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@#AIM:To evaluate the effect of Yangxue Runmu formula combined with sodium hyaluronate on dry eye after cataract surgery by ocular surface analyzer.<p>METHODS: Totally 80 patients with dry eye after cataract surgery in our hospital from June 2019 to December 2020 were selected and divided into control group and observation group by random number table method, 40 cases in each group. The control group was treated with sodium hyaluronate eye drops, and the observation group was treated with Yangxue Runmu formula combined with sodium hyaluronate eye drops. The index levels of ocular surface analyzer and fluorescein staining(FL)score were compared between the two groups.<p>RESULTS: After treatment, the wet length of tear film, first non-invasive tear break-up time(NIBUTf), average non-invasive tear break-up time(NIBUTav)and tear meniscus height(LTMH)in the two groups were markedly higher than those before treatment(all <i>P</i><0.01), and the observation group were markedly higher than those in the control group(<i>P</i><0.05); after treatment, the conjunctival hyperemia score, meibomian gland loss score, FL score in the two groups were markedly lower than those before treatment(all <i>P</i><0.01), and the observation group were markedly lower than those in the control group(all <i>P</i><0.01); there were no obvious adverse reactions in the two groups. <p>CONCLUSION: Through the evaluation and analysis of ocular surface analyzer, Yangxue Runmu formula combined with sodium hyaluronate can effectively improve the ocular surface function of patients after cataract surgery, and has good safety.
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@#AIM: To systematically evaluate the efficacy of sodium hyaluronate combined with recombinant human epidermal growth factor(rhEGF)eye drops in the treatment of dry eye after cataract surgery in recent 5a by Meta-analysis.<p>METHODS: The databases of CNKI, WanFang, Chongqing VIP, CBM, Cochrane Library, Pudmed and MEDLINE from January 2015 to May 2020 were searched. Meta analysis and statistical analysis were performed with Revman 5.3 software on the clinical control study of sodium hyaluronate eye drops combined with rhEGF eye drops in the treatment of dry eye after cataract surgery.<p>RESULTS: A total of 14 randomized controlled trials involving 1 529 eyes were included. Among them, 14 studies conducted corneal fluorescein staining(FL)score after the end of treatment, the results showed that the difference was statistically significant \〖<i>MD</i>= -0.86, 95%<i>CI</i>(-1.07 to -0.66), <i>P</i><0.00001\〗; 14 studies conducted tear film break-up time(BUT)measurement after the end of treatment, the results showed that the difference was statistically significant \〖<i>MD</i>=2.33, 95%<i>CI</i>(1.64, 3.03), <i>P</i><0.00001\〗, 95%<i>CI</i>(1.76 to 2.15), <i>P</i><0.00001\〗; tear secretion test(S I t)was measured in 12 studies after treatment, and the results showed that there was no significant difference \〖<i>MD</i>=0.49, 95%<i>Cl</i>(-0.52, 1.50), <i>P</i>=0.34\〗; the overall effective rate was calculated in 12 studies after treatment, and the results showed that the difference was statistically significant \〖<i>OR</i>=4.88, 95%<i>Cl</i>(3.34, 1.50), <i>P</i>=0.34\〗. The results showed that the difference was statistically significant \〖<i>MD</i>= -1.09, 95%<i>Cl</i>(-1.58, -0.61), <i>P</i><0.00001\〗.<p>CONCLUSION: Sodium hyaluronate combined with rhEGF eye drops in the treatment of dry eye after cataract surgery can significantly improve the corneal repair ability and tear film BUT, which has more advantages in the overall efficacy of the treatment of dry eye after cataract surgery.
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@#AIM:To observe the effects of recombinant human epidermal growth factor(rhEGF)eye drops on xerophthalmia after cataract surgery and its influence on tear film stability.<p>METHODS: The clinical data of 114 patients(158 eyes)with xerophthalmia after cataract surgery were retrospectively analyzed. According to the treatment methods of xerophthalmia, the patients were divided into study group(rhEGF+sodium hyaluronate group)and control group(sodium hyaluronate group). After 4wk of treatment, the efficacy and dry eye symptoms(dry eye questionnaire)were evaluated, and the BUT, SⅠt and FL were examined. The levels of IL-1β, IL-6 and TNF-α in tear were detected.<p>RESULTS: The total effective rate in study group was greater than that in control group(<i>P</i><0.05). After 4wk treatment, the BUT and SⅠt in the two groups were higher than those before treatment, and the indexes in study group were higher than those in control group(<i>P</i><0.01). The dry eye questionnaire score and FL and levels of tears IL-1β, IL-6 and TNF-α were lower than those before treatment, and the indexes in study group were lower than those in control group(<i>P</i><0.05).<p>CONCLUSION: Addition of rhEGF eye drops for xerophthalmia after cataract surgery can significantly improve dry eye symptoms, tear film stability, tear secretion and corneal epithelial cell integrity, and reduce inflammatory response, and it has significant efficacy.
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To investigate the utility of optomap panoramic 200Tx in screening fundus disease among the patients after cataract surgery. ●METHODS: From November 18 th to December 31st , 2013 all 146 post- cataract surgery patients were recruited. All non - mydriatic fundus images were taken with the optomap panoramic 200Tx and were diagnosed by one masked retinal specialist. Non - mydriatic direct ophthalmoscope exam and mydriatic slit-lamp lens exam were also done by other two masked specialists. Comparisons of the three methods were made. ●RESULTS: Among 146 patients ( 161 eyes), 40 eyes (24. 8%) of retinal lesions was detected by non-mydriatic direct ophthalmoscope exam, 59 ( 36. 7%) by non -mydriatic optomap 200Tx exam, and 61 (37. 9%) by slit-lamp lens exam. Nine eyes ( 5. 6%) needed medical intervention immediately. Results of optomap 200Tx exams and slit - lamp lens exams were similar without statistically significant difference ( P > 0. 05), better than direct ophthalmoscope exam ( P ● CONCLUSlON: Opacification of the refractive medium makes thorough fundus examination impossible. So post-operative fundus examination is highly necessary and should be a routine. Optomap panoramic 200Tx, which shows no statistically difference from mydriatc slit- lamp lens exam, is a convenient and feasible method in discovering fundus pathological changes.
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PURPOSE: To report the clinical outcomes and utility of 23-gauge (G) transconjunctival sutureless vitrectomy (TSV) in patients with postoperative endophthalmitis following cataract surgery. METHODS: The medical records of 16 patients (17 eyes) who underwent 23-G TSV between January 2008 and December 2009 at Konyang University Hospital due to postoperative endophthalmitis following cataract surgery were retrospectively analyzed. The pre- and post-operative best-corrected visual acuities (BCVA), changes in intraocular pressure, the time from diagnosis to surgery, the intraoperative and postoperative complications, and the average duration of hospitalization were investigated. RESULTS: The mean BCVA significantly improved from log MAR 1.89 +/- 1.03 to log MAR 0.42 +/- 0.82 (p = 0.001), and the mean intraocular pressure changed from 16.1 +/- 4.1 mm Hg at baseline to 16.2 +/- 3.3 mm Hg on the first postoperative day without any significant difference (p = 0.955). In addition, none of the patients required sutures to treat wound leakage or showed hypotony on follow-up observation. The average operation time was 64.7 +/- 22.5 minutes, and the average duration of hospitalization was 5.4 +/- 4.5 days. CONCLUSIONS: The use of 23-G TSV in patients with postoperative endophthalmitis following cataract surgery may offer more convenience for the surgeon and more comfort for the patient. In addition, the patient may return to normal life earlier with a shortened duration of hospitalization.
Subject(s)
Humans , Cataract , Endophthalmitis , Follow-Up Studies , Hospitalization , Intraocular Pressure , Medical Records , Postoperative Complications , Retrospective Studies , Sutures , Visual Acuity , VitrectomyABSTRACT
We reviewed our medical records to evaluate the incidenee of and risk factors for retinal detachment after cataract surgery according to the surgical methods. Group 1 included 605 eyes operated on with corneoscleral incision, extracapsular cataract extraction(ECCE) and posterior chamber intraocular lens(PCL) implantation, and Group 2 included 600 eyes with scleral tunneling incision, phacoemulsification and PCL implantation. 8 eyes(1.3 %) developed retinal detachment in group 1, whereas 1 eyes(0.2%) in group 2. The difference in incid ence between the two groups was statistically significant(P<0.05). Axial length is longer than 25mm, intraoperative posterior capsule rupture, and scleral fixation were identified as risk factors for retinal detachment after cataract surgery. From the above results, suggest that phacoemulsification with scleral tunnel incision is preferable to extracapsular cataract extraction(ECCE) with cornea-scleral incision, in cataract surgery, to lower the post operative complication of retinal detachment.