ABSTRACT
Depression is a kind of emotional and mental disorder， which is related to many pathogenic factors， such as abnormal metabolism of monoamine neurotransmitters， immune inflammatory reaction， neuroendocrine disorder and so on. it has the characteristics of high disability rate and high recurrence rate， which is seriously harmful to human health. It brings huge economic burden to patients and their families. At present， the commonly used antidepressants in clinic are monoamine oxidase inhibitors， tricyclic antidepressants and selective 5-hydroxytryptamine reuptake inhibitors. Long-term use causes adverse reactions such as cardiovascular， urinary and digestive dysfunction. The multi-target， multi-pathway and multi-mechanism of traditional Chinese medicine has played a great role in the treatment and rehabilitation of depression. At the same time， traditional Chinese medicine has gradually become a hot spot in the research and development of antidepressants because of its small side effects and good drug compliance. Especially the ZHANG Zhong-jing's classical formulae with precise medication and rigorous prescription has unique advantages in the treatment of depression. For thousands of years， it has been used clinically by countless doctors in the treatment of various types of depression， with definite curative effects and few side effects. In recent years， clinical research， experimental research， and pharmacological research around ZHANG Zhong-jing's classical formulae for depression have been continuously expanded and deepened. This article reveals the rules of medication of the treatment of depression with ZHANG Zhong-jing's classical formulae from three aspects of Bupleurum class prescription， Gardenia class prescription， and other prescriptions， which is reflected in the study on the composition of prescription， the etiology， and pathogenesis and the symptoms of the treatment. Integrating and classifying ZHANG Zhong-jing's classical formulae's experience in the treatment of depression， mainly expounded from two aspects， clinical research and pharmacological research， summarizing the research perspective and progress of Zhongjing prescription medicine in the treatment of depression in recent years， to excavate， inherit and develop ZHANG Zhong-jing's classical formulae， and provide experience and reference for the treatment of depression from multiple angles and ideas.
ABSTRACT
According to ZHANG Zhong-jing, the main reason for the stroke was the exogenous wind, and the most important pathogenesis was the deficiency of qi and exogenous pathogenic factor. Three methods are stressed to cure the stroke: the equal treatment focused on the liver and the spleen, the use of tranquilizing medicine to stop the wind, and the use of strengthening body resistance to get rid of the exogenous pathogenic factors. While YE Tian-shi considered that the main reason for stroke was the deficiency of liver-yin and kidney-yin. The chief pathogenesis in stroke was the yang transforms to the interior wind. There are three therapeutic features in the treatment: the equal treatment focused on the liver and the spleen, the synchronous treatment of the liver and stomach, and select the medicine according to the four seasons climate. ZHANG Zhong-jing's theory of exogenous wind and YE Tian-shi's theory of yang transforms to the interior wind not only reflect the different angles in treatment for stroke, but also reflect the development of pathogenesis of stroke in the history.
ABSTRACT
Objective] Make a research on curative properties from the aspect of zang-fu differentiation in dysuria of Zhang Zhong-Jing. [Methods] Detailly discussed about the properties of dysuria from five aspects: lung, spleen, kidney, triple energizer and bladder. Combine these factors with articles in Treatise on Exogenous Febrile Disease to estimate the condition of body fluid and prognosis of the disease. [Results]The several methods to diagnose and treat dysuria from the idea of Zang-fu Theory, such as ventilating lung and relieving the exterior, invigorating spleen and dissipating excessive fluid, purging and benefiting triple energizer, warming kidney and transforming qi, promoting urination and activating yang. Smooth or not of urine could help to locate the lesion viscera, determine the attribute of deficiency and excess of etiology and judge the prognosis of diseases. [Conclusion]Zhang Zhong-Jing ’s Zang-fu syndrome differentiation theory is an effective way to diagnose and cure dysuria in clinical practices, it is worthy of further research.
ABSTRACT
Wiry pulse is one of the common pulse tracings, which was recorded firstly in Inner Canon of Huangdi. Most of the modern textbooks of diagnostics of TCM consider that it relates with liver-gallbladder diseases, ache and phlegm-fluid retention,etc. However, there was not record of stringy pulse relating with liver-gallbladder diseases in Treatise on Cold Pathogenic Diseases. From the original of ZHANG Zhong-jing, this article researched the author’s object of discussing stringy pulse, which can be induced as three aspects: diagnosing diseases, analysing pathogenesis and deducing prognosis. The anticle maybe benefi ted to clinical work of TCM.
ABSTRACT
In terms of drugs' concerted application regulation,this article studies usage of drugs in different prescriptions in ZHANG Zhong-jing's Treatise on Cold Pathogenic Diseases and Synopsis of Golden Chamber,and summarizes various drugs' concerted application as follows: First,composite of mutual promotion between two drugs in similar properties;Second,composite of several drugs in same flavour;Third,composite of fusion of flavors and drugs;Fourth,composite of drugs available in same nature;Fifth,composite of drugs in cold and hot nature;Sixth,composite of tonic and laxative;Seventh,composite of the use of mutual assistance between drugs in different properties;Last,composite of change of drugs according to different syndromes.Also,the article,integrating with Zhong-jing's prescriptions,discusses the different concerted apllication above in detail.
ABSTRACT
A large amounts of information related to Jiangxi Treatment is contained in Treatise on Febrik and Miscellaneous.This paper expounds four aspects of ZHANG Zhong-jing's medical thought:decocting,taking medicine,improving conditions and preserving health after administration.The paper also points out the enlightening in uence of these medical thought on the physicians of later generations.