Mammary botryomycosis: two concomitant cases in mares: case report / Botriomicose mamária: dois casos concomitantes em éguas: relato de caso

Mammary disorders in mares are rare and usually only one animal per paddock is affected. In this report, two mares with 7 and 9 years old, were concomitantly diagnosis of chronic pyogranulomatous mastitis, associated with the Splendore-Hoeppli reaction, indicative of botryomycosis a rare, chronic suppurative disease with microabscess formation, characterized by in vivo formation of eosinophilic materials around microorganisms or biologically inert material. Various bacteria can cause botryomycosis in horses, and the most frequently isolated one is Staphylococcussp., particularly S. aureus. This report confirms the role of Staphylococcus sp.; however, specifically S. hyicus and S. cohnii that prior to the current report, had not been associated with cases of botryomycosis.(AU)

Enfermidades mamárias em éguas são raras e, normalmente, apenas um animal é afetado. Neste relato, duas éguas, de sete e nove anos, foram diagnosticadas concomitantemente com mastite crônica piogranulomatosa, associada com reação de Splendore - Hoeppli, indicativa de botriomicose, uma doença crônica supurativa rara, com formação de microabscessos caracterizados pela presença de material eosinofílico em torno dos microrganismos ou de material biologicamente inerte. Várias bactérias podem causar botriomicose em cavalos, sendo Staphylococcus sp., particularmente S. aureus, as mais frequentemente isoladas. Este relato confirma o papel do Staphylococcus sp, no entanto este é o primeiro relato em que S. hyicus e S. cohnii foram identificados em lesões relacionadas à botriomicose.(AU)

Facial botryomycosis-like pyoderma in an HIV-infected patient: remission after initiation of darunavir and raltegravir

Abstract Botryomycosis is an uncommon, chronic, suppurative, bacterial infection that primarily affects the skin and subcutaneous tissues. It has long been associated with defects of cellular immunity. We report a 28-year-old woman who presented with a chronic, ulcerated lesion with draining sinuses in the right malar region. Predisposing factors were HIV infection with poor immunological control, alcoholism, and a previous trauma to the right cheek. Several courses of antimicrobial therapy provided only partial and temporary remission. Complete clinical remission was only achieved 5 years later when a novel antiretroviral regimen composed of darunavir and raltegravir was initiated.

A Case of Splenic Botryomycosis Caused by Streptococcus mitis in a Patient with a Previous Distal Gastrectomy / 대한내과학회지

Botryomycosis is an uncommon chronic suppurative bacterial infection of the skin and visceral organs seen primarily in immunocompromised patients. Here, we report a case of splenic botryomycosis caused by Streptococcus mitis in a 53-year-old immunocompetent woman with a history of distal gastrectomy for advanced gastric cancer.

Botryomycosis mimicking acute abdomen: a case report / Botriomicose simulando um abdome agudo: relato de caso

Botryomycosis is a rare chronic granulomatous bacterial infection affecting mostly the skin and subcutaneous tissues. The nomenclature is a misnomer as the disease is caused by bacteria, not by fungus. This uncommon infection sometimes mimics neoplasia and actinomycosis. Staphylococcus aureus is the most common agent in botryomycosis, followed by Pseudomonas sp. strains. We report an unusual case of invasive umbilical botriomycosis mimicking an acute abdomen. The patient recovered fully after being treated with surgery and antibiotics. This is the first report of umbilical Botryomycosis, which usually affects the skin.

Botriomicose é uma infecção bacteriana granulomatosa crônica rara que afeta principalmente a pele e tecidos subcutâneos. A nomenclatura é imprópria, uma vez que a infecção é causada por bactérias e não por fungos. Esta infecção incomum simula por vezes uma neoplasia ou actinomicose. O Staphylococcus aureus é o agente mais comum na botriomicose, seguido por cepas de Pseudomonas sp. Relatamosum caso incomum de botriomicose umbilical invasiva simulando um abdome agudo. A paciente recuperou-se totalmente após ser tratada com cirurgia e t antibióticos. Essa doença é mais frequente na pele, e este é o primeiro relato deBotriomicose umbilical.

A Case of Botryomycosis Caused by Staphylococcus lugdunensis in a Chronic Alcoholic / 대한피부과학회지

Botryomycosis is a chronic bacterial granulomatous and suppurative disease, which may be similar to the fungal disease, clinically and histologically. It is commonly caused by Staphylococcus aureus, but Pseudomonas aeruginosa, Escherichia coli, and Proteus spp. have been rarely involved. The known predisposing factors are trauma, postoperative complication, diabetes mellitus, chronic alcoholic, and so on. We present the botryomycosis caused by Staphylococcus lugdunensis, which is a rare virulent pathogen of botryomycosis, in a chronic alcoholic.

A Case of Botryomycosis at the Excoriation Site in a Patient with Chronic Eczema / 대한피부과학회지

Botryomycosis is a chronic, granulomatous and suppurative infection. The skin is the most frequently affected organ. The most common species is Staphylococcus aureus, followed by Pseudomonas aeruginosa. Clinically, the skin lesions most commonly affect the hands and feet and they can appear as nodules, ulcers, sinuses, fistulae and verrucous plaques. Histopathologic examination reveals grains with surrounding eosinophilic material and inflammatory cells. We report here on a case of botryomycosis at the excoriation site in a 90-year-old female patient with chronic eczema.

Red grain botryomycosis due to Staphylococcus aureus - A novel case report.

Staphylococcus aureus and some other bacteria are known to cause botryomycosis. These bacteria are known to produce yellowish-white soft grains. Only Actinomadura pelletieri is known to produce red grains. We report here a case of an intensely inflammatory type of botryomycosis. A 35-year-old male labourer presented with swelling, redness and multiple sinuses on his foot, of eight months duration. The purulent discharge contained bright red coloured grains, 0.5 to 1 mm in size, which were round to oval in shape. Gram-positive cocci were demonstrated in crushed granules and tissue sections. Culture yielded pure and heavy growth of Staphylococcus aureus . He responded very well to cefazolin. There is no other report of such red grain botryomycosis due to Staphylococcus aureus , available in literature. This is first case report of its kind in world literature.

A case of primary pulmonary botryomycosis by Gemella morbilium / 대한내과학회지

Botryomycosis is a chronic supprative disease with characteristic granules formation in the pus caused by bacteria and frequently is mistaken for a fungal infection. Pulmonary botryomycosis can resemble actinomycosis, tuberculosis, or invasive carcinoma by causing a mass lesion with constitutional symptoms. We report a case of pulmonary botryomycosis in a 43 years old man. He had a cavitary lesion of the right upper lobe and diagnosis was confirmed by percutaneous needle aspiration. The specimen demonstrated multiple clusters of bacteria within abscess that best were visualized by gram staining. Cultures of the biopsy materials yielded pure growth of Gemella morbilium. The patient recovered quickly after antibiotics treatment for 3 weeks.

A Case of Botryomycosis Occurring at the Axilla of the Patient with Acute Myeloid Leukemia / 대한피부과학회지

Botryomycosis is a rare bacterial infection that may mimic fungal disease both clinically and histologically. Cutaneous botryomycosis usually appears as nodules, sinuses, fistulae, abscesses, and ulcers with seropustular secretion. Histopathological findings are characterized by chronic nonspecific inflammatory lesions composed of neutrophils, lymphocytes, eosinophils and plasma cells. The characteristic suppurative foci contained granuloma with a basophilic center and an eosinophilic periphery. Successful treatment often requires a combination of both surgical debridement and long-term antimicrobial therapy. The predisposing factor included skin trauma, postoperative complication, diabetus mellitus, liver disorder, long-term steroid therapy, alcholism, and cystic fib rosis. Here we report a patient who had suppurative nodule with induration at the axilla. Staphylococcus aureus was cultured from the lesion. Our patient responded to systemic antimicrobial therapy and surgical debridement.

A Case of Visceral Botryomycosis Accompanied by Early Lung Cancer / 대한내과학회지

Botryomycosis is a rare, chronic and suppurative di- sease that is often mistaken clinically and histologically for a fungal infection, because the histologic feature shows a cluster of bacteria found within an eosinophilic matrix or capsule, giving the appearance of granules mimicking the sulfur granules of actinomycosis. Staphy- lococcus aureus is the most common organism cultured from lesions of botryomycosis, but other bacteria have also been isolated and implicated, including Psudomonas aeruginosa, E. coli, Proteus spp., Bacillus spp.. In some case, multiple pathogenic bacteria were found on cul ture. This disease has two patterns of organ involve ment. The more common type is cutaneous type, which involves the skin, subcutaneous soft tissue, muscle and bone. The other is visceral type which involves the lungs, liver, tongue, orbit, bowel, brain, kidney or pros tate. We report a case of brain and pulmonary botry omycosis in a 60 year-old man, who have early lung cancer. Botryomycosis was diagnosed by brain mass removal, PCNA and bronchoscopy, and lung cancer was detected incidentally by bronchoscope. The patient was treated with the Penicillin G after operation of brain mass, and right pneumonectomy was done.

Cerebellar Botryomycosis: Case Report

A 60 year old male patient with a medical history of pulmonary tuberculosis presented with severe headaches and general weakness. Radiological studies revealed mass lesions both in the right using and the right cerebellar hemisphere. Clinically metastatic brain tumor and tuberculoma were highly suspected. The cerebella mass was totally excised and an unusual pathologic result was reported as botryomycosis. According to literatures reviewed, botryomycosis is a chronic bacterial infectious lesion resembling actinomycosis and mycotic abscess and it has been frequently reported in the skin, subcutaneous lesions and other visceral organs, but the cases of brain involvement were extremely rare. This article is a case report of a cerebellar botryomycosis. The pathologic characteristics and the differential diagnosis of botryomycosis are discussed.