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Buccal tablets
Diclofenac sodium
Drug release
Mucoadhesion
Mucoadhesive tablets
Release kinetics
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Background: Evidence-based health policies are widely acknowledged as being essential for attaining ongoing improvements in health outcomes. This study represents a theoretical model to test and identify to identify the key drivers for adopting evidence-based healthcare practice (EBHP). Objectives: The goal of this study was to investigate the critical success factors for the adoption of evidence-based healthcare at a South African public hospital. Methods: Medical healthcare professionals were surveyed using a questionnaire developed by the researcher. The results were analysed with SPSS 23 and AMOS. A hypothetical model based on updated (D&M) IS Success Model, Technology, Organization and Environment framework (TOE) as well as Technology Acceptance Model (TAM) was developed and analysed using structural equation modelling (SEM). Results: The findings of this study indicate that EHR is crucial and the main construct influencing the adoption of EBHP. The findings of this study indicated a positive relationship between the construct electronic health records (EHR) with medical error reduction (MER), information quality (IQ) and knowledge quality (KQ), all showed a strong positive correlation towards the adoption of EBHP. Conclusions: Better coordination of patient care (BCP) typically results in lower health care costs. The results also show that using EBHP improves the accuracy of disease diagnosis and treatment, which lowers the burden of disease. Contribution: The developed framework will help healthcare systems that are strapped for money, particularly in developing countries.
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Delivery of Health CareABSTRACT
Objetivo: verificar o estado da arte da legística, notadamente a sua aplicação em matéria de saúde. Metodologia: foi utilizada a revisão de escopo para o levantamento, elegendo-se três repositórios de artigos científicos Biblioteca Virtual em Saúde; Portal de Periódicos da CAPES e Google Acadêmico. Utilizou-se como palavra-chave o termo legística. Foram considerados apenas os artigos redigidos em português e publicados entre 2017e 2021. Resultados: verificou-se que não é abundante a produção intelectual em língua portuguesa sobre o tema; foram identificados estudos aplicados apenas em Portugal, e os artigos de autores brasileiros restringiam-se à revisão doutrinária e publicação em periódicos jurídicos. Não se vislumbrou estudos sobre legística em que a saúde pública estivesse contemplada. Conclusão: concluiu-se que há uma lacuna do conhecimento em Saúde Coletiva, em que a legística pode ser instrumento para análise e avaliação de políticas públicas de saúde, tanto antes como após sua edição em norma jurídica.
Objective: to provide the current state of better regulation (legísticain Portuguese), particularly its application to health issues. Methods:a scoping review method was used. Three databases were selected Virtual Health Library; CAPES Journal Portal; and Google Scholar to provide an overview of scholarly articles. The term legísticawas used as keyword. Only articles written in Portuguese and published between 2017 and 2021 were considered.Results:it was found that the intellectual production in Portuguese on this topic is not very numerous. Applied studies were identified only in Portugal and articles by Brazilian authors were limited to doctrinal review and publication in legal journals. There were nostudies on better regulation related to public health. Conclusion:it was found that there is a knowledge gap in the field of public health, where better regulationcan be a tool for the analysis and evaluation of public health policies, both before and after their publication in a legal norm.
Objetivo: verificar el estado del arte de la jurisprudencia (legística en portugués), en particular su aplicación en lasalud. Metodología: se utilizó una revisión de alcance para la encuesta, eligiendo tres repositorios de artículos científicos Biblioteca Virtual en Salud; Portal Revista CAPES y Google Scholar. El término legística se utilizó como palabra clave. Se consideraron solo artículos escritos en portugués y publicados entre 2017 y 2021. Resultados: se constató que la producción intelectual en portugués sobre el tema no es abundante; los estudios aplicados se identificaron solo en Portugal, y los artículos de autores brasileños se restringieron a la revisión doctrinal y la publicación en revistas jurídicas. No hubo estudios de legisprudenciaen los que se contemplara la salud pública. Conclusión: se concluyó que existe un vacío de conocimiento en Salud Colectiva, en el cual la legisprudencia puede ser un instrumento para el análisis y evaluación de las políticas públicas de salud, tanto antes como después de su publicación en una norma jurídica.
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ObjectiveTo understand the influencing factors of women’s intention to utilize preconception health care services， so as to promote the utilization of preconception care among women with future pregnancy plan. MethodsThe study was conducted at 8 outpatient health clinics of medical institutions providing perinatal health care in Jiading District of Shanghai. Women who had fertility intention for another child were invited to complete an electronic questionnaire from November 2020 to February 2021. ResultsWomen with better pregnancy and birth care behaviors during the last periconception were more likely to utilize preconception care service before the next conception than those with previous poorer behaviors （OR=1.980， 95%CI= 1.061‒3.694， P=0.032）. Women with higher preconception care knowledge scores had better pregnancy and birth care behaviors during the last periconception than those with lower knowledge scores （OR=1.362， 95%C1= 1.004‒1.846， P=0.047）. ConclusionsIn order to improve the utilization of preconception care among the population with future pregnancy plan， it is necessary to further strengthen health education and social mobilization to promote the preconception eugenic knowledge， planned pregnancy and pregnancy and birth care behaviors.
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Background: The intra-operative blood loss which required transfusion is one of the complications in Ward-Mayo’s operation. The objective of this study was to evaluate its effectiveness to minimizes hemorrhage in Ward-Mayo’s operationMethods: It is a well-designed, Clinical, interventional, prospective, randomized control trial. In the department of obstetrics and gynecology, IPGMER-SSKM (PG) H, Kolkata, West Bengal, India. More than one-year study. After ethics approval, the total number of sixty-six cases will be selected with randomization for Ward-Mayo operation and allocated into two groups operated as - Gr-A (n = 33 cases) - by infiltrating locally tranexaminic acid, Gr-B (n = 33-controls) - application local conventional haemostatics.Results: The outcome informs of primary and secondary assessed, analyzed, tabulated and statistically significant showed accordingly as per graph pad software. In Table 1 and 2. The results of individual group (Gr. A and Gr. B) in forms of pry and Sec. outcomes showed that there are better outcomes in all aspects with zero mortality Tranexamic group than controls.Conclusions: This study concluded that the Tranexamic Acid can safely and effectively used by local infiltration during Ward-Mayo’ operation. Like other department, this technique can be utilized in other vaginal procedure (ex-Episiotomy).
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@#PURPOSE: Scholarly works have reported about the nurses' salary and its impact on job satisfaction, nurse turnover, retention, work condition, and provision of nursing care. However, studies are either focused on the nurses in government hospitals or nurses working outside the country. Thus, the study aims to explore and describe the lived experience of nurses employed in private hospitals in Albay province, the Philippines, and explicate the need for better pay. DESIGN: The study used a qualitative design, specifically a descriptive phenomenology approach. METHODS: Purposive sampling and in-depth interviews were conducted among seventeen (17) nurse informants. The audio-recorded interviews were transcribed verbatim and analyzed following the seven-stage process as described by Colaizzi (1978) for data coding and identifying themes. The same process of analysis performed among the responses or data gathered through electronic communication platforms. FINDINGS: Four themes and nine sub-themes were identified. The first theme is 'Over but under,' which includes three sub-themes: (1) Over-worked, underpaid working conditions, (2) Finding an additional source of income as a result of low-wages, (3) More nurses are produced, but less are staying in the country, (4) Required by law in the country but not permitted by low salary. The second theme is 'Same but different,' which includes three sub-themes: (1) The Nursing profession is akin to others, yet uncompensated, (2) Work demands are comparable to government hospitals. The third theme is 'Caring but uncared-for,' which includes two sub-themes: (1) Psychologically upsetting, (2) Stimulates nurses transition. The fourth theme is 'Selfless foresight,' which include only one sub-theme (1) Increasing the salary attracts nurses to stay in the country. CONCLLUSION AND RECOMMENDATIONS: The study results showed that nurses in private hospitals need better remuneration as they experience poor work conditions. Also, it described a low salary that impacts the nurses' workload, their physical and mental health, their socio-economic being, their ability to avail professional development, the retention or turnover, and the provision of nursing care. The study findings suggest data triangulation of the study in some other private hospitals outside the region and explore strategies for increasing nurses' retention and satisfaction. Nonetheless, these efforts will robust the empirical data about the need for better pay among nurses in the private sector.
Subject(s)
Job Satisfaction , Personnel Turnover , Hospitals, Private , Salaries and Fringe BenefitsABSTRACT
OBJECTIVE@#The primordial principle in living kidney donation is leaving the better functioning kidney (BFK) with the donor. However, when laparoscopic donor nephrectomy (LDN) is utilized, certain conditions may warrant removing the BFK. These include lesser complex vasculature, renal calculi, or left-sidedness. Reported here are the long-term outcomes of removing the BFK among living donors.@*METHODS@#Chart review was done on all donor nephrectomy patients over a five-year period. Patients whose BFK were removed via LDN were identified. Clinical indications, patient demographics, perioperative and postoperative outcomes were summarized. Creatinine and eGFR at one-day, one-month and one-year follow-up were used to determine renal functional outcomes.@*RESULTS@#Between January 2011 to December 2015, 810 donor nephrectomies were performed: 366 (45.2%) and 444 (54.8%) had open donor nephrectomy and LDN, respectively. BFK was removed in 26 (5.8%) in the LDN and none in the open group. Mean age was 28.9+7.5 (18-49), with a male to female ratio of 4:1. The clinical indications were less complex vasculature in 18 (69%), left-sided BFK in 7 (27%) and renal calculi in 1 (3.8%). The mean operative time was 173 +25 (130–272) minutes, with a mean blood loss of 111 +96 (50-200)cc. The mean length of stay was 3.0+0.2 (2.8-4) days. Grade 1 complications were seen in 5 (19%) patients. There was no mortality. The eGFR after 1 year is 79.4+14.1 (54-91) cc/min.@*CONCLUSION@#Removing the BFK during LDN does not impact negatively on the safety and renal functional outcomes of living kidney donors.
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Background: Substantial improvement can be brought about in the hospital inventory and drug expenditure by inventory control techniques. These include ABC (always, better and control), VED (vital, essential and desirable) and ABC-VED matrix analysis. The objective of the study was to categorize the drugs based on cost and criticality and identify those which require stringent managerial control.Methods: ABC analysis according to drug expenditure, VED analysis according to criticality of the drugs, ABC-VED matrix analysis to classify drugs into category I, II and III was done for drug store of a tertiary care teaching hospital of North India for the period of April, 2018 to March, 2019.Results: The total number of the drug items used by the drug store was 315. The total drug expenditure was Rs. 9,61,29,859. By ABC analysis, it was found that 15.24%, 22.54% and 62.22% items belonged to A, B and C category respectively, accounting for 70%, 20% and 10% of Annual Drug Expenditure (ADE). VED analysis showed that 31.11%, 60.32% and 8.57% were V, E, and D category items respectively, accounting for 30.44%, 57.12% and 12.44% of ADE. By ABC-VED matrix analysis, 42.86%, 52.38% and 4.76% items were category I, II and III items respectively, accounting for 78.91%, 20.15% and 0.94% of ADE.Conclusions: The study depicted the items belonging to category I which requires top managerial control, also the items belonging to categories II and III which require control by middle and lower managerial level respectively.
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Background: An efficient inventory control system would help optimize the use of resources and eventually help improve patient care. Objectives: The study aimed to find out the surgical consumables using always, better, and control (ABC) and vital, essential, and desirable (VED) technique as well as calculating the lead time of specific category A and vital surgical consumables. Methods: This was a descriptive, record-based study conducted from January to March 2016 in the surgical stores of the All India Institute of Medical Sciences, New Delhi. The study comprised all the surgical consumables which were procured during the financial year 2014–2015. Stores ledger containing details of the consumption of the items, supply orders, and procurement files of the items were studied for performing ABC analysis and calculating the lead time. A list of surgical consumables was distributed to the doctors, nursing staff, technical staff, and hospital stores personnel to categorize them into VED categories after explaining them the basis for the classification. Results: ABC analysis revealed that 35 items (14%), 52 items (21%), and 171 items (69%) were categorized into A (70% annual consumption value [ACV]), B (20% ACV), and C (10% ACV) category, respectively. In the current study, vital items comprised the majority of the items, i.e., 73% of the total items and essential (E) category of items comprised 26% of all the items. The average internal, external, and total lead time was 17 days (range 3–30 days), 25 days (range 5–38) and 44 days (range 18–98 days), respectively. Conclusions: Hospitals stores need to implement inventory management techniques to reduce the number of stock-outs and internal lead time.
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Background: This have a look at evaluated the position oflaparoscopic surgical procedure is the early control of acutegallbladder disease among a hundred and twenty patients inShaheed Suhrawardy Medical College Hospital and PrivateClinics of Dhaka City.Methods: Information of all emergency admissions for acutegallbladder diseases from March 2014 to June 2016 wasidentified and additional data from the hospital facts becomereviewed retrospectively.Results: Hundred and twenty students are gallbladder disease(87 patients presented with acute biliary pain and 33 patientspresented with acute cholecystitis). The conversion rate turnedinto better throughout early laparoscopic surgical treatment foracute calculous cholecystitis than in operations for acute biliarycolic. In sufferers with acute calculous cholecystitis theconversion charge turned into extensively lower in operationswithin 48 hour of admission than when surgical procedurebecome not on time past 48 h or ultimately carried outelectively.Conclusion: Laparoscopic cholecystectomy for acutegallbladder diseases should be performed well and givepositive feedback after the surgery.
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Objective: To establish fingerprints of Euodiae Fructus in different years by UPLC, analyze them with chemical pattern recognition technology, and determine the content of four quality difference markers, so as to provide new ideas for the research of Euodiae Fructus “Chen Jiuzhiliang” and provide basis for its quality evaluation. Methods: The fingerprints of Euodiae Fructus samples in three different years were established based on UPLC method. The similarity was calculated by the Similarity Evaluation System of Chromatographic Fingerprints of Traditional Chinese Medicine (2012A edition), and the pattern recognition was carried out by principal component analysis (PCA) and orthogonal partial least squares-discriminant analysis (OPLS-DA). Results: UPLC fingerprints of 47 batches of Euodiae Fructus samples (similarity > 0.997) were established, 40 common peaks were identified and 12 of them were identified. PCA and OPLS-DA analysis were used to effectively distinguish three different years of Euodiae Fructus. A total of 22 quality differential markers were screened, and the content of neochlorogenic acid, chlorogenic acid, evodiamine and rutaecarpine were determined. Conclusion: The combination of UPLC fingerprint of Euodiae Fructus and multi-component chemical pattern recognition technology can effectively distinguish Euodiae Fructus in different years and provide reference for “the older, the better” and quality control of Euodiae Fructus.
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Follow-on drug approach is to follow-up and make-up of the innovation of pioneering drugs. Since the millennium new molecular entities (NME) have experienced ample optimization, and the patents have claimed in wide ranges, as well as the drug administration requires NME being superior or non-inferior to the existing drugs of the same class. These situations have made the space of follow-on drug innovation narrow and smaller than before. The follow-on drug approach can be concisely differentiated into two aspects:one is to start from the chemistry of small molecules, which are performed with a niche-targeting manipulation to optimize the safety, efficacy and (or) convenience for dose superior to the existing drugs; another proceeds with the macromolecule targets. Based on the knowledge of the mechanism of action or of target mutation, active compounds are constructed through complementary binding or by the reaction mechanism. In this article successful examples are briefly described to illustrate the features of follow-on drug approach.
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A pesar de la importancia del ecosistema de páramo en el ciclo global de carbono no se dispone de una síntesis que permita diferenciar si es la biomasa vegetal o el suelo el componente que acumula la mayor cantidad de carbono. En este documento se busca integrar los aspectos fundamentales relacionados con el carbono almacenado en el ecosistema de páramo, a través de: 1) Revisar las estimaciones de carbono en biomasa aérea y suelo reportadas por la literatura para el ecosistema de páramo; 2) Examinar los efectos producidos por la actividad agropecuaria en el carbono almacenado en el páramo y 3) Identificar prácticas que reducen las emisiones de carbono en el páramo. Se revisaron artículos en bases de datos como Science Direct Springerlink, Willey Online Library y Google Scholar El componente que almacena mayor cantidad de carbono en páramo es el suelo, con contenidos entre 119 y 397 t/ha en los primeros 40 cm de profundidad. Mientras que la biomasa aérea varía entre 13,21 y 183 t/ha. Es necesario incrementar las investigaciones sobre carbono orgánico en suelos de páramo. Esta información podría contribuir a apoyar acciones tendientes a vincular los ecosistemas de paramo al mercado de carbono.
Despite the importance of the paramo ecosystem in the global carbon cycle, there is not an available synthesis for identifying if plant bio-mass or soil accumulates the maximum amount of carbon. The purpose of this document is to focus on paramo ecosystem stock carbon, throught: 1) to review estimates for the abovegroundbiomass and soil organic carbón; 2) to examine the agricultural production effects on carbon storage, and 3) to identify management practices for reducing carbon emissions in the paramo ecosystem. We searched papers about carbon storage in paramo in databases like Science Direct, Springerlink, Willey Online Library y Google Scholar. Soil stored more carbon than aboveground biomass. Soil carbon organic (SOC) between 119 and 397 t/ha was storaged in the upper 40 cm. Meanwhile, aboveground biomass carbon varied between 13,21 y 183 t/ha. More studies about SOC are requiered. This information could contribute to support actions over the entailment of paramo ecosystem in carbon markets.
Apesar da importância do ecossistema de páramo no ciclo global do carbono não está disponível uma síntese para diferenciar se é a biomassa vegetal ou solo, o componente que acumula a maior parte do carbono. Este trabalho procura integrar os aspectos fundamentais do carbono armazenado no ecossistema páramo, por meio de: 1) Rever as estimativas de carbono na biomassa e no solo relatado pela literatura para o ecossistema páramo; 2) Analisar os efeitos da atividade agrícola no carbono armazenado no páramo e 3) Identificar práticas que reduzem as emissões de carbono no páramo. Artigos foram revistos em bases de dados, tais como Science Direct SpringerLink Wiley Online Library e Google Scholar. O componente que armazena a maior parte do carbono é o solo, com contidos entre 119 e 397 t/ha nos primeiros 40 cm de profundidade. Enquanto a biomassa varia entre 13,21 e 183 t / ha. É preciso acrescentar a pesquisa sobre carbono orgânico no solo em páramo. Esta informação poderia ajudar a apoiar as ações para vincular os ecossistemas de Páramo ao mercado de carbono.
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Background: The basic principle of inventory control is Always Better Control (ABC) based on cost criteria and Vital Essential Desirable (VED) on criticality. Inequity in drug prioritization and expenses directly affects the health of the community. Study design: Based on ABC-VED matrix, inventory analysis was done. Study area: Community health centre (CHC) - Singarva, two primary health centres (PHC) - Kanbha and Sanathal and two urban health centre (UHC) - Amraiwadi and Sabarmati. Study period: December 2012 to December 2013. Methods: The drugs were first categorized by ABC method and then by VED method. On coupling the two techniques, ABC-VED matrix was made and drugs were classified in to Category I (AV + BV +CV + AE + AD), Category II (BE + CE + BD) and Category III (CD). Results: According to VED analysis large amount of money was spent on D category that is; 35% of annual drug expenditure (ADE) from CHC, 7.6% and 23.4% from both the PHC respectively, 20.1% and 24.7% from both the UHCs. On considering the ABC-VED matrix analysis the ADE spent on Class III was 6.6% among CHC, 1.2% and 1.5% among PHC, 2.6% and 7.2% among the UHC. Conclusion: The ADE used among the ABC-VED Class III should be avoided and the ADE on Class II drugs should be controlled and used judiciously.
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The present study revealed that all characters showed in variable crosses depicted heterosis in both positive and negative directions indicating that genes with negative as well as positive effects were dominant. The cross JCS-596 x Swetha showed highest positive heterosis for number of branches per plant over mid parent. The range of heterosis for number of capsules per plant was 74.27 to 50.74 over better parent. Maximum positive heterosis for number of capsules per plant was exhibited by NIC 8283x KMR-74 over mid parent and better parent. The magnitude of heterosis was 103.62 % and 98.53 % over mid parent and better parent for yield per plant respectively. The hybrids Rajeswari x Swetha, Chandana x Swetha, JCS-596 x KMR-74, JCS-596 x Swetha and NIC 8283x KMR-74 recorded highly significant positive standard heterosis for plant height. Maximum significant standard heterosis for number of capsules per plant was found in the crosses NIC 8283 x KMR-74, Chandana x Swetha and NIC-8392 x Swetha. The crosses Chandana x Swetha (36.63%) and NIC 8283 x KMR-74 (18.26%) were exhibited highest standard heterosis for seed yield per plant.The crosses JCS-596 x Swetha, NIC 8283 x KMR-74 and Chandana x Swetha can be utilized in heterosis breeding.
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Este artigo apresenta a Atenção Humanizada ao Recém-Nascido de Baixo-Peso - Método Canguru - como uma diretriz clínica na assistência neonatal, e busca traçar um paralelo com outro importante componente do cuidado infantil descrito na literatura internacional: o cuidado centrado na família. O artigo propõe que a Atenção Humanizada ao Recém-Nascido de Baixo-Peso - Método Canguru seja vista como uma boa prática e seja considerada também no campo das tecnologias em saúde.
The main purpose of this paper is to introduce the Human Attention of Low Birth Weight-Kangaroo Care as clinical guidelines in neonatal intensive care. It will also try to link this clinical guideline and another component of neonatal infant care: the Family-Centered Care. Based on this relationship, this paper proposes that Human Attention of Low Birth Weight-Kangaroo Care should be catalogued as a Potentially Better Practices and also, considered as a Health Care Technology.
Subject(s)
Infant, Newborn , Perinatal Care , Biomedical Technology , Infant, Low Birth Weight , Maternal-Child Health Services , Practice Guidelines as Topic , Professional-Family Relations , Brazil , Humanization of Assistance , Quality of Health CareABSTRACT
The efficiency of simulated annealing algorithms and rapid chain delineation in establishing the best linkage order, when constructing genetic maps, was evaluated. Linkage refers to the phenomenon by which two or more genes, or even more molecular markers, can be present in the same chromosome or linkage group. In order to evaluate the capacity of algorithms, four F2 co-dominant populations, 50, 100, 200 and 1000 in size, were simulated. For each population, a genome with four linkage groups (100 cM) was generated. The linkage groups possessed 51, 21, 11 and 6 marks, respectively, and a corresponding distance of 2, 5, 10 and 20 cM between adjacent marks, thereby causing various degrees of saturation. For very saturated groups, with an adjacent distance between marks of 2 cM and in greater number, i.e., 51, the method based upon stochastic simulation by simulated annealing presented orders with distances equivalent to or lower than rapid chain delineation. Otherwise, the two methods were commensurate through presenting the same SARF distance.
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En América Latina, incluyendo Cuba, se observa un incremento cuantitativo de los procesos de evaluación y la calidad se ha convertido en tema de preocupación por parte de las instituciones. La experiencia mundial combina mecanismos de autoevaluación y de evaluación externa, en la casi totalidad de sistemas de acreditación, aunque se reconoce que la autoevaluación es una de las formas más adecuadas para asegurar el avance constante hacia una mayor calidad. Pretendimos como objetivos de este trabajo: proponer las principales etapas por las que debe transitar la autoevaluación, así como argumentar la estructura que debe tener el informe de autoevaluación. A partir de la bibliografía consultada y de nuestra propia experiencia, hicimos la propuesta de cinco etapas en el proceso de autoevaluación:1) fase preparatoria, 2) recopilación de información a partir de indicadores seleccionados previamente, 3) interpretación y valoración de la información obtenida, 4) elaboración del plan mejora derivado de las fortalezas y debilidades identificadas previamente,5) fase de monitoreo y seguimiento de la implementación del plan de acción. En relación con la estructura del informe de la autoevaluación se propone la siguiente: Presentación, Introducción, Características del proceso de la autoevaluación, Síntesis evaluativa, Anexos, Plan de Mejoras.
A quantitative increase in the evaluation process is observed in Latin America including Cuba. Quality has become an important topic in different institutions. In the system of accreditation, world experience combines self- evaluation mechanism and external evaluation; although it is recognized that self-evaluation is one of the most adequate form to ensure the constant advance to a higher quality. The objective of this work is to suggest the principal phases of self-evaluation, and at the same time to justify the structure that the self-evaluation report should have. Taking into consideration the bibliographic review and our own experience, five steps in the evaluation process were proposed: 1) preparatory phase, 2) collecting information according to the previous indicator selected, 3) analysis and assessment of the information obtained, 4) elaboration of the plan as a result of the strengthens and weakness previously identified, 5) monitored and followed phase of the action plan implementation. In relation to the structure of the self-evaluation report, the following aspects are suggested: Presentation, Introduction, Characteristics of the self-evaluation process, Evaluative Synthesis, Appendices, Plan to be better.
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BACKGROUND AND OBJECTIVES: Sensorineural hearing loss is one of serious complications caused after the operation of chronic ear disease. In only/better hearing ears, it is important to minimize the chances of developing a severe hearing loss and to stop the progression of disease. We report the results of performing epitympanoplasty with mastoid obliteration in the only/better hearing ear with cholesteatoma. SUBJECTS AND METHOD: From February 11, 1996 to April 16, 2003, epitympanoplasty and mastoid obliteration was performed for 6 patients with the only hearing ear and 2 with a better hearing ear. In the only/better hearing ears, 7 cases had cholesteatoma and 1 case had adhesive otitis media. The other ears of the 5 cases had previously received canal wall down mastoidectomy, 2 cases sensorineural hearing loss and 1 case both epitympanoplasty and mastoid obliteration. The observation period ranged from 7 to 99 months, with the average of 45 months. RESULTS: One-staged operation was performed on all 8 patients. Four cases got total ossicular replacement prosthesis, 3 cases received partial ossicular replacement prosthesis, and 1 case received autologous cartilage short columellization. After each operation, all patients obtained a dry, safe, self-cleansing ear and recurrence did not occur. The hearing results in this series showed that the air conduction thresholds, bone conduction thresholds and air-bone gaps were preserved in 7 cases, but became worse in one patient. Two patients did not need to use hearing aids, five patients used an hearing aid of in-the-canal (ITC) type, one patient used a hearing aid of completely-in the canal (CIC) type. CONCLUSION: Epitympanoplasty with mastoid obliteration in the only/better hearing not only can stop the progression of cholesteatoma, but also can preserve hearing of patients.