ABSTRACT
The purpose of this study was to determine if salivary chromogranin a secretion in dogs exhibits a circadian rhythm. Saliva sampling was performed during three different sessions occurring in three nonconsecutive 24-h periods. Sixteen healthy adult beagle dogs (8 males and 8 females) were moved to a sampling room and housed individually in cages. Saliva samples were obtained every 4 h from 12:00 p.m. to 12:00 p.m. the following day. In the interest of habituation, saliva was obtained hourly from each dog 3 h before the experiment was started. Salivary chromogranin A concentrations were measured using an enzyme-linked immunosorbent assay. No circadian rhythm was detected for salivary chromogranin A secretion, and no differences in salivary chromogranin A concentrations measured every 4 h were demonstrated during the 24-h cycle in dogs.
Subject(s)
Animals , Chromogranin A/analysis , Circadian Rhythm , Dogs/physiology , Saliva/chemistryABSTRACT
[Objective] We studied the relationship between circadian blood pressure variations and oriental medical observations in the elderly. <BR>[Methods] Subjects in the present study were 39 elderly patients who were aged 65 or older. For measurement of circadian blood pressure variations, ambulatory blood pressure monitoring (ABPM) was used. Meiji Oriental Medical Score (MOS) and Qi, Blood, Body Fluids Score (developed by Terasawa et al.) were used to evaluate Oriental Medical Status of the subjects.<BR>[Results and Discussion] In the subjects who showed abnormality in circadian blood pressure variations, symptoms of Lung, Kidney and Qi deficiency were identified using MOS, blood deficiency and Qi stagnation were identified using Qi, Blood, Body Fluids Score. The number of the oriental medical symptoms were significantly greater in the subjects who showed abnormalities in circadian blood pressure variations compared with the other subjects. We concluded that oriental medical observations would be helpful to suggest existence of abnormalities in circadian blood pressure variations in elderly with hypertension
ABSTRACT
PURPOSE--To determinate the circadian daily and weekly variations in the incidence of sudden death due to Chagas' disease. METHODS--In 50 chronic chagasic individuals with sudden death due to Chagas' disease and in 473 individuals with natural, not sudden death, we analyzed both the day of the week and the time of the death. Statistical tests were applied to determine the significance of the difference between proportions and averages. RESULTS--For the chagasic group the values indicated a highly significant excess of lethality for the period between 12 and 6pm. The occurrence of the sudden death was the same in the different days of the week for both groups. CONCLUSION--The observed results suggest that the sudden death associated with Chagas' disease has a circadian pattern with a vespertine peak. Weekly variations in the sudden death of chronic chagasic individuals were not detected