ABSTRACT
Zosteriform metastasis from malignant melanoma is a rare type of skin metastasis that shows cutaneous lesions including patches, plaques, and nodules along with dermatomes, and thus needs to be distinguished from herpes zoster skin infection. Although some authors have explained the mechanism of zosteriform metastasis, its pathogenesis remains unknown. Herein, we describe an 85-year-old woman with zosteriform metastasis of malignant melanoma arising in a medium-sized congenital melanocytic nevus.
Subject(s)
Aged, 80 and over , Female , Humans , Herpes Zoster , Melanoma , Neoplasm Metastasis , Nevus, Pigmented , SkinABSTRACT
Skin metastases from internal malignancies are rare and have been reported in 0.7~9% of malignancies, most commonly from carcinomas of the breast, lung, colon, kidney, stomach, and melanoma. The common clinical manifestations of cutaneous metastases are nodular, inflammatory and sclerodermoid metastatic lesions. Other manifestations of skin metastasis include neoplastic alopecia, acute dermatitis like, en cuirasse, carcinoma erysipelatoides, carcinoma telangictatoides, and zosteriform. Zosteriform cutaneous metastases are very rare and may demonstrate vesicobullous, papular, and nodular lesions. In the previous reports, zosteriform metastasis was associated with melanoma, lymphoma, breast cancer, squamous cell carcinoma, colorectal carcinoma, respiratory carcinoma, and urinary tumors. We report the first case of a zosteriform cutaneous metastasis from a gastric adenocarcinoma in the Korean literature.
Subject(s)
Adenocarcinoma , Alopecia , Breast , Breast Neoplasms , Carcinoma, Squamous Cell , Colon , Colorectal Neoplasms , Dermatitis , Kidney , Lung , Lymphoma , Melanoma , Neoplasm Metastasis , Skin , StomachABSTRACT
Cutaneous metastases from internal malignancies are uncommon and a zosteriform pattern is very rare. Malignancies with zosteriform cutaneous metastases have their origin from skin cancers, vascular tumors, hematologic malignancies, and visceral neoplasia. We present the case of a 44-year-old female with zosteriform metastasis secondary to breast carcinoma. In our case, as in some of the cases from the literature, the patient was initially misdiagnosed clinically as having herpes zoster. Moreover, herpes viral infections are common in immunosuppressed patients and must be ruled out.