Discrimination of quality markers of Shujin Huoxue Capsules based on five principles coupled with cobweb model / 中国中药杂志

The quality markers(Q-markers) of Shujin Huoxue Capsules were comprehensively discriminated based on the five principles of transfer and traceability, specificity, compatibility, effectiveness and measurability. The compounds that could be transferred from the original medicinal materials to the preparation were selected with the principle of transfer and traceability. The specific components in the prescription were screened by reviewing literature with the principle of specificity. According to the principle of compatibility, the attributes of compounds were evaluated by the sovereign, minister, assistant and guide combination rules of the original medicinal materials in the prescription. According to the principle of measurability, the measurable components were summarized by reference to the pharmacopoeia and literature combined with the content. The mechanism of Shujin Huoxue Capsules in the treatment of osteoporosis was studied through network pharmacology based on the principle of effectiveness, which was the evaluation index of effectiveness. The chemical components screened out above were regarded as candidate Q-markers, and the cobweb model was plotted to obtain the comprehensive score of Q-markers. Hydroxysafflor yellow A, trachelosid, eleutheroside B, α-cyperone, protocatechuic acid, protocatechualdehyde and 4-methoxy salicylaldehyde were discriminated as the Q-markers of Shujin Huoxue Capsules based on the five principles combined with cobweb model.

Analysis on Problems in Circulation of Traditional Chinese Medicinal Materials from the Perspective of Economics / 中国中医药信息杂志

Circulation of traditional Chinese medicinal materials, as the vital part of the TCM industrial chain, plays an important role in the connection of agriculture link and industry link of traditional Chinese medicinal materials, which has influence on the healthy development of the whole TCM industrial chain. Because circulation activities mainly include exchange and storage activities instead of manufacturing real products, they are much more difficult to be managed compared with producing activity. This would lead to problems in circulation of traditional Chinese medicinal materials, and impose negative effects on TCM industry. Based on scale economy theory, information asymmetry theory and cobweb model theory, this article analyzed the problems in circulation of traditional Chinese medicinal materials, discussed the deep reasons behind these problems, and proposed relevant suggestions for optimization.