ABSTRACT
Resumo Uma das principais modificações ocorridas no organismo em decorrência do treinamento físico-esportivo envolvendo exercícios físicos de longa duração é o aumento na quantidade e qualidade funcional de mitocôndrias do tecido muscular esquelético. Não existe até o momento um mecanismo causal explicativo para esse fenômeno. A proposta a ser discutida neste ensaio é denominada por "hipótese do acoplamento elétrico-transcripcional". Segundo a mesma, modificações na atividade elétrica celular, principalmente de despolarização membranar, constituem-se em método de controle e regulação dos processos de biossíntese no organismo multicelular. Por exemplo, estudos que provocaram hiperpolarização artificial em células somáticas induziram diferenciação celular e supressão da proliferação, sendo que o contrário ocorreu com a despolarização. Ou seja, a despolarização celular durante o exercício físico devido a contração muscular intensa e constante pode ativar processos responsáveis por biossínteses e, possivelmente, duplicação de mitocôndria.
Abstract One of the main changes happened in skeletal muscle tissue as a result of physical and sport training with prolonged exercise is the increase in the quantity and functional quality of mitochondria. There is not yet an explanatory causal mechanism for this phenomenon. The suggestion to be discussed in this assay is called "electric-transcriptional coupling hypothesis". In this hypothesis, changes in electrical activity, mainly membrane depolarization, are considered methods used for the control of biosynthesis in multicellular organisms. For example, studies that resulted in somatic cell hyperpolarization induced suppression of differentiation and proliferation, and the opposite happened with depolarization. That is, cell depolarization that occur during the exercise as a consequence of intense and prolonged muscle contraction could activate processes responsible for biosynthesis and, possibly, mitochondrial replication.
Subject(s)
Humans , Exercise/physiology , Oxidative Stress/physiology , Energy Metabolism/physiology , Metabolism/physiologyABSTRACT
Objective Observe the effect of of U8 similar bioelectricity stimulant therapy of infertility with gracile endometrium on endometrium reception .Methods 80 cases of patients in 252 natrual period with infertility caused by poor endometrial develop-ment for unknown reasons were randomly divided into two groups .The treatment group was intervened by U8 similar bioelectricity stimulant other day from the eighth day of menstruation until the day to inject HCG .After ovulation ,patients were sustained by progestin with a dose of 20 mg per day .The control group was given estradiol valerate with a dose of 2mg per day from the eighth day of menstruation until the day to inject HCG .After ovulation ,patients were sustained by progestin with a dose of 20mg per day as well .To compare the generral conditions on HCG injection day of the two groups anterior-posterior :both groupsal thickness and types ,parameters of intramembrane and submucosal uterine blood flow ,biochemical pregnancy rates and clinical pregnancy rates . Results The endometrial thickness and types on HCG injection day in treatment group were improved significantly (P<0 .05) . The parameters of intramembrane and submucosal uterine blood flow were better than the control ,there was a significant difference ( P<0 .05) .And the clinical pregnancy rate of treatment group was higher than that of control group there was a significant differ-ence(P<0 .05) .Conclusion U8 similar bioelectricity stimulation can promote the grow th of endometrium ,improve the endometrial receptivity and the clinical pregnancy rate .
ABSTRACT
Microbial fuel cells (MFCs) convert biomass into electricity by the metabolic activity of microorganisms and are also used for remediation and water treatment. Power output was compared for a dual chambered membrane MFC using either E. coli or two Yamuna river samples, Yamuna (before the Sangam region)—slow flow (sample 1) and Sangam region —fast flow (sample 2). E. coli and the two river water samples 1 and 2 gave a maximum voltage of 779, 463 and 415 mV respectively. Using E. coli the maximum power density obtained with a 100 Ω resistor was 220.66 mW/cm2 and the highest power generated 6068.41 mW. The results demonstrate E. coli, river sample 1 and river sample 2 have a comparable coulombic efficiency of 85.2, 71 and 77% respectively when using 0.4% sucrose as substrate. The decrease in chemical oxidative demand of all river water samples using MFC technology demonstrates efficient remediation of inland water.
ABSTRACT
Con las investigaciones de Emil Du Bois-Reymond, uno de los fundadores de la electrofisiología, se dio inicio a la era de la bioelectricidad. DuBois documentó en detalle actividades eléctricas asociadas con excitación nerviosa, contracción muscular y procesos de cicatrización. En la actualidad es reconocido que los campos eléctricos (CE) están presentes en los organismos vivos y que direccionan e influyen procesos biológicos como la embriogénesis, regeneración y cicatrización de heridas. Diversos estudios han demostrado como los CE interfieren en la biosíntesis y la migración celular, dando lugar a nuevas estrategias para la reparación de ligamentos y regeneración de tejidos. En la actualidad las corrientes y CE biológicos suministran información necesaria para diversos tipos de diagnósticos y tratamientos. En este trabajo se hace una revisión de algunos estudios realizados alrededor de la generación de campos bioeléctricos endógenos, sus sustratos biológicos y aplicaciones médicas.
The era of bioelectricity began with the investigations of Emil Du Bois-Reymond, one of the founders of electrophysiology. DuBois documented in detail electrical activities associated with nerve excitation, muscle contraction and healing processes. It is currently recognized that electric fields (EFs) are present in living organisms and that they direct and influence biological processes such as embryogenesis, regeneration and wound healing. Several studies have shown how EFs interfere with biosynthesis and cell migration, leading to new strategies for repairing ligaments and for tissue regeneration. At present, biological EFs and currents provide information needed for different types of diagnoses and treatments. This paper reviews some studies focused on the generation of endogenous bioelectric fields, their biological substrates and medical applications.
ABSTRACT
Acupuncture, which is a preventive and treating method without drugs of traditional medicine, has had a long-standing history. Classical acupuncture is still the main, irreplaceable treatment method (electricity acupuncture in nature is classical acupuncture which is added by electricity into acupunctured spots). When giving the needle in patients, they will react against and have pain feeling, level of pain depends on different areas of the body, whenever receptors in skin and muscle will identify and make nervous pulses that will go to central nervous system through nerves. The second electric potential appears when acupuncturing needle into the body, that is injury electric potential. The third electric potential appears when the acupuncture needle is made of metal
Subject(s)
Acupuncture , ElectroacupunctureABSTRACT
With the development of economy and coming of information eva,the whole living space has been filled with electromagnetic wave with various frequencies.The chance of exposure to electromagnetic field for people grows with each pass-ing day.Environmental pollution by electromagnetic radiation has become the forth public muisance after the occurance of at-mospheric pollution,water pollution and noise pollution,and has brough t about the potential hazardous effects on the health of residents and individuals occupationally exposed to electromagnetic field.The effects of electromagnetic radiation on peoples health and living are versatile.The present paper mainly summarized the effects of electromagnetic radiation on neurobehaviour,electrocardiogram and oncephalogram in order to more understand the hazard of electromagnetic radiation.
ABSTRACT
Aim To study the effect of total flavones of Rhododendra(TFR)on bioelectricity changes of ventricular myocytes in guinea pigs. Methods Conventional microelectrode technique was used to record action potentials (AP) , resting potentials (RP) and effective refractory period (ERP). Results TFR 25,50 mg?L-1 decreased the action potential duration at 50%,90% repolarization (APD50,APD90) while TFR 100,200,400 mg?L-1 prolonged APD50 and APD90Significantlg. TFR 200,400 mg?L-1markedly decreased action potentials amplitude (APA) and velocity maximum of depolarization (Vmax). TFR 400 mg?L-1decreased resting potential. TFR 200 mg?L-1 prolonged ERP. Conclusion TFR may antagonize Ca2+ inward flow at lower concentration and block K+ inward flow at higher concentration.