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1.
Indian J Ophthalmol ; 2019 Jun; 67(6): 940-942
Article | IMSEAR | ID: sea-197300
2.
Indian J Ophthalmol ; 2019 Jun; 67(6): 846-853
Article | IMSEAR | ID: sea-197277

ABSTRACT

Purpose: To use the extent of retinal immaturity at the first visit to predict progression to any stage and treatment-requiring retinopathy of prematurity (ROP). Methods: Retrospective, multicenter, nonrandomized, observational, clinical, validation study. In all, 601 Asian Indian preterm infants born < 2000 g and/or < 34 weeks of gestation completing ROP screening with RetCam images taken during each visit were included. A total of 1202 eyes of these infants were classified into three groups based on the retinal immaturity at the first screening visit into “mild” (Group 1), vessels reaching the posterior boundary of zone 3; “moderate” (Group 2), vessels entering zone 2 anterior; and “severe” (Group 3), vessels in zone 1 or zone 2 posterior. RetCam images at each subsequent visit were evaluated and the proportion of eyes that progressed to Type 1 or Type 2 ROP was correlated with the degree of retinal immaturity. Results: Of the 958 eyes in Group 1, 200 eyes in Group 2, and 44 eyes in Group 3, any stage ROP developed in 15% of eyes in Group 1, 46.5% of eyes in Group 2, and 100% of eyes in Group 3 (P < 0.001). Sixteen of 128 eyes (12.5%), 12 of 72 (16.6%), and 28 of 44 of eyes (63.6%) in Groups 1, 2, and 3, respectively, required treatment (P < 0.001). Conclusion: Retinal immaturity at first screening visit predicts Type 1 and Type 2 ROP. “Severe” immaturity is more likely to progress to “treatment-requiring” disease. This could be a useful tool for prognostication, counseling, and scheduling follow-up.

3.
Journal of the Korean Ophthalmological Society ; : 1823-1830, 1998.
Article in Korean | WPRIM | ID: wpr-27618

ABSTRACT

The retinal vascular changes and the results of treatment were studied in five incontinentia pigmenti patients. All patients were female and had a mean follow-up of 4 1/2 years (7 months~7 1/2 years). Abnormal retinal vascular changes included peripheral avascular retina, retinal and preretinal neovascularization, and dilated, tortuous retinal vessels. Two of them were treated; one received a cryotherapy and the other a laser photocoagulation to the avascular retinal area and showed regression of abnormal vessels. At last follow-up, no eye developed retinal detachment, but traction of the peripheral retina by a vitreous band was visible in three patients. One showed a degenerative macula and an atrophy of the retinal pigment epithelium in the papillomacular bundle area. Our result suggests that incontinentia pigmenti eyes may show retinal vascular changes very similar to that in retinopathy of prematurity, and can be effectively treated by destroying an avascualr retina if indicated.


Subject(s)
Female , Humans , Atrophy , Cryotherapy , Follow-Up Studies , Incontinentia Pigmenti , Light Coagulation , Retina , Retinal Detachment , Retinal Pigment Epithelium , Retinal Vessels , Retinaldehyde , Retinopathy of Prematurity , Traction
4.
Journal of the Korean Ophthalmological Society ; : 397-401, 1989.
Article in Korean | WPRIM | ID: wpr-145073

ABSTRACT

Sixteen eyes of 8 premature infants with stage 3 retinopathy of prematurity were treated with cryotherapy. Transconjunctival or transscleral cryotherapy was applied to the avascular retina with a cataract cryoprobe under general anesthesia. The mean follow up period was 8.2 months with a range of 4.5 to 14 months. Twelve(75%) of 16 treated eyes showed complete resolution of retinopathy of prematurity, while 4(25%) of 16 treated eyes showed cicticial change: 1 eye became cicatricial Grade I and 3 eyes Grade II.


Subject(s)
Humans , Infant, Newborn , Anesthesia, General , Cataract , Cryotherapy , Follow-Up Studies , Infant, Premature , Retina , Retinopathy of Prematurity
5.
Journal of the Korean Ophthalmological Society ; : 397-401, 1989.
Article in Korean | WPRIM | ID: wpr-145060

ABSTRACT

Sixteen eyes of 8 premature infants with stage 3 retinopathy of prematurity were treated with cryotherapy. Transconjunctival or transscleral cryotherapy was applied to the avascular retina with a cataract cryoprobe under general anesthesia. The mean follow up period was 8.2 months with a range of 4.5 to 14 months. Twelve(75%) of 16 treated eyes showed complete resolution of retinopathy of prematurity, while 4(25%) of 16 treated eyes showed cicticial change: 1 eye became cicatricial Grade I and 3 eyes Grade II.


Subject(s)
Humans , Infant, Newborn , Anesthesia, General , Cataract , Cryotherapy , Follow-Up Studies , Infant, Premature , Retina , Retinopathy of Prematurity
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