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1.
Chinese Journal of Biochemical Pharmaceutics ; (6): 51-53, 2017.
Article in Chinese | WPRIM | ID: wpr-613946

ABSTRACT

Objective To investigate effect of BCG polyose nuclear acid combined with adapalene Gel in the treatment of flat wart.MethodsFrom January 2015 to May 2016, 100 flat wart patients were selected in our hospital, the patients were divided into observation group and control group, each group 50 cases, the control group was given Adapalene Gel therapy, the treatment group was treated with BCG polyose nuclear acid on the basis of control group, the therapeutic effect of the two groups were observed.ResultsThe total effective rate of the treatment group was 84.0%(42/50), and the control group was 60.0%(30/50)The treatment effect of observation group was significantly better than the control group (P< 0.05);The skin lesion score of observation group after treatment was (4.22±1.05) scores, which was significantly lower than that in the control group (P< 0.05);There was no significant difference in T lymphocyte subsets between the observation group and the control group;After treatment, the lgG and lgM in observationgroup were higher than before treatment (P< 0.05);The adverse reaction rates of the observation group and the control group were 14.0%(7/50) and 18.0%(9/50), the difference was not statistically significant.ConclusionThe therapeutic effect of BCG polyose nuclear acid combined with adapalene gel in the treatment of flat wart is better, it can improve the humoral immune function of patients, and it is safe and reliable.

2.
China Pharmacy ; (12)2007.
Article in Chinese | WPRIM | ID: wpr-534382

ABSTRACT

OBJECTIVE:To observe the clinical efficacy of Xinhuang tablets combined with Azithromycin granules and 0.1% Adapalene gel in the treatment of acne vulgaris.METHODS:216 patients with acne vulgaris were randomly divided into experimental group and control group according to visiting order (n=108).Experimental group were treated with oral administration of Xinhuang tablets and Azithromycin granules and 0.1% Adapalene gel for external use.Control group were treated with Erythromycin enteric-coated tablets and Compound sulfur lotion.Clinical efficacies of 2 groups were observed after 6 weeks.RESULTS:Total effective rate was 97.2% for experimental group and 41.6% for control group.There was significant difference between 2 groups (P

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