ABSTRACT
Objective To evaluate the value of fiber bronchoscope brush liquid based cytology in diagnosis and classification diagnosis of lung cancer.Methods Eigh hundreds and seventeen cases of lung cancer were retrospectively analyzed.All cases con-ducted the fiber bronchoscopy brush liquid based cytology exmination and histopathological examination.Then their results were compared.Results Three hundreds and sixty-eight casesof lung cancer were diagnosed by fiber bronchoscopy brush liquid based cy-tology,invluding 177 cases of squamous cell carcinoma,84 cases of adenocarcinoma and 68 cases of small cell carcinoma,and 15 ca-ses were separately diagnosed as lung cancer.The sensitivity of was 44.01%,specifity rate was 94.40%,positive predictive value was 95.92%,negative predictive value was 36.04%,and the Kappa value was 0.250,there was statistically significant difference compared with the histopathological examination(P<0.01).Conclusion Fiber bronchoscopy brush liquid based cytology examina-tion is a high specificity method to diagnose lung cancer.