ABSTRACT
Objective To investigate the effect of conventional western medicine on children with acute nephritis on the basis of the use of methylprednisolone and psychological intervention on the curative effect of children. Methods A total of 300 patients with acute nephritis were selected from March 2014 to March 2017. The patients were divided into study group and control group by random number table. The control group on the basis of conventional western medicine plus methylprednisolone, study group were treated with methylprednisolone and psychological intervention on the basis of conventional western medicine, observe the clinical efficacy of two groups of children with acute nephritis. Results After treatment, the total effective rate of clinical treatment was 88.67% in the study group, which was significantly higher than that in the control group (72.00%), the difference was statistically significant (P<0.05). Conclusion The application of routine western medicine treatment of acute nephritis in children on the basis of if the children plus methylprednisolone, psychological intervention can significantly improve clinical efficacy, are of positive significance to guarantee the quality of life, physical and mental health of children.
ABSTRACT
Objective To investigate the effect of conventional western medicine on children with acute nephritis on the basis of the use of methylprednisolone and psychological intervention on the curative effect of children. Methods A total of 300 patients with acute nephritis were selected from March 2014 to March 2017. The patients were divided into study group and control group by random number table. The control group on the basis of conventional western medicine plus methylprednisolone, study group were treated with methylprednisolone and psychological intervention on the basis of conventional western medicine, observe the clinical efficacy of two groups of children with acute nephritis. Results After treatment, the total effective rate of clinical treatment was 88.67% in the study group, which was significantly higher than that in the control group (72.00%), the difference was statistically significant (P<0.05). Conclusion The application of routine western medicine treatment of acute nephritis in children on the basis of if the children plus methylprednisolone, psychological intervention can significantly improve clinical efficacy, are of positive significance to guarantee the quality of life, physical and mental health of children.
ABSTRACT
Focal acute nephritis (FAN) or acute lobar nephronia is a rare clinical picture characterized by an infection localized in the kidney, with an inflammatory mass without liquefaction. Of variable clinical manifestations, diagnosis is achieved through CT scanning. Histologically, unlike acute pyelonephritis, it does not present a diffuse infíltrate. Objective: Case report of FAN in a pediatric patient. Case Report: Ten year old male complaining of abdominal pain, presents painful percussion in the right lumbar fossa. Urinary analysis and culture were negative, renal sonogram was negative. Abdominal CT sean showed múltiple hypodense renal foci. He responded well to cephotaxim, being discharged in the third day of hospitalization with completion of treatment as outpatient. Differential diagnosis with Acute Pyelonephritis is very important, as it requires controlled and opportune treatment to prevent renal absceses. Diagnosis of this pathology must be pursued despite a normal UA.
La nefritis aguda focal o nefronia lobar aguda constituye un cuadro poco común caracterizado por una infección localizada en el riñon, la que corresponde a una masa inflamatoria sin licuefacción. Posee una clínica variable, siendo la tomograña computada (TAC) la prueba más sensible y específica para el diagnóstico de esta enfermedad. Esta patología se diferencia histológicamente de la pielonefritis aguda por no presentar un infiltrado inflamatorio difuso. Objetivo: presentar un caso de nefronia aguda multifocal en un paciente pediátrico. Caso clínico: Escolar de 10 años que consultó por dolor abdominal, al examen destacaba la presencia de percusión dolorosa en fosa lumbar. Los exámenes de orina y urocultivo fueron negativos. Al ingreso no se detectó cambios renales ecográficamente evidenciables. Se realizó un TAC de abdomen que mostraba múltiples focos renales hipodensos. Respondió favorablemente a terapia antibiótica con cefotaxima siendo dado de alta al tercer día, completando terapia en forma ambulatoria. La diferenciación de este cuadro de otros procesos renales como la pielonefritis aguda (PNA) es muy importante, ya que precisa un tratamiento oportuno y controlado por el riesgo de evolucionar a absceso renal. El diagnóstico de esta patología debe ser buscado a pesar de contar con exámenes de orina negativos.
Subject(s)
Humans , Male , Child , Urinary Tract Infections/etiology , Nephritis/complications , Nephritis/diagnosis , Acute Disease , Anti-Bacterial Agents/therapeutic use , Cefadroxil/therapeutic use , Cefotaxime/therapeutic use , Urinary Tract Infections/drug therapy , Nephritis/drug therapyABSTRACT
PURPOSE: Henoch-Sch nlein purpura(HSP) is a common pediatric disease presenting most frequently with skin, gastrointestinal, joint and renal manifestations. The prognosis of HSP is mainly determined by the involvement of the kidney, but prognostic markers have not been established. We evaluated the patients who have HSP nephritis with nephrotic syndrome. METHOD: Clinical manifestations and laboratory findings were observed and analyzed in 34 cases with HSP which were manifested by nephrotic syndrome, hospitalized at Kyung Hee university Hospital during the period from Jan. 1990 to Dec. 1998. RESULTS: 1) Male to female ratio was 1.3:1, and mean age at onset was 8.3 year. 2) Mean duration from symptom onset to renal biopsy was 10.5 weeks. 3) Proportion of patients presenting with acute nephritis was 32.4%, gross hematuria 17.6%, microscopic hematuria 50%. 4) The findings of renal biopsy were 20 cases of grade II, 11 cases of grade III, 2 cases of grade I, 1 case of grade IV according to classification by ISKDC. 5) Patients with grade I were recovered with no residual defect, but patients with grade IV shows active renal disease(states C). CONCLUSION: Among the patients with Henoch-Sch nlein purpura accompanying nephrotic syndrome, more aggressive treatment might be needed in patients showing crescents formation on renal biopsy. A prospective study will be needed to explore the progression of this disease.