Histomorphological, Histochemical and Ultrastructural Studies on the Healthy Liver of Yemen Veiled Chameleon (Chamaeleo calyptratus) in Southern Saudi Arabia / Estudios Histomorfológicos, Histoquímicos y Ultraestructurales en el Hígado Sano del Camaleón Velado de Yemen (Chamaeleo calyptratus) en el Sur de Arabia Saudita

SUMMARY: The livers of reptiles are being studied as a model for the link between the environment and hepatic tissue. There have been few investigations on the histology of reptile livers, and very few or no studies have examined the histology of liver of veiled chameleon (Chamaeleo calyptratus). This paper describes the histomorphological, histochemical and ultrastructural characterization of the liver of veiled chameleons in southern Saudi Arabia. Seven Chamaeleo calyptratus were captured in the summer season in Abha City, Aseer region, southern Saudi Arabia. Chamaeleon liver samples were processed for histomorphology, histochemistry and ultrastructure analyses. Morphologically liver of Chamaeleo calyptratus was observed as a large dark brown organ with lighter speckles, which represent melanin deposits. It located at the ventral part of abdominal cavity forward of the stomach. Its dimensions approximately were 3.7 x 2 cm. The liver was a bilobed organ divided into two lobes, right and left lobes. The right one was bigger than the others. The gallbladder was well developed and had an elongated shape, situated between the two lobes and contained the bile for the digestion. Microscopically, the liver was found to be covered by a thick layer of connective tissue, which formed the hepatic capsule. Hepatic parenchyma probably appeared in cross sections as hepatic glandular-like alveoli "acini" or follicular structures with various diameters, each acinus contains approximately four to six hepatocytes, surrounded by sinusoidal capillaries filled with abundant melanomacrophages, which are absent in birds and mammals. Melanomacrophages are common in the hepatic parenchyma's perisinusoidal areas, particularly near portal spaces. Hepatocytes are polyhedral or pyramidal with and mostly contained large, rounded nuclei mostly peripherally located, with prominent dark oval nucleoli. Some of nuclei are eccentric or central position. The cytoplasm appeared spongy or vacuolated and more eosinophilic when stained by hematoxylin-eosin and strongly reactive to PAS staining technique, indicating abundant glycogen content. The reticular fibers that surround hepatocytes, blood arteries, and sinusoids supported the hepatic parenchyma. The blood sinusoids are seen interspersed among hepatocytes of varying sizes. The sinusoidal lumen was bordered by flattened endothelial cells and includes elliptical nucleated erythrocytes and liver macrophages as phagocytes, which are also known as Kupffer cells. Branches of the portal vein, hepatic artery, small bile duct, and lymph vessels were detected in the hepatic portal area "tract" or triad which made up of connective. Hematopoietic tissue was observed in subcapsular region and portal triads. Ultrastructurally, the hepatocyte appeared polyhedric containing a single large rounded basal or eccentric vesicular nucleus with prominent nucleolus. Extensive network of rough endoplasmic reticulum (RER) often arranged in an array parallel to the nuclear membrane with many mitochondria, and Golgi apparatus were described. The cytoplasm contained glycogen granules, vesicles or vacuoles scattered throughout the cytoplasm especially at the apical region were reported. The bile canaliculi and the hepatic "Kupffer" cells were also discussed. This is the first study on the histological characterization of the healthy liver of Yemen veiled chameleon in southern Saudi Arabia. The findings reported here should be used as a reference to compare with the pathological abnormalities of the liver in this animal.

está disponible en el texto completo

Effect of Smoking on Serum Lipid Profile among University’s Students in Dhamar City, Yemen

A cross sectional study was performed to evaluate the changes on serum lipid profile and associated risk factors in apparently healthy smoker and non-smoker students at the University of AlHikma Dhamar city, Yemen during the period between November 2021 to March, 2022. Two hundred five students were randomly selected, 104 students were smokers and 101 nonsmokers. Sociodemographic data were collected using a self-administered questionnaire. Anthropometric measurements and laboratory analysis for lipid profile were assessed using standard techniques. The results revealed that smokers had significantly (P<0.05) higher levels of TC (164.93 mg/dl), TG (149.63 mg/dl), LDL (71.60 mg/dl) and VLDL (29.58 mg/dl) and lower level of HDL (64.70 mg/dl) compared to the non-smokers group. Duration and numbers of cigarette smoked were positively correlated with lipid profile values of participants (r=.300; P=.000 and r= .317; P.=000) and (r=.210; P=.003 and r=.213; P=.002) for TG and VLDL respectively; while none with other values. Significant association was observed between weight (r=.235; P=.001 and r=.145; P=.000); heartbeat (r=.205; P=.003 and r=.256; P=.000); diastolic (r=.151; P=.030) and BMI (r=.155; P=.027) indices and lipid profile (TG and VLDL); (TC and LDL); (HDL and TC) of the participants respectively; whereas, none with height and systolic indices. In conclusion, smoking is clearly associated with increase serum lipid and lipoprotein values with exception HDL which significantly decreased in smoker compared to non-smokers students. This association is dependent on number of sociodemographic and anthropometric factors. Adopting anti-smoking programs among University`s students to prevent the harmful effects of smoking are urgently required.

Mycetoma in north-western Yemen: Clinico-epidemiological and histopathological study

Background: Mycetoma is widespread in Yemen; however, there are only a few documented reports on the entity from this geographical area. Methods: A prospective study of 184 cases of mycetoma (male 145 and female 39) from different regions of north-western Yemen was conducted between July 2000 and May 2014. Clinical profile was recorded in a standardized protocol. The diagnosis was based on clinical features, X-ray studies, examination of grains, and histopathology. Results: Eumycetoma was diagnosed in 129, caused by Madurella mycetomatis in 124, Leptosphaeria senegalensis in one and pale grain fungus in four, whereas actinomycetoma occurred in 55, caused by Streptomyces somaliensis in 29, Actinomadura madurai in nine, Actinomadura pelletieri in one, and Nocardia in sixteen. Eumycetoma cases were treated with prolonged course of antifungal drugs, mostly ketoconazole, with itraconazole being used in four patients, along with excision or debulking. Results were better when antifungal drugs were given two to three months before surgery and in those who received itraconazole. Actinomycetoma cases were initially treated with co-trimoxazole monotherapy; later streptomycin was added in 30 cases. Six patients who did not show adequate improvement and two others from the start were treated with modified Welsh regimen and with good results. Limitations: Identification of different causative agents was done by histopathology and could not be reconfirmed by culture. Conclusion: Mycetoma is widespread in north-western Yemen with a higher incidence of eumycetoma and a majority of the cases were caused by Madurella mycetomatis. Modified Welsh regimen in actinomycetoma and itraconazole with excision in eumycetoma showed the best results.

Epidemiological Characteristic of Malaria Coinfected with Dengue Fever in Hodeidah, Yemen

Introduction:Malaria and dengue fever are the most prevalent vector-borne diseases in tropical areas and represent major public health problems.They are transmitted by mosquito namely Anophelesand Aedes aegypti, respectively. Hodeidah is a high density with these vectors. Also, co-infection of these diseases has (malaria and dengue) become undetected due to lack of suspicious clinical suspicion and overlapping symptoms.Aim of the Study:The study aimed to detect the prevalence of co-infection with malaria and dengue fever, determine the clinical presentation within febrile patients in Hodeidah city and determine some potential risk factors associated with co-infection.Methods: A cross-sectional study was conducted (from January to December 2017) in febrile patients. All patients were designedinto three groups: Group A (co-infected with malaria and dengue); Group B (malaria as mono-infection) andGroup C (dengueasmono-infection). The diagnosis of malaria was by microscopic and rapid diagnostic test (RDT) and the dengue virus was detected using enzyme-linked immunosorbent assay (ELISA). The diagnosis was performed in Center of Tropical Medicine and Infectious Diseases (CTMID),Authority of AL-Thawra Public Hospital-Hodeidah, in collaboration with the Tihama Foundation for Medical-Pharmaceutical Studies and Research (TFMPSR), Hodeidah, Yemen. Results: Out of 270 febrile patients, 82cases(30.4%) patients weremalaria –dengue coinfection, 100 cases (37.0%) of malaria, 21 cases (7.7%) ofdengue and 67 cases (24.8%) werenon-malaria and non-dengue. The most common symptoms were fever, headache, arthralgia, myalgia and retro-orbital pain, where the clinical symptoms of co-infected patients were more like dengue than malaria. One death was reported in malaria –dengue coinfection, with a case fatality rate (CFR%) of 1.2% (1/82).Conclusion:Our results show a high prevalence of malaria –dengue coinfecionin Hodeidah, Yemen as the first time. These due to a high density of vectors in this region and endemic areas for malaria and dengue. Furthermore, surveillance strategies, preventive measures and healthcare worker's education are critical for curtailing this problem and lifesaving.

Association of Khat chewing, smoking, age and sex with periodontal status among Yemeni adults / Associação da mastigação de Khat, tabagismo, idade e gênero com a condição periodontal entre adultos iemenitas

Objective: Periodontal diseases are very common dental disease. Many risk factors may play significant role in the periodontal disease initiation and progression. This study was performed to evaluate the effects of khat chewing, smoking, age and gender on periodontal status among Yemeni adults. Material and Methods: This cross-sectional study was performed on 1231 patients attending the outpatient dental polyclinics of University of Science and Technology during the academic years 2017/2018. All completed sheets were collected throughout the year by the supervisors. Data cleaning, descriptive statistics, and inferential statistics were then performed. Results: Khat chewers were more frequent than non-chewers counterparts (60.7% vs. 39.3%). The prevalence of smoking was 25.5% (297 patients). Study results indicated that periodontitis is more associated with female gender and participants aged more than 35 years old. Results also showed that female and age older participants aged more than 35 years were significantly associated with gingival recession. Mean number of the teeth with gingival recession in male patients were higher than in females. Male gender and patients aged more than 35 years old were significantly associated with furcation involvement. Conclusion: The present study has shown females gender and age older than 35 seem to be risk factors of periodontal diseases. Males has more teeth affected by gingival recession and more furcation involvement (AU)

Objetivo: As doenças periodontais são patologias dentárias com alta prevalência. Diversos fatores de risco podem desempenhar papel significativo no início e progressão das doenças periodontais. Este estudo foi realizado para avaliar os efeitos da mastigação de khat, tabagismo, idade e gênero na condição periodontal de adultos iemenitas. Material e Métodos: Este estudo transversal foi realizado em 1231 pacientes atendidos nas policlínicas odontológicas ambulatoriais da Universidade de Ciência e Tecnologia durante os anos acadêmicos de 2017/2018 através de um questionário para coleta de dados préestabelecido. Todas os questionários preenchidos foram coletados ao longo do ano pelos supervisores. A apuração dos dados, estatística descritiva e estatística inferencial foram realizadas. Resultados: os mastigadores de Khat foram mais frequentes do que as não-mastigadores (60,7% vs. 39,3%). A prevalência de tabagismo foi de 25,5% (297 pacientes). Os resultados do estudo indicaram que a periodontite está mais associada ao gênero feminino e aos participantes com mais de 35 anos de idade. Os resultados também mostraram que participantes do gênero feminino e acima de 35 anos foram significativamente associadas à recessão gengival. O número médio de dentes com recessão gengival em pacientes do gênero masculino foi maior que no feminino. O gênero masculino e os pacientes com mais de 35 anos de idade foram significativamente associados ao envolvimento da furca. Conclusão: O presente estudo mostrou que o gênero feminino e a idade acima de 35 anos parecem ser fatores de risco para doenças periodontais. Pacientes do gênero masculino têm mais dentes afetados pela recessão gengival e mais envolvimento de furca.(AU)

Transverse Cerebellar Diameter as a Sonographic Parameter for Estimating Gestational Age: an Experience From Yemeni Population

@#Introduction: Estimation of gestational age (GA) is clinically crucial for managing pregnancy and assessing the foetal anatomy, growth and development. Transverse cerebellar diameter (TCD) has been reported as an accurate tool for dating the pregnancy. This study aimed to determine the accuracy of foetal TCD for dating the pregnancy and to construct a reference chart for GA of Yemeni foetuses. Methods: We conducted this prospective cross-sectional study among 400 Yemeni pregnant women between 18 and 40 weeks of gestation provided that they were with known last menstrual period and singleton normal pregnancies. Sonographic TCDs were measured for each foetus. The mean TCD was measured for gestational weeks separately, and a polynomial regression model was then used to predict the GA by TCD. Results: There was a robust correlation between GA and TCD (r = 0.995, p <0.001). The coefficient of determination was 0.989, which indicates that the TCD explains 98.9% of GA change. Conclusion: TCD is an accurate tool to estimate the GA in second and third trimesters, including final weeks, among Yemeni pregnant women as in developed countries. The narrow range between the 5% and 95% percentiles is a significant indication of the accuracy of the TCD in estimating the GA. Therefore, clinicians are recommended to use TCD for estimating the GA and should be trained on measuring it accurately.

Knowledge and Practice of Breastfeeding among Mothers in Arma’a District Shabwah Governorate - Yemen

@#Breastfeeding is almost universal, but there are many barriers for proper breast feeding practices. Inadequate knowledge, or inappropriate practice, of breastfeeding may lead to undesirable consequences. The aim of this study was to assess breastfeeding knowledge, and practice among mothers in Arma’a district Shabwah governorate and identify factors that may affect breastfeeding practice in the study population. A cross-sectional study using pre-tested validated structured questionnaire conducted among mothers who were attending Arma’a hospital and four health care units around Arma'a district. Sample size was 130 mothers who had at least one child aged two years or younger. Breastfeeding knowledge and practice of participants were assessed based on their experience with the last child.This study found that there are only 24 mothers (18.6%) have good knowledge while 106 mothers (81.4%) have low knowledge. 63 mothers (48.5%) had good breastfeeding practice while 67 mothers (51.5%) have poor breastfeeding practice. 54.0% mothers that have good knowledge have good practice while 52.8% mothers of poor knowledge have poor practice. Mothers’s knowledge was significantly associated with their education level and their practice was significantly associated with the number of pregnancies (p-value=0.04 and =0.027 respectively). There was no significant association with other demographic data, and between knowledge and practice. No exclusive breastfeeding reported in this study.This study shows that undesirable cultural practices such as giving pre-lacteal, avoiding exclusive breastfeeding are still prevalent among the mothers. The maternal knowledge towards breastfeeding was very low and there was big gap between actual and desired practices.

The Reliability of Fishman and Nolla Methods in Prediction of Chronological Age of Yemeni Children / A confiabilidade dos métodos Fishman e Nolla na predição da idade cronológica de crianças iemenitas

Objective: This cross-sectional school based study aimed to assess the reliability of Fishman and Nolla methods in predicting the chronological age for Yemeni children. Material and Methods: Orthopantomographs and left handwrist radiographs were taken for 358 Yemeni children (193 boys and 165 girls) 8 - 16 years. Skeletal age estimated by Fishman method and dental age estimated by Nolla method were compared to chronological age using SPSS version 21, statistical significance was predetermined at P < 0.05 , using Intraclass Correlation CoefficientICC and Wilcoxon signed rank test. Results: The mean chronological, skeletal and dental ages were 12.00 ± 2.25 years, 12.39 ± 1.65 years and 11.32 ± 2.65 years, respectively. Intraclass correlation coefficient showed strong correlation between chronological age and skeletal and dental ages. Wilcoxon test showed Fishman method significantly underestimated the chronological age by 0.44 ± 1.26 years in boys and non-significantly underestimated the chronological age by 0.02 ± 1.08 years in girls. Nolla method significantly underestimated the chronological age by 0.59 ± 1.28 years in boys and 0.78 ± 1.21 years in girls. Conclusions: Chronological age of Yemeni children is highly correlated to skeletal age estimated by Fishman method and dental age estimated by Nolla method. However, the two methods underestimate the chronological age of Yemeni children.(AU)

Objetivo: Este estudo transversal de base escolar teve como objetivo avaliar a confiabilidade dos métodos Fishman e Nolla na predição da idade cronológica em crianças iemenitas. Material e Métodos: Foram realizadas ortopantomografias e radiografias do punho esquerdo em 358 crianças iemenitas (193 meninos e 165 meninas) de 8 a 16 anos. A idade esquelética estimada pelo método Fishman e a idade odontológica estimada pelo método Nolla foram comparadas com a idade cronológica pelo, utilizando-se o programa SPSS versão 21; a significância estatística foi predeterminada em P < 0,05, pelo coeficiente de correlação intraclasseICC e pelo teste de Wilcoxon. Resultados: As idades cronológica, esquelética e odontológica média foram de 12,00 ± 2,25 anos, 12,39 ± 1,65 anos e 11,32 ± 2,65 anos, respectivamente. O coeficiente de correlação intraclasse mostrou forte correlação entre idade cronológica e idade esquelética e dentária. O teste de Wilcoxon mostrou que o método Fishman subestimou significativamente a idade cronológica em 0,44 ± 1,26 anos nos meninos e não subestimou significativamente a idade cronológica em 0,02 ± 1,08 anos nas meninas. O método Nolla subestimou significativamente a idade cronológica em 0,59 ± 1,28 anos nos meninos e 0,78 ± 1,21 anos nas meninas. Conclusões: A idade cronológica de crianças iemenitas está altamente correlacionada à idade esquelética estimada pelo método Fishman e à idade dentária estimada pelo método Nolla. No entanto, os dois métodos subestimam a idade cronológica das crianças iemenitas.(AU)

The prevalence of tooth wear among a group of yemeni adults / La prevalencia del desgaste dental entre un grupo de adultos yemeníes

This study aimed at investigating tooth wear prevalence and determining the associated factors among a group of Yemeni adults. It is a preliminary cross-sectional and analytical investigation conducted on 600 participants aged 20­50 years. The participants were purposively selected from two main cities (Sana'a and Aden) with an equal sample size and divided equally by gender. For administering a questionnaire, interviews were conducted with all participants before clinically examining them. Using the Tooth Wear Index (TWI), tooth wear was assessed. Data were analyzed using the chi-square test to identify the relationship between tooth wear and associated factors., Tooth wear was prevalent among 78.67% of the participants; of which 64.83% were in anterior teeth, 63.83% in posterior teeth, 74% in maxillary teeth, and approximately 74.5% in mandibular teeth. It also was 100% prevalent in the 31-40 and 41-50 age groups, while it was 67.2% in the 20-30 age group. This showed that tooth wear prevalence was significantly higher in the two oldest groups than in the youngest group (p<0.001). Moreover, khat chewing, location, highly frequent consumption of foods and high frequency of acidic drinks consumption were critical indicators of tooth wear. Besides, a low education level, smoking and a low socio-economic status were associated with tooth wear. Finally, the study revealed that tooth wear is highly prevalent among adults in two Yemeni cities, and socio-behavioral risk indicators such as khat chewing and cigarette smoking have a significantly association with tooth wear.

Este estudio tuvo como objetivo investigar la prevalencia del desgaste dental y determinar los factores asociados en un grupo de adultos yemeníes. Es una investigación preliminar analítica y transversal que se lleva a cabo en 600 participantes de entre 20 y 50 años. Los participantes fueron seleccionados a propósito de dos ciudades principales (Sana'a y Aden) con un tamaño de muestra igual y divididos por igual por género. Para administrar un cuestionario, se realizaron entrevistas con todos los participantes antes de examinarlos clínicamente. Usando el Índice de Desgaste Dental, se evaluó el desgaste dental. Los datos se analizaron utilizando la prueba de chi-cuadrado para identificar la relación entre el desgaste dental y los factores asociados. El degaste dental tuvo una prevalencia del 78,67% de los participantes; de los cuales 64.83% en dientes anteriores, 63.83% en dientes posteriores, 74% en dientes maxilares y aproximadamente 74.5% en dientes mandibulares. Fue 100% prevalente en los grupos de edad 31-40 y 41-50, mientras que la prevalencia fue 67.2% en el grupo de edad 20-30. Esto demostró que la prevalencia del desgaste dental fue significativamente mayor en los dos grupos de personas mayores que en el grupo más joven (p<0.001). Además, mascar khat, la ubicación, el consumo muy frecuente de alimentos y la alta frecuencia de bebidas ácidas fueron indicadores críticos del desgaste dental. Además, el bajo nivel educativo, el tabaquismo y el bajo nivel socioeconómico se asociaron con el degaste dental. Finalmente, el estudio reveló que el desgaste dental es altamente prevalente entre los adultos en dos ciudades yemeníes, y los indicadores de riesgo socioconductual como la masticación de khat y el tabaquismo tienen una asociación significativa con el desgaste dental.

Phenotypic Demonstration of ß-lactamase (ESßLs, MßLs, and Amp-C) among MDR Pseudomonas aeruginosa isolates obtained From Burn wound infected in Yemen

In 2017, the World Health Organization published its first-ever list of antimicrobial-resistant bacteria “prioritypathogens,” a catalog of 12 families of bacteria posing the greatest threat to human health. This list focuses onthe risk of Gram-negative bacteria for multiple drug-resistant. Pseudomonas aeruginosa was at the top of the listand critical. A current study aiming to demonstrate the prevalence of β-lactamase among multidrug-resistant P.aeruginosa strains isolated from burn wound patients phenotypically. The isolates were identified then antibioticsusceptibility tested against 10 antipseudomonal agents, finally, phenotypically β-lactamase (ESβLs, MβLs, andAmp-C) production screened by combined disk diffusion test and Imipenem-ethylenediaminetetraacetic acid.Results in the current study identified 98 P. aeruginosa isolates from 200 clinical specimens obtained from burnwound patients. Our result showed 65 (66.3%) of the 98 P. aeruginosa isolates were multiple drug-resistant(MDR) strains. Out of 65 isolates, 37 (56.9%), 21 (32.3%), and 40 (61.5%) were ESβLs, MβLs, and Amp-Cproducing P. aeruginosa, respectively, according to phenotypic detection method. We found co-expression ofvarious β-lactamases. In the present study, 16 isolates showed co-existence of AmpC + ESBL, 16 isolates werehaving ESBL + MBL + AmpC, and five isolates were having co-existence of ESBL + MBL. The occurrence ofESβLs, MβLs, and Amp-C producing P. aeruginosa was demonstrated, calling for phenotypical determinationof antibiotic resistance mechanisms should be performed regularly to guide antibiotic selection during therapy.Significant conclusions drawn from this work include a rise in the rate of β-lactamase (ESβLs, MβLs, andAmp-C) in MDR P. aeruginosa. Later research should, therefore, focus on the study of molecular characterization.

Prevalence of impacted teeth among a sample of yemeni population and their association with sex and age / Prevalencia de dientes impactados entre una muestra de población yemení y su asociación con el sexo y la edad

Aim: the aim of the study was to assess the prevalence of impacted teeth and its association with sex and age among a sample of the Yemeni population. Materials and Methods: A cross sectional study design was employed. The study included 999 radiographical records of patients who had panoramic X- rays previously done. All radiographs were assessed for the number and type of impacted teeth, pathology-associated impaction, sex, age and location (mandible and/or maxilla). The collected data was analyzed using SPSS®version21 software. Results: The study sample comprised digital panoramic radiographs of Yemeni patients aged 17 to 54 years (mean 26.6 years). The present study found 542 patients (54.3%) presented with at least one impacted tooth. The 17 to 25 years age group of the study sample had the highest prevalence of tooth impaction (28.6%). Only 10 (1.0%) case presented pathologies associated with the impacted teeth. There was a significant difference in the number of male 203 (20.3%) and female 339 (33.9%) patients with impacted teeth (p=0.031). Impacted teeth occurred slightly more often in the mandible (42.8%) compared to the maxilla (42.4%). Conclusion: The prevalence of impacted teeth among a sample of Yemeni population was high. Third molars and canines were the most common impacted teeth. The prevalence of impacted teeth in females was higher than in males and it was higher in the mandible than in the maxilla, with the younger patients with a higher prevalence of impaction.

Objetivo: el objetivo del estudio fue evaluar la prevalencia de dientes impactados y su asociación con el sexo y la edad en una muestra de la población yemení. Material y Métodos: se empleó un diseño de estudio transversal. El estudio incluyó 999 registros radiográficos de pacientes con radiografías panorámicas realizadas previamente. Todas las radiografías fueron evaluadas en relación al número y tipo de dientes impactados, patología asociada a la impactación, sexo, edad y ubicación (mandíbula y/o maxilar). Los datos recopilados se analizaron utilizando el software SPSS® version 21. Resultados: La muestra del estudio comprendió radiografías panorámicas digitales de pacientes yemeníes entre 17 a 54 años (media 26,6 años). El presente estudio encontró que 542 pacientes (54,3%) presentaron al menos un diente impactado. El grupo de edad de 17 a 25 años de la muestra de estudio tuvo la mayor prevalencia de impactación dental (28,6%). Solo 10 casos (1,0%) presentaron patologías asociadas a los dientes impactados. Hubo una diferencia significativa en el número de pacientes masculinos 203 (20.3%) y femeninos 339 (33.9%) con dientes impactados (p=0.031). Los dientes impactados ocurrieron con un poco más de frecuencia en la mandíbula (42.8%) en comparación con el maxilar (42.4%). Conclusión: La prevalencia de dientes impactados entre una muestra de población yemení fue alta. Los terceros molares y caninos fueron los dientes más comúnmente impactados. La prevalencia de dientes impactados en las mujeres fue mayor que en los hombres y fue mayor en la mandíbula que en el maxilar, y los pacientes más jóvenes mostraron una mayor prevalencia de impactación.

First Evidence of West Nile Virus in Hodeidah, Yemen: Clinical and Epidemiological Characteristics

ntroduction:West Nile Virus (WNV) infection is an important arthropod-borne zoonosis viral disease. This virus is neglected in Yemen especially in Hodeidah.Aim of the Study:The purpose of this study was to detect WNV infection,determinethe epidemiological and clinical characteristics within febrile patients in Hodeidah city and to determine some risk factors associatedwith WNVinfection.Materials and Methods: 136 febrile patients in a hospital base study were diagnosed in Center of Tropical Medicine and Infectious Diseases (CTMID), Authority of General Al-Thawara Hospital Hodeidah, Yemen from January of 2017 to December of 2017. WNV infection was detected by enzyme linkage immune sorbent assay (ELISA) on serum samples. Results and Discussion:The results showed that 5 cases (3.67%) were WNV –positive namely IgM thatwas detected inwinter and spring seasons,the most prevalent antibodies of WNVwere IgG namely 75 cases (55.14%). Most common symptoms were fever, headache, fatigue, weakness, arthralgia, myalgiaand photophobia. The treatment based on the intravenoustherapy (IV)with anti-pyritic,plasma in some cases and all cases were recovered whilemortality rate was 00%. Conclusion:WNVwas detected in Hodeidah which placed in Tehama "western Yemen", as first time by our preliminary study that confirmed the evidence of WNV IgM and IG antibodies presence on 2017, in order to increase safety of diagnosis of febrile diseases, it is essential to continue surveillance of this emerging infection, suggesting that this emergence has been transported by migratory birds from winteringareas to Tehama region.

Hepatitis C Virus Among Health Care Workers And The Risk Factors Contributing For Its Infection

Back ground: Hepatitis C Virus (HCV) infection is one of the leading causes of morbidity and mortality in under-developed countries like Yemen. According to an estimate, 2.0 % of Yemeni's total population suffers from HCV infection which makes a total of 600,000 people. Hepatitis C has emerged as a big challenge for Yemen. Health care workers are at increased risk of being infected due to tremendous exposure. Objective: The purpose of this study was to nd the prevalence of hepatitis C, its risk factors contributing for infection among health care Workers at Sana'a City. Methods: Across sectional survey conducted among 345 health care workers in the main general hospitals and health centers in Sana'a City. Blood samples were collected, and HCV antibodies were measured by using both Enzyme Immunoassay (EIA) and Recombinant ImmunoBlot Assay (RIBA) Results:The prevalence rate of Hepatitis C virus among HCWs was 4.1%. Those who used needle cupping, needle stick injury, surgical operation, the rate was (8.7%), (4.9%) and (4.2%) respectively. Conclusion: The frequency of HCV among health care workers is high. Awareness programs, training and continuing education should be mandatory and establishment of a national policy roadmap to increase knowledge about hepatitis C prevention. It will decrease the incidence of hepatitis C infection among health care workers.

Risk factors associated with the recent cholera outbreak in Yemen: a case-control study / 한국역학회지

OBJECTIVES: The cholera outbreak in Yemen has become the largest in the recent history of cholera records, having reached more than 1.4 million cases since it started in late 2016. This study aimed to identify risk factors for cholera in this outbreak. METHODS: A case-control study was conducted in Aden in 2018 to investigate risk factors for cholera in this still-ongoing outbreak. In total, 59 cholera cases and 118 community controls were studied. RESULTS: The following risk factors were associated with being a cholera case in the bivariate analysis: a history of travelling and having had visitors from outside Aden Province; eating outside the house; not washing fruit, vegetables, and khat (a local herbal stimulant) before consumption; using common-source water; and not using chlorine or soap in the household. In the multivariate analysis, not washing khat and the use of common-source water remained significant risk factors for being a cholera case. CONCLUSIONS: Behavioural factors and unsafe water appear to be the major risk factors in the recent cholera outbreak in Yemen. In order to reduce the risk of cholera, hygiene practices for washing khat and vegetables and the use and accessibility of safe drinking water should be promoted at the community level.

Risk factors associated with the recent cholera outbreak in Yemen: a case-control study / 한국역학회지

OBJECTIVES: The cholera outbreak in Yemen has become the largest in the recent history of cholera records, having reached more than 1.4 million cases since it started in late 2016. This study aimed to identify risk factors for cholera in this outbreak.METHODS: A case-control study was conducted in Aden in 2018 to investigate risk factors for cholera in this still-ongoing outbreak. In total, 59 cholera cases and 118 community controls were studied.RESULTS: The following risk factors were associated with being a cholera case in the bivariate analysis: a history of travelling and having had visitors from outside Aden Province; eating outside the house; not washing fruit, vegetables, and khat (a local herbal stimulant) before consumption; using common-source water; and not using chlorine or soap in the household. In the multivariate analysis, not washing khat and the use of common-source water remained significant risk factors for being a cholera case.CONCLUSIONS: Behavioural factors and unsafe water appear to be the major risk factors in the recent cholera outbreak in Yemen. In order to reduce the risk of cholera, hygiene practices for washing khat and vegetables and the use and accessibility of safe drinking water should be promoted at the community level.

Are Married and Unmarried People Differ in their Perception and Attitude about Family Functioning and Wellbeing in Selected Governorates in Yemen?

Globally, there is a scale of views about family functioning and wellbeing with a great deal of conflicting evidence. In Yemen, conservative social traditions are the norms. Yemen has one of the highest population growth rate and the highest rate of unmet need for FP in the world. This study aimed to explore the perception and attitude about family functioning and attitude among married and unmarried people in selected Yemeni Governorates. The study was conducted in April–May 2014 through house to house community-based cross-sectional survey with a purposively selected sample in 21 districts in 3 Yemeni governorates. The target population was Yemeni citizens aged 15+ years present in households in the targeted districts at the time of data collection. Married and un married respondents were approached equally with a pre-tested questionnaire and only consented respondents were enrolled. Analysis was done using the statistical package for Social Sciences version 22. Differences between married and unmarried respondents was tested by Chi squared test (χ²). Statistical significance was set at p˂0.05. The study involved 2217 respondents. Married and unmarried respondents were not different in their perception and attitude regarding family size, the negative influence of large family size, the relation of family size to children education and age at marriage, and some economic aspects in relation to large family size. However, they differently perceive the meaning of the family; reasons for establishing not different the family and for having children; decision makers for continuation of children education; reasons for postponing marriage, the influence of having too male children on increasing family income and on boosting father’s prestige amongst others. In conclusion; married and unmarried were not different in most of the addressed issues. The few differently perceived issues reflect differences in life experience, reality and social responsibilities. There is a need for further studies to monitor practices related to demographic changes over time in the Yemeni society.

Prevalence of Internet Addiction and Its Associated Factors among Medical Students, Yemen

@#Problematic Internet addiction becomes one of the major problems in today's world. This study aimed to identify the prevalence of Internet addiction and its associated factors among medical students of University of Sciences and Technology.

Management of temporomandibular joint ankylosis in yemeni children by metatarsal bone grafts

Aim: This study aimed to evaluate temporomandibular joint reconstruction in Yemeni children with metatarsal bone graft after release of ankylosis. Methodology: Ten patients ≤12 years of age, comprising eight unilateral and two bilaterally TMJ ankylosis, were selected for this study. These patients underwent reconstruction with 10 non-vascularized metatarsal grafts. The reconstructed joints were then followed for an average of 1 year. Measures of opening, symmetry, and clinical symptoms relating to the reconstructed joints were assessed. Results: Mean pre-operative interincisal aperture was 8.2mm, and immediate post-operative aperture 23.4mm. At the end of the follow-up period, acceptable results were achieved in 8 out of 10 cases, with adequate mouth opening of 35.6mm in 8 out of 10 patients and overall interincisal aperture of 30.3mm. Re-ankylosis occurred in two bilaterally-treated patients at the end of follow-up. Subjectively, 80 percent of the patients rated their function as satisfactory and were able to occlude and masticate without any difficulty. Conclusion: Reconstruction of TMJ after release of ankylosis utilizing metatarsal bone graft shows a satisfactory interincisal aperture in 80 percent of patients.

Risk factors for periodontal diseases among Yemeni type II diabetic patients: a case-control study

BACKGROUND: chronic periodontal diseases are one of diabetes mellitus complications. The present study aims to compare the periodontal status of type II diabetic patients to a control group and assess the role of risk factors in both groups. MATERIALS AND METHODS: A case-control study was conducted of 270 individuals (132 type II diabetics and 138 non-diabetics). Full mouth periodontal examination including plaque index, gingival bleeding, gingival recession, clinical attachment loss (CAL), tooth mobility, furcation involvement and the number of missing teeth. The case group was subdivided according to glycosylated hemoglobin (HbA1c) status (poorly controlled HbA1c >8 and well controlled HbA1c≤8) Likewise, the duration of diabetes mellitus as short or long duration (DM≤10 or >10). The diabetic group was also subdivided according to smoking and Khat chewing habits. RESULT: The severity of periodontal disease among type II diabetic patients were significantly higher compared to the control group regarding the plaque index 2.6 (1.6-4.3), bleeding on probing 3.5 (2.3-13.0), gingival recession 2.0 (1.2-3.4), furcation involvement 4.0 (2.3-6.7), clinical attachment loss 5.7 (3.1-10.5), tooth mobility 2.0 (1.2-3.4), and number of missing teeth 4.4 (2.3-8.5). In addition, poorly controlled type II DM and long duration had higher CAL and number of missing teeth than well-controlled DM and short duration. No significant differences were found between smokers/nonsmokers and Khat chewers/non-chewers among the diabetic group. CONCLUSION: Type II diabetic patients have severe periodontal destruction and tooth loss compared to non-diabetic people and there were no differences within the diabetic group in regards to smoking and Khat chewing habits.(

Cross-sectional assessment of the periapical status as related to quality of root canal fillings and coronal restorations in a Yemeni population

Aim: the present study aimed to examine the influence of the quality of root canal fillings and coronal restorations on the prevalence of periapical lesions. Materials and Methods: Two hundred digital panoramic radiographs were obtained from the archive of Al‑HamziDental Center in Sana’a, Yemen. The final sample consisted of 120 radiographs, and 675 root filled teeth.The quality of root canal fillings was scored according to criteria of length, homogeneity and taper. Coronal status (type of restoration, signs of marginal leakage or decay) was also evaluated. The periapical status was categorized on the basis of presence or absence of radiographical signs of apical periodontitis. Chi-square test was used to determine statistical significance between different parameters. Results: We found that 93.6 percent of root filled teeth were associated with apical periodontitis. Only 9.2 percent of root filled teeth were found to have an acceptable standard of root canal fillings, of which 32.3 percent was also associated to signs of periapical disease. In roots with an unacceptable root canal filling, 95.4 percent had periapical disease. Teeth with good (14.4 percent) and poor (32.9 percent) intra-coronal restorations had apical periodontitis in 93.8 percent and 97.7 percent of cases, respectively. Crown restorations were present in 52.7 percent of root filled teeth, of which 91.0 percent were associated with periapical lesions. Conclusion: The poor technical quality of root canal fillings and coronal restorations is consistent with a high prevalence of apical periodontitis.