Abordaje terapéutico del colapso transversal del maxilar superior con microimplantes (TAD´s) / Therapeutic approach of transverse maxillary collapse with microimplants (TAD's)

Introducción. La atresia o estrechez del maxilar superior es una patología de origen multifactorial que genera un colapso transversal, el mismo e implica la carencia de espacio necesario para la disposición correcta de las piezas dentales. Objetivo. El presente artículo está enmarcado en una revisión narrativa de la literatura, con el objetivo de describir el abordaje terapéutico del colapso transversal del maxilar superior con microimplantes (TAD´s), determinando los efectos esqueléticos y dentoalveolares en el maxilar superior, así como las ventajas y desventajas del tratamiento. Método. La búsqueda de artículos se realizó a través de mediante las plataformas de: Scielo, PubMed, Google Académico y Medline. Se seleccionaron 21 artículos cuyos textos completos fueron descargados para examinarlos a detalle y verificar que cumplieran con todos los criterios de inclusión, de los cuales se obtuvieron 16 artículos para elaborar esta revisión narrativa. Conclusiones. El abordaje terapéutico del colapso transversal se produce por medio de la expansión rápida del maxilar (ERM) o disyunción maxilar, en pacientes jóvenes en crecimiento; y en los pacientes adultos se suele emplear un tratamiento con técnica MARPE con microimplantes (TAD´s). El principal efecto esquelético es la apertura de la sutura maxilar que varía de 2 a 10 mm, muchos autores coinciden en que el manejo del colapso transversal del maxilar superior con microimplantes no genera efectos dentoalveolares negativos, al contrario, tiene ventajas biomecánicas debido al anclaje con el hueso, reduciendo el riesgo de movimiento dentales indeseados y permitiendo un control del crecimiento vertical.

Introduction. The atresia or narrowness of the upper jaw is a pathology of multifactorial origin that generates a transverse collapse, it implies the lack of space necessary for the correct arrangement of the dental pieces. Objective. This article is framed in a narrative review of the literature, with the aim of describing the therapeutic approach of transverse maxillary collapse with microimplants (TAD's), determining the skeletal and dentoalveolar effects in the maxilla, as well as the advantages and disadvantages of treatment. Method. The search for articles was carried out through the following platforms: Scielo, PubMed, Google Scholar and Medline. 21 articles whose full texts were downloaded were selected to examine them in detail and verify that they met all the inclusion criteria, of which 18 articles were obtained to prepare this narrative review. Conclusions. The therapeutic approach to transverse collapse occurs through rapid maxillary expansion (RME) or maxillary disjunction, in young growing patients; and in adult patients, treatment with the MARPE technique with microimplants (TAD's) is usually used. The main skeletal effect is the opening of the maxillary suture, which varies from 2 to 10 mm. Many authors agree that the management of the transverse collapse of the maxilla with microimplants does not generate negative dentoalveolar effects, on the contrary, it has biomechanical advantages due to the anchorage with the bone, reducing the risk of unwanted dental movement and allowing control of vertical growth.

Educación y conocimiento liberador / Education and liberating knowledge

Resumen Este ensayo inicia con un aforismo sobre la educación: «forjadora de las fuerzas liberadoras hacia el progreso de la condición humana¼, en su connotación espiritual, intelectual, moral y convivencial en armonía con el ecosistema planetario (progreso dignificante). Se realza la coincidencia de las mayores cotas históricas de educación profesional con la extrema degradación de la cultura occidental, reveladora del papel de la educación que favorece la pasividad ante el conocimiento y el orden imperante. Se contrastan los caracteres de la educación pasiva con los de la participativa basada en el desarrollo del pensamiento crítico. Se define el pensamiento crítico y se argumenta el tipo de ambiente educativo que lo estimula y encauza, en particular, el pensamiento complejo e integrador alusivo al sí mismo proyectado al quiénes somos y dónde estamos, ignorado por la ciencia reduccionista. Se especifican el conocimiento liberador y su finalidad: «entendernos como humanidad fraterna y encontrar nuestro lugar en armonía con el concierto infinitamente diverso del mundo viviente¼. Se sintetizan las revoluciones teóricas -hoy desestimadas-, simientes del conocimiento liberador que develaron al antropocentrismo y a los etnocentrismos como «prisiones del espíritu¼. Se concluye que el conocimiento liberador cumple el papel utópico de orientar y señalizar el caminar interminable hacia el progreso dignificante.

Abstract This essay begins with an aphorism on education: "forger of the liberating forces towards the progress of the human condition", in its spiritual, intellectual, moral and convivial connotation in harmony with the planetary ecosystem (dignifying progress). It highlights the coincidence of the highest historical levels of professional education with the extreme degradation of Western culture, which reveals the role of education that favors passivity in the face of knowledge and the prevailing order. The characteristics of passive education are contrasted with those of participatory education based on the development of critical thinking. Critical thinking is defined and the type of educational environment that stimulates and channels it is argued, in particular the complex and integrative thinking alluding to the self projected to who we are and where we are, absent in reductionist science. Liberating knowledge is specified and its purpose defined as "to understand ourselves as fraternal humanity and to find our place in harmony with the infinitely diverse concert of the living world". The theoretical revolutions -now dismissed- being seeds of liberating knowledge that revealed anthropocentrism and ethnocentrisms as "prisons of the spirit" are synthesized. It is concluded that liberating knowledge fulfills the utopian role of signaling the endless walking towards dignifying human progress.

Effect of fluorescence method on cardiopulmonary function, immune function and safety during pulmonary segmental resection / 中国医师进修杂志

Objective:To explore the effects of fluorescence method and improved expansion and collapse method on cardiopulmonary function, immune function and safety during segmental pneumonectomy.Methods:One hundred and fifty-six patients with lung segmental resection operation in Yucheng People′s Hospital from March 2018 to August 2020 were enrolled. They were divided into two groups according to the random number table method, each group with 78 patients. The patients in the observation group were treated with fluorescence method and the patients in the control group were treated with modified expansion collapse method. The operation indexes, immune function and cardiopulmonary function of the two groups were compared, and the incidence of postoperative complications were counted.Results:The intraoperative time and the appearance time of intersegmental plane in the observation group were shorter than those in the control group: (105.33 ± 10.62) min vs. (139.46 ± 12.58) min, (15.46 ± 1.13) s vs. (724.56 ± 65.65) s, there were statistical differences ( P<0.05). After operative for 1, 7 d, the levels of 6 min walking distance, peak expiratory flow rate, percentage of forced vital capacity and percentage forced expiratory volume in 1 second in the observation group were higher than those in the control group: after operative for 1 d: (475.36 ± 10.29) m vs. (412.11 ± 13.33) m, (284.52 ± 10.33) L/min vs. (251.13 ± 12.89) L/min, (85.65 ± 3.21)% vs. (81.13 ± 1.43)%, (83.25 ± 2.55)% vs. (74.49 ± 2.53)%; after operative for 7 d: (510.23 ± 16.66) m vs. (488.33 ± 15.42) m, (302.13 ± 15.58) L/min vs. (285.12 ± 10.22) L/min, (93.46 ± 5.79)% vs. (88.44 ± 5.44)%, (92.25 ± 2.32)% vs. (85.54 ± 2.13)%, there were statistical differences ( P<0.05). After operative for 1, 7 d, the levels of CD 4+/CD 8+, CD 8+, CD 4+ in the observation group were higher than those in the control group: after operative for 1 d: 0.85 ± 0.10 vs. 0.52 ± 0.04, 0.305 ± 0.025 vs. 0.285 ± 0.012, 0.325 ± 0.021 vs. 0.304 ± 0.025; after operative for 7 d: 1.13 ± 0.10 vs. 1.02 ± 0.07, 0.324 ± 0.029 vs. 0.306 ± 0.023, 0.359 ± 0.024 vs. 0.332 ± 0.025, there were statistical differences ( P<0.05). The rate of postoperative complications in the observation group was lower than that in the control group: 2.56%(2/78) vs. 11.54%(9/78), there was statistical difference ( χ2 = 4.79; P = 0.029). Conclusions:Both the fluorescence method and the modified inflation-collapse method have certain therapeutic effects, but the combination of fluorescence method in segmentectomy can provide reliable technical support and reduce the impact on cardiopulmonary function.

Progress of late-onset circulatory collapse in preterm infants / 国际儿科学杂志

Late-onset circulatory collapse(LCC)in preterm infants is characterized by sudden onset of hypotension and/or oliguria after the first week of life, which is resistant to volume expanders and inotropes but responds rapidly to timely glucocorticoids treatment.LCC should be managed promptly and properly, or it may cause respiratory, digestive complications and life-long neurological problems.Relative adrenal insufficiency is considered the most likely cause of LCC, but its pathophysiology remains unclear.This review summarizes the current reserch about LCC regarding its pathophysiology, clinical features, diagnosis, treatment, and prognosis.

Osteoclast-mediated pain and collapse mechanisms in the femoral head necrosis with bone marrow edema / 西安交通大学学报(医学版)

【Objective】 To explore pain and collapse mechanisms in fosteonecrosis of the femoral head (ONFH) with bone marrow edema (BME). 【Methods】 ONFH patients at ARCO Ⅲ stage who underwent total hip arthroplasty in the First Affiliated Hospital of Guangzhou University of Chinese Medicine were enrolled; the femoral head samples, clinical and imaging data were collected. These patients were divided into BME group and non-BME group according to the MR data in one week preoperative. Hematoxylin-eosin and Sirius red staining were performed to observe the morphological changes in bone tissue of femoral head specimens. Western blotting and qPCR were used to semi-quantitatively analyze the expression levels of CTSK, RANKL, and Netrin-1 proteins and mRNA in different regions of the bone tissue. 【Results】 Clinical and imaging data showed that ONFH patients with BME had significantly higher scores of VAS than ONFH patients without BME. Hematoxylin-eosin staining showed that bone structure disorder and a large number of empty bone lacunae were found in the necrotic areas in both groups, but there exited significant granulation tissue in the BME group, and spindle-shaped fibroblastic cells and inflammatory cells aggregated in the repaired region. Sirius red staining revealed the necrotic and sclerotic areas were accumulated with many collagenous fiber in the BME group. The results of Western blotting and qPCR showed that Netrin-1 expressions in the necrotic, sclerotic and health areas in the BME group were higher than those in the non-BME group (P<0.05), while osteoclast related proteins and mRNA expressions of the necrotic and sclerotic areas in the BME group was higher than those in the non-BME group (P<0.05). 【Conclusion】 All these findings indicated that hip pain was positively correlated with femoral head necrosis with BME, hyperactive osteoclasts participated in the femoral head collapse with BME, and the upregulated expression of Netrin-1 mediated the pain mechanism.

Academician TONG Xiaolin's Understanding and Experience in Treating Severe Cases of COVID-19 / 中医杂志

This article highlighted the invaluable expertise of Academician TONG Xiaolin in managing severe cases of COVID-19， thereby providing ideas for the treatment of severe and critically ill patients with SARS-CoV-2 infection by integrating traditional Chinese and western medicine. It is believed that COVID-19 belongs to the “cold dampness epidemic” in traditional Chinese medicine， which is caused by pathogenic qi of cold and dampness. The course of the disease can be divided into four stages： constraint， block， collapse， and deficiency， and the severe cases are mainly in the block and collapse stages. The pathogenesis at the block stage is described as epidemic toxins blocking the lung， which should be treated by diffusing the lung and unblocking the bowels， resolving phlegm and unblocking collaterals. The primary formula used is Zilong Xuanbai Chengqi Decoction （子龙宣白承气汤） with modifications based on individual condition. The pathogenesis at the collapse stage is described as internal block and external collapse， which should be treated by restoring yang to save from collapse， boosting qi to relieve collapse， diffusing the lung and unblocking the bowels， resolving phlegm and unblocking collaterals， usually with the formula Poge Zilong Xuanbai Chengqi Decoction （破格子龙宣白承气汤） with modifications.

Clinical study on core decompression in treating osteonecrosis of the femoral head of the necrotic bone-in different site / 中国骨伤

OBJECTIVE@#To analyze the clinical effect of decompression and bone grafting on osteonecrosis of the femoral head(ONFH) at different sites of necrotic lesions.@*METHODS@#A total of 105 patients with ARCOⅡstage ONFH admitted from January 2017 to December 2018 were retrospectively analyzed. There were 71 males and 34 females, with an average age of (55.20±10.98) years old. The mean course of all patients was(15.91±9.85) months. According to Japanese Inveatigation Committee (JIC) classification, all patients were divided into 4 types:17 cases of type A, 26 cases of type B, 33 cases of type C1 and 29 cases of type C2. All four groups were treated with decompression of the pulp core and bone grafting. Visual analogue scale(VAS) and Harris hip joint score were used before and at 3, 6, 12, and 24 months after the operation, and the collapse of the femoral head was observed by X-ray examination within 2 years.@*RESULTS@#All 105 patients were successful on operation without complications, and the mean follow-up duration was (24.45±2.75) months. Harris score showed that there was no statistical difference among four groups before surgery and 3, 6 months after surgery (P>0.05);at 12 and 24 months after surgery, there were significant differences among all groups (P<0.01). There were significant differences in intragroup Harris scores at preoperative and postoperative time points among four groups (P<0.01). VAS showed that there was no statistical difference among four groups before and 3, 6 months after surgery (P>0.05);at 12 and 24 months after surgery, there were significant differences among all groups (P<0.01). There were significant differences in VAS at preoperative and postoperative time points among four groups (P<0.01). None of the patients in four groups had femoral head collapse before and 3, 6 months after surgery. At 12 months after operation, there were 3 cases of femoral head collapse in group C and 4 cases in group C2(P>0.05);At 24 months after operation, 1 case of femoral head collapse occurred in group B, 6 cases in group C1 and 8 cases in group C2(P<0.05).@*CONCLUSION@#Core decompression and bone grafting can improve the effect of ONFH and hip preservation. The effect of hip preservation for ONFH is closely related to the location of the osteonecrosis lesion, so the influence of the location of lesion on the effect of hip preservation should be considered in clinical treatment, so as to make better preoperative hip preservation plan.

Clinical study on the subchondral screw compression technique assisted reduction of residual or secondary collapse of lateral tibial plateau / 中国修复重建外科杂志

OBJECTIVE@#To explore the reduction and support effect of the subchondral screw compression technique for residual or secondary collapse of the lateral tibial plateau during operation.@*METHODS@#Between January 2020 and June 2021, 11 patients with residual or secondary collapse of the lateral tibial plateau during operation were treated with the subchondral screw compression technique. There were 6 males and 5 females, aged 52.3 years old (range, 27-64 years). The fractures were caused by traffic accident in 10 cases and falling from height in 1 case and located at the left knee in 6 cases and the right knee in 5 cases. According to Schatzker classification, there were 5 cases of type Ⅱ fractures, 4 cases of type Ⅲ fractures, and 2 cases of type Ⅴfractures. According to the three columns classification, there were 5 cases of lateral column, 4 cases of lateral column and posterior column, and 2 cases of three columns. The time from injury to operation was 4.5 days (range, 3-7 days). During the follow-up, X-ray films were obtained and the Rasmussen standard was used to evaluate the quality of fracture reduction, meanwhile fracture healing was observed. The medial proximal tibial angle (mPTA), posterior tibial slope angle (pTSA), and articular surface collapse were measured at immediate and 12 months after operation. The knee joint range of motion was evaluated at last follow-up, and the knee joint function was evaluated using the Hospital for Special Surgery (HSS) score.@*RESULTS@#All operations were successfully completed, with a mean operation time of 71.4 minutes (range, 55-120 minutes), and a mean hospital stay of 8.0 days (range, 5-13 days). The incisions all healed by first intention, without complications such as infection, flap necrosis, or vascular and nerve injury. All patients were followed up 16.5 months on average (range, 12-24 months). X-ray films showed that the fracture reduction score was 14-18 (mean, 16.7) according to Rasmussen score criteria; and 5 cases were rated as excellent and 6 as good. All fractures healed clinically with a mean clinical healing time of 14.9 weeks (range, 12-16 weeks), and there was no complications such as plate or screw loosening. At 12 months after operation, the mPTA and pTSA were (87.5±1.7)° and (6.2±3.1)°, respectively; there was no significant difference when compared to the values at immediate after operation [(87.6±1.8)° and (6.5±3.1)°] ( P>0.05). The articular surface of the tibial plateaus was effectively supported, and it collapsed again by 0-1.0 mm at 12 months, with an average of 0.4 mm. At last follow-up, the knee joint range of motion was 115°-135° (mean, 126.8°) and the HSS score for knee joint function was 87-98 (mean, 93.9). Five patients underwent secondary operation to remove the internal fixator at 12-18 months after operation.@*CONCLUSION@#The subchondral screw compression technique is helpful for the reduction of residual or secondary collapse of the lateral tibial plateau during operation, and can provide good support for osteochondral blocks.

Finite element analysis for predicting osteonecrosis of the femoral head collapse based on the preserved angles / 中国修复重建外科杂志

OBJECTIVE@#To establish finite element models of different preserved angles of osteonecrosis of the femoral head (ONFH) for the biomechanical analysis, and to provide mechanical evidence for predicting the risk of ONFH collapse with anterior preserved angle (APA) and lateral preserved angle (LPA).@*METHODS@#A healthy adult was selected as the study object, and the CT data of the left femoral head was acquired and imported into Mimics 21.0 software to reconstruct a complete proximal femur model and construct 3 models of necrotic area with equal volume and different morphology, all models were imported into Solidworks 2022 software to construct 21 finite element models of ONFH with LPA of 45°, 50°, 55°, 60°, 65°, 70°, and 75° when APA was 45°, respectively, and 21 finite element models of ONFH with APA of 45°, 50°, 55°, 60°, 65°, 70°, 75° when LPA was 45°, respectively. According to the physiological load condition of the femoral head, the distal femur was completely fixed, and a force with an angle of 25°, downward direction, and a magnitude of 3.5 times the subject's body mass was applied to the weight-bearing area of the femoral head surface. The maximum Von Mises stress of the surface of the femoral head and the necrotic area and the maximum displacement of the weight-bearing area of the femoral head were calculated and observed by Abaqus 2021 software.@*RESULTS@#The finite element models of ONFH were basically consistent with biomechanics of ONFH. Under the same loading condition, there was stress concentration around the necrotic area in the 42 ONFH models with different preserved angles composed of 3 necrotic areas with equal volume and different morphology. When APA was 60°, the maximum Von Mises stress of the surface of the femoral head and the necrotic area and the maximum displacement of the weight-bearing area of the femoral head of the ONFH models with LPA<60° were significantly higher than those of the models with LPA≥60° ( P<0.05); there was no significant difference in each index among the ONFH models with LPA≥60° ( P>0.05). When LPA was 60°, each index of the ONFH models with APA<60° were significantly higher than those of the models with APA≥60° ( P<0.05); there was no significant difference in each index among the ONFH models with APA≥60° ( P>0.05).@*CONCLUSION@#From the perspective of biomechanics, when a preserved angle of ONFH is less than its critical value, the stress concentration phenomenon in the femoral head is more pronounced, suggesting that the necrotic femoral head may have a higher risk of collapse in this state.

Pharmacological research progress of five classical prescriptions in treatment of chronic heart failure / 中国中药杂志

Chronic heart failure(CHF) is a comprehensive clinical syndrome caused by multiple factors that result in structural and/or functional abnormalities of the heart, leading to impaired ventricular contraction and/or relaxation functions. This medical condition represents the final stage of various cardiovascular diseases. In the treatment of CHF, multiple clinical studies have demonstrated the benefits of using traditional Chinese medicine(TCM) to control oxidative stress, inflammation, and apoptosis, thereby delaying ventricular remodeling and reducing myocardial fibrosis. In this study, common TCM syndromes in the diagnosis and treatment of CHF in recent years were reviewed and summarized. Five common treatment methods including benefiting Qi and activating blood circulation, enhancing Qi and nourishing Yin, warming Yang for diuresis, eliminating phlegm and dampness, rescuing from collapse by restoring Yang, and corresponding classic prescriptions in prevention and treatment of CHF were concluded under the guidance of TCM syndrome differentiation thinking. Meanwhile, research progress on the modern pharmacological effects of these classic prescriptions was systematically discussed, so as to establish a unique treatment system for CHF by classic prescriptions under the guidance of TCM syndrome differentiation theory and provide innovative diagnosis and treatment strategies for clinical CHF.

Retrospective Study on the Radiographic Wrist Indices in a Nigerian Population.

Background: Evaluation of the degree of carpal collapse using radiographic wrist indices is important in the management of wrist diseases. These indices vary in different population groups, hence, the need for population-specific normal references. This study aimed at assessing the carpal height ratio using wrist radiographs of adult Nigerian patients.Materials and Methods: This retrospective study assessed wrist radiographs stored in the Radiology department of Delta State University Teaching Hospital, Oghara, Nigeria, following institutional approval. Apparently normal unpaired wrist radiographs of 135 adults (54 males and 81 females) were used to assess the 3rd metacarpal length, carpal height and capitate length which were used to calculate the carpal height ratio (CHR) and revised carpal height ratio (CHRr). Statistical Package for Social Sciences (SPSS) version 22 was used to analyze these quantitative variables. Independent t-test and Analysis of Variance (ANOVA) were used to probe for differences in gender groups and 10 years' age-groups respectively. Significance was considered at p<0.05. Results: The mean carpal height, capitate length and length of the 3rd metacarpal was 31.77 mm, 23.34 mm and 67.34 mm respectively. The mean CHR and CHRr was 0.47±0.04 and 1.36±0.07 correspondingly. All variables except CHRr were significantly larger in males than in females (p<0.05). All the parameters had no significant association with the age-groups (p>0.05). Conclusion: The CHR and CHRr in this study were lower than reports from other population groups. This study provides a reference database for our studied population to aid in accurate diagnosis and effective management of carpal collapse.

Prevalence of psychiatric symptoms and associated factors in the adult population from the area affected by the tailings dam rupture - Brumadinho Health Project / Prevalência de sintomas psiquiátricos e seus fatores associados na população adulta da área atingida pelo rompimento da barragem de rejeitos: Projeto Saúde Brumadinho

ABSTRACT: Objective: To examine the prevalence of psychiatric symptoms and associated factors in the adult population of Brumadinho (MG), after the dam collapse. Methods: We included 2,740 participants with information about symptoms of post-traumatic stress disorder (PTSD), depression, anxiety, thoughts of death/self-harm, and poor sleep quality collected in 2021. Prevalence values of all conditions were estimated to compare the prevalence of psychiatric symptoms with the participants' sociodemographic characteristics and place of residence. Pearson's c2 test was used, with Rao Scott's correction. Crude and adjusted logistic regressions estimated odds ratios and 95% confidence intervals to assess the association between psychiatric symptoms and participants' characteristics. Results: The most common condition was depressive symptoms (29.3%), followed by post-traumatic stress symptoms (22.9%) and anxious symptoms (18.9%). Regarding the association between participants' characteristics in the adjusted analysis, being a female and living in a mining area was positively associated with symptoms of PTSD, depression, anxiety, thoughts of death/self-harm, and poor sleep quality. A positive association was also found between high school education and post-traumatic stress symptoms. In contrast a negative association was found between being aged ≥60 years and symptoms of PTSD, depression, and anxiety. Conclusion: High prevalence values were found for all psychiatric symptoms after the dam failure in Brumadinho. Being a female, living in the mining area, being ≥60 years old, and having an educational level were all associated with the psychiatric symptoms investigated.

RESUMO: Objetivo: Examinar a prevalência dos sintomas psiquiátricos e seus fatores associados na população adulta de Brumadinho (MG), após o rompimento da barragem. Métodos: Foram incluídos 2.740 participantes com informações coletadas em 2021 sobre os sintomas de estresse pós-traumático (TEPT), depressão, ansiedade, ideias de morte/automutilação e pior qualidade do sono. Estimaram-se as prevalências de todas as condições. Para a comparação das prevalências dos sintomas psiquiátricos e as características sociodemográficas e local de moradia, empregou-se o teste χ2 de Pearson, com correção de Rao-Scott. Regressões logísticas brutas e ajustadas estimaram os odds ratios e intervalos de confiança de 95%, permitindo a avaliação da associação entre os sintomas psiquiátricos e as características dos participantes. Resultados: Os sintomas depressivos foram a condição mais prevalente (29,3%), seguidos pelos sintomas de TEPT (22,9%) e sintomas ansiosos (18,9%). Com relação à investigação da associação entre as características dos participantes na análise ajustada, observou-se que o sexo feminino e os moradores da área de mineração apresentaram relação positiva com os sintomas de TEPT, depressivos, ansiosos, ideia de morte e pior qualidade de sono. Também se encontraram associação positiva entre a escolaridade de nível médio e os sintomas de TEPT e associação negativa entre aqueles com ≥60 anos e os sintomas de TEPT, depressivos e ansiosos. Conclusão: Altas prevalências foram encontradas para todos os sintomas psiquiátricos após a ruptura da barragem em Brumadinho. Sexo feminino, local de moradia na área de mineração, ≥60 anos e escolaridade foram associados aos sintomas psiquiátricos investigados.

Brumadinho Health Project: food and nutrition insecurity versus socioeconomic statuses and dimensions of the food system after the dam rupture / Projeto Saúde Brumadinho: insegurança alimentar e nutricional versus condições socioeconômicas e dimensões do sistema alimentar após desastre

ABSTRACT Objective: To describe the situation of food insecurity of families according to the socioeconomic characteristics and dimensions of the food system in Brumadinho, state of Minas Gerais, Brazil, after the dam rupture in Córrego do Feijão mine. Methods: This is a descriptive study focused on households carried out from the baseline of the Brumadinho Health Project. Food insecurity, the main outcome, was assessed by the short version of the Brazilian Food Insecurity Scale. Other investigated variables were: socioeconomic data; geographic stratum of the households; family's assets; income; expenses; cultivation of food and animal husbandry for consumption. Descriptive analyses were performed comparing the food insecurity of the household according to the other variables by the χ2 test to compare the proportions. Results: Of the investigated households (n=1,441), 35.1% were facing food insecurity. facing food insecurity had: lower prevalence of masonry households with coating (91.4%; 95%CI 87.7%−94.1% vs. 96.7%; 95%CI 94.9%−97.8%); highest proportion of rudimentary cesspit (16.9%; 95%CI 13.3%−21.2% vs. 9.4%; 95%CI 7.4−11.9); lower prevalence of own and paid-off homes (63.9%; 95%CI 56.8−70.5 vs. 77.3%; 95%CI 72.3−81.7); and income reduction after the dam rupture (33.0%; 95%CI 27.1−39.6 vs. 14.1%; 95%CI 11.2−17.6), when compared with those in a food security situation. Conclusion: The prevalence of food insecurity was high, with report of a reduction in household income after the dam rupture. Moreover, most of the households had worse structural quality and sewage outfall. These results evidence the vulnerability of families and possible violation of the human right to adequate food, denoting the urgency of continuous reparative actions.

RESUMO Objetivo: Descrever a situação de insegurança alimentar das famílias segundo as características socioeconômicas e dimensões do sistema alimentar em Brumadinho, Minas Gerais, Brasil, após desastre. Métodos: Estudo descritivo com foco no domicílio realizado pela linha de base do Projeto Saúde Brumadinho. A insegurança alimentar, desfecho principal, foi avaliada pela Escala Brasileira de Insegurança Alimentar curta. Outras variáveis investigadas foram: socioeconômicas; estrato geográfico do domicílio; ativos (bens); renda; despesas familiares; cultivo de alimentos e criação de animais para consumo. Foram realizadas análises descritivas comparando a insegurança alimentar do domicílio segundo as demais variáveis pelo teste χ2 para comparação das proporções. Resultados: Dos domicílios investigados (n=1.441), 35,1% estavam em situação de insegurança alimentar. As famílias em insegurança alimentar apresentavam: menores prevalências de domicílios de alvenaria com revestimento (91,4%; IC95% 87,7%−94,1% vs. 96,7%; IC95% 94,9%−97,8%); maior proporção de fossa rudimentar (16,9%; IC95% 13,3%−21,2% vs. 9,4%; IC95% 7,4−11,9); menor prevalência de domicílios próprios e quitados (63,9%; IC95% 56,8−70,5 vs. 77,3%; IC95% 72,3−81,7); e redução da renda após o rompimento da barragem (33,0%; IC95% 27,1−39,6 vs. 14,1%; IC95% 11,2−17,6), quando comparadas àquelas em segurança alimentar. Conclusão: A prevalência de insegurança alimentar foi elevada, com relato de redução da renda das famílias após o rompimento da barragem. Ademais, boa parte dos domicílios apresentava pior qualidade estrutural e escoamento de esgoto. Esses resultados evidenciam a vulnerabilidade das famílias e possível violação do direito humano à alimentação adequada, denotando a urgência de ações reparadoras contínuas.

Role of transpalatal advancement pharyngoplasty in management of lateral pharyngeal wall collapse in OSA / Papel da faringoplastia com avanço transpalatino no tratamento do colapso da parede lateral da faringe na AOS

Abstract Introduction Non-response to palatal surgery for OSA is a problem. Residual lateral wall hypopharyngeal collapse is the proposed mechanism of failure. Objective This study aims to evaluate the role of transpalatal advancement pharyngoplasty in non-responders to primary palatal surgery with residual lateral wall hypopharyngeal collapse. Methods This is a retrospective study that was conducted on patients who underwent transpalatal advancement pharyngoplasty for residual lateral wall hypopharyngeal. Inclusion criteria were age greater than 18-years, OSA proved by the polysomnography with apnea hypopnea index >15, lateral wall collapse at the level of hypopharynx as proved by drug-induced sleep endoscopy and had a previous tonsillectomy or previous palatal surgery for OSA. Exclusion criteria were those with no history of tonsillectomy or any other surgery for OSA and those with a missed followup. Data of included patients were collected and included gender, age, polysomnographic data like the apnea hypopnea index, oxygen desaturation and the calculated preoperative Epworth sleepiness scale. The early outcome included symptom improvement as measured by Epworth sleepiness scale score and lateral pharyngeal wall evaluation by nasopharyngoscopic examination in the first postoperative month. Late outcome measurement was performed by the 6-month postoperative polysomnography. Data were analyzed using SPSS program. Results The study included 37 patients with a mean age of (40.43 ± 6.51). The study included 26 men and 11 women. There was a statistically significant improvement of apnea hypopnea index from 37.8 ± 9.93 to 9.9 ± 2.55. In addition, a statistically significant improvement of lowest oxygen saturation from 78.9 ± 3.39 to 83.3 ± 3.31 was encountered. The patients improved clinically, and this improvement was measured by statistically significant improvement of Epworth sleepiness scale score and snoring visual analogue scale. Conclusion Transpalatal advancement pharyngoplasty widens the retropalatal airway and has a great role in the management of the vertical palate phenotype. In addition, it can have a role in the management of lateral walls, especially lateral wall hypopharyngeal collapse.

Resumo Introdução A ausência de resposta à cirurgia palatina para AOS é um problema. O colapso residual da parede lateral da hipofaringe é um mecanismo de falha proposto. Objetivo Avaliar o papel da faringoplastia com avanço transpalatino em pacientes que não responderam à cirurgia palatina primária com colapso residual da parede lateral da hipofaringe. Método Estudo retrospectivo que será feito em casos que receberam faringoplastia com avanço transpalatino para parede lateral da hipofaringe residual. Os critérios de inclusão foram idade maior que 18 anos, AOS comprovada por polissonografia com índice de apneia e hipopneia > 15, colapso da parede lateral ao nível da hipofaringe comprovado por endoscopia do sono induzido por drogas e submetidos a amigdalectomia ou cirurgia palatina anterior para AOS. Os critérios de exclusão foram pacientes sem histórico de amigdalectomia ou qualquer outra cirurgia para AOS e aqueles com perda de seguimento. Os dados dos pacientes incluídos foram coletados e incluíram sexo, idade, dados polissonográficos, como índice de apneia e hipopneia, dessaturação de oxigênio e a escala de sonolência de Epworth calculada no pré‐operatório. O desfecho inicial incluiu melhoria dos sintomas medida pelo escore da escala de sonolência de Epworth e avaliação da parede lateral da faringe por exame nasofaringoscópico no primeiro mês do pós‐operatório. A medida do desfecho tardio foi feita pela polissonografia pós‐operatória de 6 meses. Os dados foram analisados no programa SPSS. Resultados O estudo incluiu 37 pacientes com média de 40,43 ± 6,51 anos. O estudo incluiu 26 homens e 11 mulheres. Houve uma melhoria estatisticamente significante do índice de apneia e hiponeia de 37,8 ± 9,93 para 9,9 ± 2,55. Além disso, foi encontrada uma melhoria estatisticamente significante da menor saturação de oxigênio de 78,9 ± 3,39 para 83,3 ± 3,31. Os pacientes melhoraram clinicamente e essa melhoria foi medida pela melhoria estatisticamente significante no escore da escala de sonolência de Epworth e na escala escala visual analógica do ronco. Conclusão A faringoplastia com avanço transpalatino alarga a via aérea retropalatina e tem um papel importante no manejo do fenótipo do palato vertical. Além disso, ela pode ter um papel no manejo das paredes laterais, especialmente no colapso da parede lateral da hipofaringe.

Revelaciones de la pandemia de COVID-19 / Revelations from the COVID-19 pandemic

Resumen Bajo la premisa de que «las sociedades revelan sus entrañas en momentos críticos y las ocultan o encubren en situaciones de normalidad¼, este ensayo emprende, a partir de caracterizar algunas revelaciones de la pandemia de COVID-19 —que ha puesto en jaque al mundo globalizado—, una crítica propositiva de los basamentos de la civilización. En particular, el mito neoliberal como camino único de progreso humano y el del desarrollo tecnológico como esencia del progreso social y razón principal del quehacer científico. Dentro de las revelaciones significativas destaca el desmantelamiento del Estado de bienestar y de los servicios públicos de salud, que hacen vulnerable a la población ante las pandemias; la devastación planetaria, que favorece su emergencia; y la correlación entre el desplome de las actividades humanas y la mejoría (fugaz) de la vida planetaria, que denota la incompatibilidad radical entre la permanencia del capitalismo neoliberal, que todo lo degrada, y la preservación y el cuidado de la vida en su infinita diversidad ¡la humana incluida! Se propone otra idea de progreso humano: el auge de los valores implicados en la superación espiritual, intelectual, moral y de convivencia en armonía con el ecosistema planetario. Respecto a las razones profundas de la catástrofe, se argumenta que es la propia humanidad por su forma de ser, de pensar, de actuar, de convivir y de relacionarse con el planeta. Por tanto, la conclusión a la que se llega es la urgente necesidad de emprender un camino alternativo en la búsqueda de otro mundo posible, hospitalario y dignificante para todas las formas de vida.

Abstract “Societies unveil their entrails during a crisis and hide or conceal them in normal situations” is the premise of this essay that offers a propositional critique of the foundations of civilization by characterizing some revelations from the COVID-19 pandemic that seriously compromises the globalized world. Especially the neoliberal myth as the only way of human progress, and technological development as the essence of social progress and main reason for scientific research. Among the significant revelations is the dismantling of the Welfare state and public health services, which render the population’s vulnerability in the face of pandemics. Planetary devastation favors its emergence, and the correlation between the despondency of human activities and the (fleeting) improvement of planetary life, which denotes the radical incompatibility between the permanence of neoliberal capitalism that degrades everything and preservation and care of life in its infinite diversity, including human life! Another notion of human progress is proposed: the rise of values involved in the coexistence, and the spiritual, intellectual, and moral growth of the human condition in harmony with the planetary ecosystem. Regarding the deep reasons for the catastrophe, it is argued that it is humanity itself by its way of being, thinking, acting, living together and relating to the planet. Therefore, the conclusion reached is the urgent need to undertake an alternative path in the search for another possible world, hospitable and dignifying for all forms of life.

Analysis on influencing factors of vertebral body height reloss after pedicle screw fixation of thoracolumbar fracture / 中华创伤杂志

Objective:To investigate the related factors of vertebral body height reloss after pedicle screw fixation of thoracolumbar fracture and to determe the optimum prediction point.Methods:A retrospective case control study was made on 215 patients with thoracolumbar fracture admitted to Second Affiliated Hospital of Soochow University from January 2010 to December 2017. There were 155 males and 60 females，aged 21-80 years［（48.6±10.4）years］. According to Denis fracture classification，there were 73 patients with compression fractures（type A in 15 patients，type B in 51，type C in 7），135 burst fractures（type A in 28 patients，type B in 87，type C in 20）and flexion distraction fractures（type A in 4，type B in 2，type C in 1）. All patients were treated by pedicle screw fixation. Follow-up lasted for 12- 48 months［（23.8±8.2）months］. Vertebral body height loss occurred in 86 patients（loss group），but did not in 129 patients（non-loss group）. The two groups were compared concerning sex，age，osteoporosis self-assessment tool for Asians（OSTA），body mass index（BMI），fracture types，number of fractured vertebrae，preoperative sagittal Cobb angle，preoperative degree of vertebral compression，number of screws placed in injured vertebrae，extent of vertebral reset and other related factors. Univariate analysis was used to identify the correlation of those factors with vertebral body height reloss. Multivariate Logistic regression analysis was performed to identify the independent factors for the height reloss with the receiver operating characteristic curve（ROC）and area under the curve（AUC）calculated to evaluate the optimum point in prediction of vertebral height reloss.Results:The two groups showed no significant differences in sex，age，BMI，fracture types，number of injured vertebrae，preoperative sagittal Cobb angle and number of screws placed in injured vertebrae（ P>0.05），but the differences were statistically significant in OSTA，preoperative degree of vertebral compression and extent of vertebral reset（ P<0.05）. According to the univariate analysis，OSTA，preoperative degree of vertebral compression and extent of vertebral reset were significantly correlated with the occurrence of vertebral body height reloss（ P<0.05）. According to the multivariate Logistic regression，OSTA（ OR=1.109，95% CI 0.527-0.685， P<0.05）and preoperative degree of vertebral compression（ OR =0.038，95% CI 0.539-0.689， P<0.05）were significantly related to vertebral body height reloss. The AUC relating OSTA and preoperative degree of vertebral compression to vertebral body height reloss was 0.604 and 0.614，respectively. The optimum prediction point of OSTA and preoperative degree of vertebral compression for vertebral body height reloss was 1.9 and 31.3%，respectively. Conclusions:OSTA and the preoperative degree of vertebral compression are independent risk factors for vertebral body height reloss. OSTA≤1.9 or preoperative degree of vertebral compression ≥31.3% indicates a significantly higher risk of postoperative vertebral body height reloss.

Clinical study on new risk assessment and prediction system for early osteonecrosis of the femoral head / 中国骨伤

OBJECTIVE@#To establish a risk assessment and prediction system for early osteonecrosis of the femoral head (ONFH) in order to predict the collapse risk.@*METHODS@#The risk assessment system for early necrosis and collapse of femoral head was established based on the combination of Steinberg stage, ABC typing and the proportion of the proximal sclerotic rim. Firstly, Steinberg stage system was applied. ABC typing was applied to predict risk in stage I, type C was risk free, type B was low risk, type A and type BC were medium risk, type A-C and type AB were high risk. The classification of proximal sclerotic rim was first applied when the Steinberg stage was Ⅱ-Ⅲ, and type 2 was expected to be low risk. If the classification of proximal sclerotic rimwas type 1, then the ABC typing was applied, type C was risk-free, type B was low risk, type A and type BC were medium risk, type A-C and type AB were high risk. According to this prediction system, the collapse risk of femoral head in 188 cases(301 hips) were predicted by retrospective analysis. All the hips were enrolled at the out-patient department of orthopedic in Guang'anmen Hospital attached to China Academy of Chinese Medical Science. The consistency of the prediction results of three doctors and one doctor at different times were evaluated.@*RESULTS@#Among them, 136 cases were male, 52 were female. 75 cases were single hip, 113 were double hip. The age of the patients wa 19 to 64(42.61±12.07) years. The natural course of disease was 0.33 to 5.00(3.62±1.93) years. 206 hips in 301 hips had collapsed, with a collapse rate of 68.44%. In the risk-free group, none hip had collapsed, with a collapse rate of 0%. In the low-risk group, 9 hip in 91 hips had collapsed, with a collapse rate of 9.89%. In the medium-risk group, 12 hip in 19 hips had collapsed, with a collapse rate of 63.16%. And in the high risk group, 185 hips in 190 hips had collapsed, with a collapse rate of 97.37%. They were significantly differences in their collapse rate (@*CONCLUSION@#The risk assessment and prediction system for early ONFH selects different methods to predict the risk of collapse according to the imaging characteristics of different stages, which is combines with the comprehensive assessment of multiple risk factors. The system is applicable to a wide range, simple operation and convenient for clinical application.

Rompimento das barragens de Fundão e da Mina do Córrego do Feijão em Minas Gerais, Brasil: decisões organizacionais não tomadas e lições não aprendidas / Barragem de Fundão and Mina do Córrego do Feijão dams rupture in Minas Gerais, Brazil: untended organizational decisions and unlearned lessons

Resumo Introdução: rompimentos de barragens de rejeitos de mineração provocaram, em 2015, o maior desastre socioambiental e, em 2019, o maior acidente de trabalho do Brasil, ocasionando, respectivamente, a morte de 19 e 270 trabalhadores e moradores das áreas atingidas. Objetivo: identificar e discutir fatores gerenciais, de operação e de manutenção que podem contribuir para acidentes de rompimento de barragens, assim como sugerir medidas de aprimoramento de sistemas de gestão de empresas mineradoras, de políticas públicas e de normas técnicas que tratem da segurança de barragens. Métodos: ensaio com base em pesquisa documental. Foram utilizados relatórios oficiais sobre os acidentes, publicações técnicas e científicas e legislação pertinente ao tema. Resultados: fatores gerenciais, de operação, de manutenção, de engenharia e do ambiente de trabalho contribuíram para os rompimentos das barragens de Fundão e da mina do Córrego do Feijão. Discutem-se decisões gerenciais que levaram aos dois eventos e são apontadas medidas que poderiam ter evitado os acidentes. Conclusão: evidenciou-se a relevância da autonomia de técnicos e gerências na tomada de decisões, além da necessidade de alterar as normas técnicas utilizadas por empresas e os critérios de licenciamento e controle estatal de atividades que implicam grande risco ambiental e social.

Abstract Introduction: the rupture of mine-tailing dams in Brazil accounted for the largest socio-environmental disaster in 2015, and for the major work-related accident in 2019, causing, respectively, the death of 19 and 270 workers and residents of the affected areas. Objective: this study aimed to identify and discuss management, operational, and maintenance factors that may lead to dam failure, as well as suggest measures to improve management systems of mining companies, public policies, and technical regulations related to dam safety. Methods: essay based on documentary research making use of the accidents official reports, technical and scientific publications, and relevant legislation. Result: factors related to management, operation, maintenance, engineering, and work environment contributed to the dams rupture of Barragem do Fundão and Mina do Córrego do Feijão. We discussed management decisions that led to both events, as well as measures that could have prevented them. Conclusion: the findings highlight the relevance of the technicians' and managers' autonomy in decision-making, besides indicating the need for changing technical standards maintained by companies, and state control, and licensing criteria for activities involving great environmental and social risk.

O colapso do ritmo / The collapse of rhythm / El colapso del ritmo

A autora reflete sobre o tema do ritmo como um elemento fundamental para a continuidade psíquica e estruturante para o registro, na psique, de um relacionamento mãe/bebê harmônico. O acontecimento inusitado e traumático da COVID-19 faz um recorte e vem subjetivar de modo particular a escrita, provocando a criação de novos vértices, entre os quais o tema do colapso. O conceito de Winnicott sobre o medo do colapso é atualizado dentro de tal contexto, em que surgem o vazio, a morte e a não-vida. A filosofia também se faz presente como uma interlocução importante, com passagens de ensaios atuais de filósofos a respeito do impacto da pandemia, refletindo e ilustrando os temas do colapso e do ritmo. Percorre-se o pensamento de René Roussillon e Victor Guerra, através de suas contribuições a respeito do ritmo na vida psíquica e a condição de previsibilidade implícita nessa aquisição. A ressonância desses temas na clínica, a partir do atendimento on-line, é abordada como último aspecto, tendo como referência as contribuições de Alessandra Lemma sobre o setting encarnado (AU)

The author reflects upon the theme of rhythm as a fundamental element for psychic continuity and as a structuring element so that a harmonic mother/baby relationship can be recorded in the psyche. The unexpected and traumatic event of COVID-19 imposes a disruption and subjectivizes writing, in particular, leading to the creation of new vortices, among which the theme of collapse is embedded. Winnicott's concept on the fear of collapse is updated within such context, in which emptiness, death, and non-life emerge. Philosophy is also present as an important form of interlocution, with excerpts from current essays by philosophers regarding the impact of the pandemic, reflecting and illustrating the themes of collapse and rhythm. René Roussillon and Victor Guerra's thoughts are approached, through their contributions on the rhythm of psychic life and the condition of predictability that is implicit in this acquisition. The resonance of these themes in the clinical setting, based on care provided on-line, is addressed as the final aspect, having as reference Alessandra Lemma's contributions about the embodied setting (AU)

La autora reflexiona sobre el tema del ritmo como elemento fundamental para la continuidad psíquica y como factor estructurante para el registro, en la psique, de una relación armoniosa madre/bebé. El evento inusitado y traumático da COVID-19 hace un recorte y viene subjetivar la escritura de una manera particular, ocasionando la creación de nuevos vértices, entre los cuales se inserta el tema del colapso. El concepto de Winnicott del miedo al colapso se actualiza en este contexto, en el que surgen el vacío, la muerte y la no vida. La filosofía también está presente como una interlocución importante, con pasajes de ensayos actuales de filósofos sobre el impacto de la pandemia, reflejando e ilustrando los temas del colapso y el ritmo. Se recorre aún el pensamiento de René Roussillon y Victor Guerra, a través de sus contribuciones con respecto al ritmo en la vida psíquica y la condición de previsibilidad implícita en esta adquisición. La resonancia de estos temas en la clínica, desde el atendimiento en línea, es abordada como último aspecto, teniendo como referencia las contribuciones de Alessandra Lemma sobre el setting encarnado (AU)

Colonialism, science, and health / Colonialismo, ciencia y salud

Abstract In addition to genocide, slavery, and the dispossession of indigenous people, colonialism, as a form of control, meant the suppression of traditional knowledge. The imposition of Christianity, the modern Western paradigm, and modern science that followed perpetrated this suppression. The universal role held by modern science is supported neither by epistemic nor social aspects. It is ineffective and complicit in the collapse of civilization, and it is worsened by comprehensive and unifying ideas to be reduced to an input-process of technological innovation for the benefit of social control industries such as the military, information technology, communication, or health. Furthermore, it suppresses ancestral knowledge related to health and medicine that may be beneficial and must be researched (stimulant medicines). Coupled with the health industry, it promotes the medicalization of life, spreading uncertainty, anxiety, and unease. Therefore, it is an instrument of neocolonialism that imposes its priorities, supplanting problems in subordinated countries, and extracts substantial resources, which is detrimental to social policies and programs. The biggest objection to the universality of modern science is derived from its empiricist and reductionist nature. Through the practically impossible idea of a unifying and explanatory knowledge, it impedes researchers the understanding of the complexity of the world and their historical moment and to act accordingly. It transforms great creative and liberating potential to submissiveness for the interests of capital and its representatives.

Resumen El colonialismo, como forma de dominación, significó, además de genocidio, esclavitud o despojo de pueblos originarios, la supresión de saberes tradicionales perpetrada por la imposición del cristianismo, del paradigma moderno occidental y de la ciencia moderna que le siguió. El carácter universal detentado por la ciencia moderna no se sostiene en lo epistémico ni en lo social; es inoperante con y cómplice del colapso civilizatorio; se empobrece de ideas comprensivas e integradoras para reducirse al insumo-proceso de la innovación tecnológica en provecho de las industrias del control social (militar, informática, de comunicación o de la salud); y suprime saberes ancestrales de la esfera de la salud que encierran beneficios y posibilidades que es preciso investigar (medicina estimulante). Aunada a la industria de la salud, impulsa la medicalización de la vida, preñándola de incertidumbre, angustia y desasosiego. Es instrumento del neocolonialismo al imponer sus prioridades, que suplantan las propias de los países subordinados y sustraen cuantiosos recursos en detrimento de políticas y programas sociales. La mayor objeción a la universalidad de la ciencia moderna deriva de su carácter empirista y reduccionista que, al condicionar la imposibilidad práctica de un conocimiento integrador y explicativo, aleja a los investigadores del entendimiento de la complejidad del mundo, de su momento histórico y de actuar en consecuencia, y transforma la gran potencialidad creativa y liberadora de este enorme contingente en docilidad a los designios de los intereses del capital y sus agentes.