Randomized, assessor-blind, controlled clinical trial on the efficacy and safety of aromatic oil (10% eucalyptus oil, 10% lavender oil, 10% rosemary oil) shampoo versus 1% permethrin shampoo in the treatment of pediculosis capitis

BACKGROUND: Permethrin shampoo is currently the first-line treatment for pediculosis capitis. However, its widespread use has resulted in the development of resistance.OBJECTIVE: To compare aromatic oil shampoo and 1% permethrin shampoo in terms of efficacy and safetyMETHOD: One hundred fifty-hour patients with active infestation were treated in this randomized, assessor-blind, controlled trial using aromatic oil or permethrin shampoo, applied once weekly for three weeks. Evaluations were conducted at baseline and a week after shampoo application. Complete cure was defined as the absence of live louse on day 21.RESULTS: There were no significant differences between the two groups in terms of complete cure, changes in patient's quality of life and pruritus at day 21. Neither group reported any diverse effects.CONCLUSION: The efficacy and safety of the aromatic oil shampoo was comparable to that of 1%permethrin shampoo in treating pediculosis capitis.

Contribution to study on the chemical components of aromatic oil of Hoang lan (Cananga odorata (lamb) hook F. et thomas. Annonaceae in Vietnam

In this study, the flower essential oil from Cananga odorata (Lamb.) Hook f.et Thomas, Annonaceae, of Vietnam was studied by GC and GC-MS,IR.20 components of the oil, intotal amounting to 93.3%, were identified. Linalool (21.3%), geranyl acetate (6.2%), -caryophyllene (7.3%), -cubebene+ germacrene D+g-cadinene (27.8%) and benzylbenzoate (13.4%) were the major components of the oil.

Chemical components of aromatic oil from branches with leaves and flower of com-ruou (glycosmis pentaphylla (Retz.), Corr in Vietnam

Glycosmis pentaphylla is a shrub 4-5m high, leaflets 2-5, white flower, fruit around. It is distributed in edge of forest in North midland area of Vietnam. The oil yield was 0.3% from branch with leaves and flower by air-dry material. The essential oil of Glycosmis pentaphylla was analyzed by GC/MS, 88 constituents have been identified. Major constituents were: alpha-pipene (27.1%); beta-caryophyllene (10.3%); spathulenol (7.7%); caryophyllen oxid (7.3%) and aromadendren 6.4%.

Improvement of equipment for quantifying aromatic oil in medicinal plants

The new apparatus is improved on the base of the apparatus for volatile oils determination of the “Methode I” described in the Vietnamese Pharmacopeia I (1971). It includes in 3 principal parts: a shortneck 0.5-1 liter flask, a cold condenser and a tube adapter, which binds the flask and a condenser. Tube florentin, which is suspensed in the tube adapter, is graduated in 2 parts: the superior part to 0.1ml and the inferior part (smaller) to 0.02ml. The improved apparatus is simple, good closed and permit to determine exactly the volatile oils in the drugs.