Circumferential ablation of pulmonary vein ostium combined with vagal denervation for the treatment of atrial fibrillation：a clinical study / 介入放射学杂志

Objective To evaluate the impact of vagal denervation (VD) that is derived from circumferential ablation of pulmonary vein ostium for paroxysmal atrial fibrillation (AF) on the therapeutic results. Methods A total of 50 patients with paroxysmal atrial fibrillation were enrolled in this study. Circumferential ablation of pulmonary vein ostium was carried out in all the patients. The end point of ablation was pulmonary vein electricity isolation. The patients in whom VD occurred during the performance of ablation were regarded as VD- positive group (n = 19), and the remaining patients were used as VD- negative group (n = 31). The recurrence rate of AF six months after the treatment was recorded, and the results were compared between the two groups. Results The end point of ablation was successfully achieved in all the fifty cases. Six months after the ablation, the therapeutic effect of VD- positive group was significantly better than that of VD- negative group (84.21% vs 64.51%, P ≤ 0.05). Conclusion The vagal denervation effect that is derived from circumferential ablation of pulmonary vein ostium in treating AF can significantly increase the success rate of radiofrequency ablation for AF.

Treatment of refractory frequent ventricular premature beat by radiofrequency catheter ablation / 中国基层医药

Objective To study the curative effect on refractory frequent ventricular premature beat(VPB) by radiofrequency catheter ablation.Methods The refractory frequent ventricular extrasystoles of 18 patients were treated by radiofrequency catheter ablation(RFCA).The way of ventricular excited sequence and pacemaker-mapping was used to map and locate the site of VPB origin.When the original site of eliciting premature beat,where the excitation point of VPB appeared 20ms earlier than QRS waves of surface EKG or QRS waves of ablation electrode pacing electrogram were completely coincident with QRS waves of VPB,was localized,the frequency current should be delivered in situ.Results 18 patients were all successful,the success rate was 100%.No intraoperative or postoperative complications happened.Conclusion RFCA is an effective and safe surgical approach for frequent ventricular ectopic beats.