 % of the actors). Conclusions: In general, this study contributes to the strengthening of key strategies in the dissemination of knowledge about malaria in Colombia.

Lupus en Argentina. Pacientes no respondedores al tratamiento estándar y belimumab como posible opción. Datos del registro RELESSAR / Lupus in Argentina. Non-responders to standard treatment and belimumab as a possible option. RELESSAR record data

Introducción: el lupus es una enfermedad compleja y varias veces de difícil abordaje. Alcanzar la remisión es uno de los objetivos, incorporando opciones terapéuticas. Objetivos: describir las características generales de los pacientes según el estado de la enfermedad y el uso de belimumab. Materiales y métodos: estudio de corte transversal, registro RELESSAR. Se definió el estado de la enfermedad como: remisión: SLEDAI=0 y sin corticoides; baja actividad de la enfermedad: SLEDAI >0 y ≤4 y sin corticoides; control no óptimo: SLEDAI >4 y cualquier dosis de corticoides. Resultados: se incluyeron 1.277 pacientes, 23,4% en remisión, 12,6% en baja actividad y 63,8% con control no óptimo. En este último grupo eran más jóvenes y con menor duración de la enfermedad; presentaban mayores índices de actividad y cronicidad, y mayor empleo de inmunosupresores. Solo el 22,3% de los pacientes con criterio potencial de uso de belimumab (lupus eritematoso sistémico activo a pesar del tratamiento estándar) lo recibía en ese momento. Las variables asociadas a hospitalizaciones fueron: terapia con corticoides, ciclofosfamida y mayor SLICC. Conclusiones: se refleja la complejidad del manejo de estos pacientes y se visualizan aspectos estructurales como la desigualdad. El uso del belimumab resultaría beneficioso en los pacientes seleccionados.

Introduction: lupus is a complex disease and often difficult to approach. Achieving remission is one of the objectives, incorporating therapeutic options. Objectives: to describe the characteristics of the patients and the use of belimumab, according to the status of the disease. Materials and methods: cross-sectional study. Patients of the RELESSAR registry. Stratification: Remission: SLEDAI=0 and without corticosteroids. Low disease activity SLEDAI> 0 and ≤4 and without corticosteroids and non-optimal control: SLEDAI> 4 and any dose of corticosteroids. Results: a total of 1,277 patients were included, 23.4% in remission, 12.6% in low disease activity and 63.8% in non-optimal control. The last group was younger and had a shorter duration of the disease. They had higher activity and chronicity indices and greater use of immunosuppressants. Only 22.3% of the patients with potential criteria for the use of belimumab (activity disease despite standard treatment) were receiving it. The variables associated with hospitalizations were: corticosteroids, cyclophosphamide and higher SLICC. Those associated with severe infection: mycophenolate mofetil, azathioprine, corticosteroids, and higher SLICC. Conclusions: the complexity of the management of these patients is reflected, visualizing structural aspects such as inequality. The use of belimumab could be beneficial in selected patients.

Code-Switching Between Arabic and English in Selected Discourses

Code-switching is a linguistic phenomenon that has been studied on both written and spoken discourses in the recent years. This study is an attempt to analyze code-switching in selected discourses. The data were collected from Arabic Interviews on YouTube. The first interview 'Studying in the best university ever' is a broadcast by Abdullah Al-Alawy. The second interview 'Karak session' is with the broadcaster Mohammed Al-Hinai. The methodology of this study was a mixed (quantitative as well as qualitative) method. The research tries to answer three questions: 1.How many code- switching Instincts from Arabic language to English language occurred in the selected discourses? 2. Is there any translation for the code-switching? If yes, then where the translation takes its place whether before or after the code- switching? 3. How many intra-word switching occur by using Arabic grammatical morphemes within these English code-switching? The research's primary goal is to improve our understanding of the instinctive uses of code-switching from Arabic to English. In this study I found that there are 101 occurrences of code-switching within about forty minutes of Arabic discourses. The most frequent type of code-switching in these two discourses was intra-sentential code-witching. While the least used one was inter-sentential code-switching. Most of the code-switching Instincts occurred without any translation to Arabic

Combining statistics: the role of phonotactics on cross-situational word learning

Abstract Language learners can rely on phonological and semantic information to learn novel words. Using a cross-situational word learning paradigm, we explored the role of phonotactic probabilities on word learning in ambiguous contexts. Brazilian-Portuguese speaking adults (N = 30) were exposed to two sets of word-object pairs. Words from one set of labels had slightly higher phonotactic probabilities than words from the other set. By tracking co-occurrences of words and objects, participants were able to learn word-object mappings similarly across both sets. Our findings contrast with studies showing a facilitative effect of phonotactic probability on word learning in non-ambiguous contexts.

Reading digital- versus print-easy texts: a study with university students who prefer digital sources

The transition from on-paper to on-screen reading seems to make it necessary to raise some considerations, as a greater attentional efort has been claimed for print texts than digital ones. Not surprisingly, most university students prefer this digital medium. This research aims to examine reading times by contextualizing this phenomenon into two processes: namely, word recognition and reading comprehension task on paper and on screen. Thus, two diferent tasks­counterbalanced into digital and print mediums­were carried out per each participant with a preference for a digital medium: a reading comprehension task (RCT) and a lexical decision task (LDT) after reading a specifc story. Participants were slower reading print texts and no statistically signifcant diferences were found in RCT accuracy. This result suggests that the task required more cognitive resources under the print medium for those with a worse comprehension performance in reading, and a more conservative pattern in digital RCT for those with a better performance.

Among Body, Image, and Word: the Power of The Libido / Entre Corpo, Imagem e Palavra: O Poder da Libido

Abstract This article originated from the will to understand how Freud formulates, in his theoretical work, the importance of the word, despite how obvious it may seem to use it as a tool for psychic treatment. Therefore, we researched the basis of his thoughts to check how he elaborates it so that we could address the question appropriately. Not only did we notice that Freud thinks of the word as one of the dimensions in which the libidinal energy goes through the psychophysiological mechanism, but also, it came to our attention that we should consider the interconnection between the body and the images of the soul [seele] to understand the function of the word in his work.

Resumo Deixando de lado a aparente obviedade de utilizar a palavra como ferramenta para o tratamento psíquico, o presente artigo partiu do desejo de compreender como Freud formulou a importância da palavra em sua obra teórica. Para que a matéria fosse devidamente tratada, buscamos nas bases do pensamento freudiano sua elaboração. Esta pesquisa permitiu-nos entender que Freud formula a palavra como uma das dimensões em que a energia libidinal transita no aparelho psicofisiológico. Não só isso, proporcionou-nos a ponderação de que é preciso reconhecer a interdependência entre o corpo e alma [Seele] para que a função da palavra seja devidamente compreendida em sua obra.

Factors Related to Real-world Suspected Allergic Reaction of Elememe Emulsion Injection / 中国实验方剂学杂志

ObjectiveTo analyze factors related to the suspected allergic reaction of elememe emulsion injection based on hospital information system. MethodData on cases that used elememe emulsion injection were collected from the information systems of 60 first-class hospitals nationwide. The nested case-control design method was adopted. Finally， 30 cases were included in the suspected allergy group and 120 cases in the control group. SAS 9.3 was employed for descriptive analysis of the gender， age， occupation， admission route， conditions of patients at the admission， and the diagnosis with frequency and percentage. The factors affecting the occurrence of suspected allergic reaction were analyzed by conventional logistic regression and propensity score weighted logistic regression. In the case that the number of independent variables was larger than the sample number， MCP （minimax concave penalty） was used to screen the key variables and the conditions of patients at admission， conditions of patients during hospitalization， hospital stay， diagnostic information， and medication information were compared between two groups. ResultThe male-to-female ratio was about 2∶1 in both groups and most of the patients were 46-65 years old. Patients in the control group were mainly "professional and technical personnel"， and the majority in the suspected allergy group were "business and service personnel" and "clerks and related personnel". They were mainly admitted at the outpatient and conditions of patients were average at the admission. Compared with the control group， suspected allergy group showed severe conditions during the hospitalization， short average hospital stay， large proportion with intravenous infusion， and low cure rate and effective rate. The results of logistic regression analysis showed no statistical difference in conditions of patients at admission， hospital stay， combined diseases， medicine dosage， and treatment course. ConclusionThe suspected allergic reaction of elememe emulsion injection mainly occurs in the first administration with rapid onset even with the dose lower than the commonly used one. The occurrence is related to the intravenous infusion and the severe conditions of patients during hospitalization and has nothing to do with the conditions of patients at admission， hospital stay， treatment course， use of other medicines， and diagnostic information. In summary， it is mainly related to the constitution and immune status of patients.

Differences in emotional conflict and cognitive fusion among patients with major depressive disorder with high and low suicidal ideation / 中华行为医学与脑科学杂志

Objective:To compare the differences of emotional conflict and cognitive fusion between depression patients with high and low suicidal ideation.Methods:Beck scale for suicide ideation-Chinese version(BSI-CV), Hamilton depression scale-17(HAMD-17), Beck depression inventory (BDI) and cognitive fusion questionnaire (CFQ) were used for evaluation.The 2×2×2 word-face Stroop task hybrid experimental design was used to compare the response time and accuracy of emotional face judgment in patients with depression with high suicidal ideation( n=22) and patients with depression with low suicidal ideation( n=22) using two-factor repeated measure ANOVA.BSI-CV scores of the two groups( n=44) were used as the dependent variable, and the reaction time of happy face, angry face, consistent face, inconsistent face, BDI score and CFQ score were used as independent variables to perform multiple linear stepwise regression analysis. Results:Both high and low suicidal ideation depression patients had emotional conflict effect in the word-face Stroop task, that was, compared with the face word inconsistent condition, the participants in the face word consistent condition had shorter response time ((707.19±128.79)ms vs (793.55±148.33)ms, F(1, 41)=11.38, P<0.01, ηp2 =0.217)and higher accuracy(95.85±4.50)%, (84.77±11.54)%, ( F(1, 41) =6.06, P<0.05, ηp2 =0.129). Under the condition of consistent face words, the response time of depression patients with high suicidal ideation was longer than that of depression patients with low suicidal ideation((803.69±91.35) ms, (610.69±78.13)ms, P<0.01). The main effect of facial expression type was not statistically significant between the two groups, that was, depression patients with high and low suicidal ideation did not show attentional bias to happy faces or angry faces( F(1, 41) =0.68, P=0.413, ηp2 =0.016). Regression analysis results showed depression score, cognitive fusion score, and reaction time of inconsistent face had positively predictive effects on BSI-CV score( β=0.40, 0.29, 0.29, all P<0.05). Conclusion:The cognitive fusion degree of the depression patients with high suicidal ideation is different from that of the depression patients with low suicidal ideation, but there is no difference in the emotion recognition. Reaction time of inconsistent face, cognitive fusion score and depression score have positively predictive effects on suicidal ideation.

Current trends in research on pulmonary fibrosis and metabolites: A bibliometric analysis / 环境与职业医学

Background Certain metabolites are closely related to the occurrence and development of pulmonary fibrosis, and the related mechanism has not been fully elucidated. It is necessary to explore the trends of various metabolites and causes of pulmonary fibrosis. Objective To discuss the trends of publication and research hotspots of pulmonary fibrosis-related metabolites by bibliometrics. Methods With "pulmonary fibrosis" and "metabolites" in both Chinese and English as primary keywords, literature search was conducted through public online databases: PubMed, Web of Science, SinoMed, and CNKI. NoteExpress 3.0 and Excel 2019 were used to store and organize the collected literature. Analyses included publication year, number of papers, institution, country/region, and journal title. VOSviewer 1.6.10 was used for visual analysis. Keyword co-occurrence was analyzed by setting the minimum threshold for the occurrence of keywords to 5 times. Results The research on pulmonary fibrosis and associated metabolites in foreign language was earlier than that in Chinese language. Since the 1990s, the number of literature showed an increasing trend in both foreign and Chinese language literature. A total of 1 062 articles were published in foreign languages, of which 864 articles contained the authors’ address information. The authors in the United States published 340 articles, followed by China with 196 articles, and then Japan, Germany, and Italy. There were 728 relevant pieces of literature published in Chinese, 709 of which included the authors’ institution information and 350 institutions were involved. North China University of Science and Technology, Shanxi Medical University, Peking University, Zhengzhou University, China Medical University，and Soochow University were the top 6 by number of publication. A total of 255 Chinese journals published 728 Chinese articles, and among them 242 articles (33.24%) were published by 12 journals having published more than ten articles per journal. A total of 1062 articles were published in 609 foreign language journals, and among them 179 articles (16.85%) were published by 8 journals with more than 15 articles published by each journal. The results of keywords co-occurrence analysis suggested that pulmonary fibrosis in association with glucose metabolism, lipid metabolism, amino acid metabolism, nucleotide metabolism, and biological oxidation were the common themes studied at home and abroad. Conclusion The number of publications on pulmonary fibrosis and metabolites has been on the rise in recent years, and the research hotspots include glucose metabolism, lipid metabolism, amino acid metabolism, nucleotide metabolism, and biological oxidation.

A co-word cluster analysis on hot-spots of foreign nursing research on liver transplantation / 中国实用护理杂志

Objective:To analyze the research hotspots of foreign liver transplantation nursing, and explore the current research trends in this field.Methods:The subject words of liver transplantation nursing literature included in Web of Science were used as the research object, the retrieval time was from the establishment of the database to November 24, 2021, and Bicomb software was used for word frequency analysis, and SPSS software was used carry out systematic clustering analysis on high-frequency keywords.Results:Two hundred and ninety-four articles were finally included and published in 169 journals. Thirty high-frequency subject words were extracted, accounting for 47.60% of the total frequency. Through co-word cluster analysis, it is found that research hotspots include 7 categories: pediatric liver transplantation and family, quality of life and transitional care, postoperative complications and psychology, organ donation and ethics, treatment compliance, intensive care and psychiatry, nutrition and symptoms management.Conclusions:It is suggested that the future nursing research of liver transplantation in China should focus on pediatric living donor liver transplantation and family management, symptom management of liver transplantation recipients, nutrition management of pediatric liver transplantation recipients, psychiatric complications after transplantation in ICU, nursing ethics of liver transplantation, etc. So as to improve the nursing development level of liver transplantation in China.

Research progress in the application of functional near infrared spectroscopy in children language development / 中华实用儿科临床杂志

Functional near infrared spectroscopy (fNIRS) is an emerging neuroimaging technology, which has such advantages as non-invasiveness, portability, robustness to motion and no noise over other neuroimaging tools.Therefore, it has important values in the research of children language development.fNIRS has been currently applied to the study of neonatal word recognition, infant speech perception, language functional lateralization, bilingual cognitive mechanism, language related neurodevelopmental disorders, etc.It has a bright future of applications in the field of children language development.

Dupla Rota na Leitura e Compreensão Leitora no Português do Brasil / Dual Route in Reading and Reading Comprehension in Brazilian Portuguese / Ruta Dual en Lectura y Comprensión Lectora en Portugués Brasileño

O Modelo de Leitura de Dupla Rota é relevante tanto para o entendimento do processo de leitura como para a compreensão leitora. Este estudo objetivou investigar a contribuição da consciência fonológica (rota fonológica) e do reconhecimento de palavras (rota lexical), bem como do ano escolar para a habilidade de leitura em voz alta de palavras isoladas e a compreensão de leitura no português do Brasil. Participaram desta pesquisa 443 alunos do 3º ao 5º ano de Ensino Fundamental I, de escolas públicas de todas as regiões do Brasil. Os instrumentos utilizados foram o Cloze 1 e Cloze 2, Prova de Leitura do Teste de Desempenho Escolar, Roteiro de Avaliação de Consciência Fonológica e Escala de Reconhecimento de Palavras. Os resultados indicaram que o valor explicativo da mediação do reconhecimento de palavras na relação preditiva indireta da consciência fonológica foi maior para compreensão de leitura do que para leitura. A contribuição explicativa da mediação do reconhecimento de palavras na relação preditiva do ano escolar apresentou valores próximos para leitura e compreensão de leitura. É possível concluir que mesmo com o controle do ano escolar, tanto a rota fonológica como a rota lexical predizem a leitura e a compreensão leitora. (AU)

The Dual Route Reading Model is relevant to both understanding the reading process and reading comprehension. This study aimed to investigate the contribution of phonological awareness (phonological route) and word recognition (lexical route) and the school year for the ability to read aloud single words and reading comprehension in Brazilian Portuguese. Participated 443 students from Elementary School (3rd to the 5th grade). The schools were public and are located in the five regions of Brazil. The instruments used were Cloze 1 and Cloze 2, School Performance Test Reading Test, Phonological Awareness Assessment Guide, and Word Recognition Scale. The results indicated that the explanatory value of mediating word recognition in the indirect predictive relationship of phonological awareness was greater for reading comprehension than for reading. The explanatory contribution of the mediation of word recognition in the predictive relationship of the school year presented similar values for reading and reading comprehension. It is possible to conclude that even with the control of the school year, both the phonological route and the lexical route predict reading and reading comprehension. (AU)

El modelo de lectura de ruta dual es relevante tanto para comprender el proceso de lectura como para la comprensión lectora. Este estudio tuvo como objetivo investigar la contribución de la conciencia fonológica (ruta fonológica) y el reconocimiento de palabras (ruta léxica), así como el año escolar para la capacidad de leer en voz alta palabras sueltas y la comprensión lectora en portugués brasileño. En esta investigación participaron un total de 443 estudiantes del 3º al 5º grado del Ensino Fundamenral, de escuelas públicas de todas las regiones de Brasil. Los instrumentos utilizados fueron Cloze 1 y Cloze 2, Prueba de Desempeño Escolar, Prueba de Lectura, Guía de Evaluación de la Conciencia Fonológica y Escala de Reconocimiento de Palabras. Los resultados indicaron que el valor explicativo de mediar en el reconocimiento de palabras en la relación predictiva indirecta de la conciencia fonológica fue mayor para la comprensión lectora que para la lectura. El aporte explicativo de la mediación del reconocimiento de palabras en la relación predictiva del curso escolar presentó valores similares para lectura y comprensión lectora. Es posible concluir que aún con el control del curso escolar, tanto la vía fonológica como la vía léxica predicen lectura y comprensión lectora. (AU)

Caracterización de un corpus extraído de historias clínicas electrónicas de maternas a través de técnicas de procesamiento de lenguaje natural / Characterization of a corpus extracted from maternal electronic health records through natural language processing techniques

Este artículo tuvo como propósito caracterizar el texto libre disponible en una historia clínica electrónica de una institución orientada a la atención de pacientes en embarazo. La historia clínica electrónica, más que ser un repositorio de datos, se ha convertido en un sistema de soporte a la toma de decisiones clínicas. Sin embargo, debido al alto volumen de información y a que parte de la información clave de las historias clínicas electrónicas está en forma de texto libre, utilizar todo el potencial que ofrece la información de la historia clínica electrónica para mejorar la toma de decisiones clínicas requiere el apoyo de métodos de minería de texto y procesamiento de lenguaje natural. Particularmente, en el área de Ginecología y Obstetricia, la implementación de métodos del procesamiento de lenguaje natural podría ayudar a agilizar la identificación de factores asociados al riesgo materno. A pesar de esto, en la literatura no se registran trabajos que integren técnicas de procesamiento de lenguaje natural en las historias clínicas electrónicas asociadas al seguimiento materno en idioma español. En este trabajo se obtuvieron 659 789 tokens mediante los métodos de minería de texto, un diccionario con palabras únicas dado por 7 334 tokens y se estudiaron los n-grams más frecuentes. Se generó una caracterización con una arquitectura de red neuronal CBOW (continuos bag of words) para la incrustación de palabras. Utilizando algoritmos de clustering se obtuvo evidencia que indica que palabras cercanas en el espacio de incrustación de 300 dimensiones pueden llegar a representar asociaciones referentes a tipos de pacientes, o agrupar palabras similares, incluyendo palabras escritas con errores ortográficos. El corpus generado y los resultados encontrados sientan las bases para trabajos futuros en la detección de entidades (síntomas, signos, diagnósticos, tratamientos), la corrección de errores ortográficos y las relaciones semánticas entre palabras para generar resúmenes de historias clínicas o asistir el seguimiento de las maternas mediante la revisión automatizada de la historia clínica electrónica(AU)

The purpose of this article was to characterize the free text available in an electronic health record of an institution, directed at the care of patients in pregnancy. More than being a data repository, the electronic health record (HCE) has become a clinical decision support system (CDSS). However, due to the high volume of information, as some of the key information in EHR is in free text form, using the full potential that EHR information offers to improve clinical decision-making requires the support of methods of text mining and natural language processing (PLN). Particularly in the area of gynecology and obstetrics, the implementation of PLN methods could help speed up the identification of factors associated with maternal risk. Despite this, in the literature there are no papers that integrate PLN techniques in EHR associated with maternal follow-up in Spanish. Taking into account this knowledge gap, in this work a corpus was generated and characterized from the EHRs of a gynecology and obstetrics service characterized by treating high-risk maternal patients. PLN and text mining methods were implemented on the data, obtaining 659 789 tokens and a dictionary with unique words given by 7 334 tokens. The characterization of the data was developed from the identification of the most frequent words and n-grams and a vector representation of embedding words in a 300-dimensional space was performed using a CBOW (Continuous Bag of Words) neural network architecture. The embedding of words allowed to verify by means of Clustering algorithms, that the words associated to the same group can come to represent associations referring to types of patients, or group similar words, including words written with spelling errors. The corpus generated and the results found lay the foundations for future work in the detection of entities (symptoms, signs, diagnoses, treatments), correction of spelling errors and semantic relationships between words to generate summaries of medical records or assist the follow-up of mothers through the automated review of the electronic health record(AU)