ABSTRACT
Aims: Metastases of leukemia and lymphoma to both breasts were very rare. We have aimed to report a rare and interesting case that presented with metastases of leukemia and lymphoma to both breasts. Case Report: A thirty-year-old woman has applied to our department with a four month story of painless masses in both of breasts. We have performed tru-cut biopsies to both breasts after clinical examination. Histological and immuno-histochemical profile analysis have revealed bilateral acute B - cell lymphoblastic lymphoma and acute B - cell lymphoblastic leukemia metastases. A positive response was observed after treating the patient with adjuvant systemic chemotherapy and consolidated radiation therapy. On the sixth month follow-up, no evidence of disease recurrence was identified. Discussion: In patients presenting with bilateral breast masses, considering that other tumors may metastasize to the breast, the details of this rare case may aid clinicians treating similar patients, and highlight the importance of this situation. Conclusion: This finding emphasizes the need to accurately identify these tumors as metastases in order to avoid unnecessary procedures and treatments in these patients.
ABSTRACT
Primary lymphoma arising from the uterine cervix has been rarely encountered, and breast involvement is rare because of the relative paucity of lymphoid tissue in the breast. A 32-year-old woman with a primary malignant lymphoma of the uterine cervix and breast involvement is reported. The patient presented with post-coital vaginal bleeding, and punch biopsy of the cervix revealed the diffuse large B cell type of malignant lymphoma. PET-scan was done for staging, and abnormal FDP uptakes were detected in a uterine cervical mass and breast nodule. Ultrasonography-guided needle biopsy was done for the breast mass, and 2 biopsied nodules revealed fibroadenoma and diffuse large B cell lymphoma. The patient (Ann Arbor stage IV) was treated with 6 cycles of combination chemotherapy with CHOP plus rituximab. The patient went into complete remission. Thereafter, 4500cGy pelvic irradiation was done for adjuvant therapy.