Study on Improvement of Zea mays Extract on Cholestatic Liver Diseases / 中国药房

OBJECTIVE:To study the improvement of Zea mays extract on cholestatic liver diseases.METHODS: Acute cholestatic liver injury model of rat was induced by bile duct ligation and cholestatic liver model of rats was established by ANIT.Model rats were given 6.2 g?kg-1 and 3.1 g?kg-1 dose of Z.mays extract for 5 days.The content of TBIL,DBIL,ALT,AST and TBA in serum and the secretion of bile were determined.RESULTS: The corn stigma extract decreased the content of DBIL,ALT and TBA in serum of ANIT-inducing cholestatic liver model,and increased the flow and speed of bile (P