ABSTRACT
Chronic kidney disease (CKD) is becoming a global social problem. It is important to slow down the progression of CKD for economic and social concerns. In recent years, it has been found that colon is one of the vital organs which produce uremic toxins. And enterogenous uremic toxins are closely related to the prognosis of CKD. Theory of gut-kidney axis for the slowdown of CKD progression was raised by foreign scholars and became the research hot spot. Colon therapy with traditional Chinese medicine (TCM) has been widely used in clinical practice and is believed to slow down the progression of CKD by numerous clinical reports. However, low re-search quality and ambiguous results limited its further application. Under the guidance of senior TCM Professor Huang Chunlin, who emphasized the method of draining turbidity through bowels in the management of CKD, from the Nephrology Center, Guangdong Provincial Hospital of Chinese Medicine, as well as the modern theory of gut-kidney axis, we had carried out a series of exploratory researches which will provide data and methodology support for further confirmatory studies and improve its effectiveness.
ABSTRACT
Conventional therapy was given to 260 cases of advanced stage of cancer of colon during the period of 1975 - 1988. Radical operation, palliative resection or changing bowel passage were selected according to the condition of the lesions. Post operative chemo -therapy with integrated Chinese and western medicine were given, or with radiotherapy in some of the cases. Results showed that the 5- year survival rates of II, III, IV stages were 80. 5%, 56. 12%, 21. 73% respectively, the mean 5 -year survival rate being 52. 78%, 45 cases with liver metastasis were also treated with integrated medicine with a 5 - year surivial rate of 22. 2%. The above figures of therapeutic effect and survival rates were all superior to that in cases treated by western medicine alone as reported by domestic exponent units.