ABSTRACT
Objective:To investigate the stability of anterior chamber following implantable collamer lens (ICL) V4c implantation for one year in moderate and high myopic eyes.Methods:An observational case series study was conducted.Medical data of 19 patients (37 eyes) who received ICL V4c implantation in Xuzhou First People's Hospital from March 2016 to October 2017 were collected.The patients were 20 to 29 years old, with the preoperative spherical equivalent (SE) of -5.875 to -15.750 D, with an average of (-9.743±3.220)D.All eyes were followed up for one year, and the changes of visual acuity, SE and intraocular pressure were observed.Pentacam anterior eye segment analyzer was used to measure the anterior chamber depth (ACD), anterior chamber volume (ACV) and anterior chamber angle (ACA) before operation and at 1 month, 6 months and 1 year after operation, and to evaluate the vaults of the ICL V4c at different time points after implantation.This study protocol adhered to the Declaration of Helsinki and was approved by an Ethics Committee of Xuzhou First People's Hospital (No.xxy11[2015]-XJS-004). Written informed consent was obtained from each subject.Results:There were statistically significant differences in visual acuity between before and after operation ( F=5.057, P=0.007), and the one-year postoperative uncorrected visual acuity (UCVA) was significantly better than the best corrected visual acuity (BCVA) before operation ( P<0.05). There were no significant differences in SE and intraocular pressure among different time points ( F=1.294, 1.302; both at P>0.05). There were significant differences in ACD, ACV and ACA among different time points ( F=44.811, 889.971, 196.096; all at P<0.001). ACD, ACV and ACA at 1 month, 6 months and 1 year after operation were significantly lower than those before operation (all at P<0.001). There was a significant difference in the 1-month, 6-month and 1-year postoperative ICL vault ( F=7.256, P=0.001). The ICL vault at 1 year after operation was (433.784±168.550)μm, which was significantly decreased in comparison with (484.860±183.634)μm at 1 month and (464.351±170.167)μm at 6 months after operation ( P=0.006, 0.041). Conclusions:The anterior chamber is stable in one year after ICL V4c implantation, and the UCVA is better than preoperative BCVA.ICL V4c is safe and effective for moderate and high myopia.
ABSTRACT
@#AIM: To evaluate the changes of anterior chamber structure in patients after combined surgery of glaucoma and cataract with viscoelastics injection under the sclera valve by OCT. <p>METHODS: The cataract with acute glaucoma patients who underwent combined surgery of glaucoma and cataract from 2016 to 2018 were enrolled. The patients were divided into the viscoelastics group and the control group. The anterior chamber depth(ACD), the angle opening distance(AOD<sub>500</sub>)and the trabecular iris angle(TIA)were examined to compare the changes of the anterior chamber structure between the two groups. <p>RESULTS: At 1 and 3d after surgery, the ACD(3.82±0.51,3.71±0.63, 3.78±0.33mm), the angle opening distance(AOD<sub>500</sub>: 0.25±0.04, 0.24±0.04, 0.25±0.05mm)and the TIA(25.13°±8.06°, 26.18°±8.06°, 29.25°±6.22°)were statistically different between two groups. There was no significant difference on the ACD, the AOD<sub>500</sub> and the TIA of the two groups 7d after surgery(<i>P</i><0.05).<p>CONCLUSION: Viscoelastics injection under the sclera valve can deepen the anterior chamber effectively after combined surgery of glaucoma and cataract. It avoids the occurrence of shallow anterior chamber in the early postoperation and maintains the opening of anterior chamber.