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1.
Chinese Journal of Biochemical Pharmaceutics ; (6): 247-248,250, 2017.
Article in Chinese | WPRIM | ID: wpr-620446

ABSTRACT

Objective To investigate the effect of dexmedetomidine on restlessness in recovery stage in patients with limbs fracture undergoing combined intravenous inhalation anesthesia and operation.Methods Eighty patients with limbs fracture undergoing combined intravenous inhalation anesthesia and operation in our hospital were randomly divided into the control group and the dexmedetomidine group,40 cases in each group.Before operation, patients in the dexmedetomidine group were given dexmedetomidine 0.5 μg/kg intravenously in 15 min;patients in the control group were given the same volume of 0.9% saline solution.The recovery time, extubation time, the incidence of restlessness, agitation score and sedation score were compared between the two groups.Results The recovery time and extubation time had no significant difference between the two groups.The incidence of restlessness and agitation score in the dexmedetomidine group were significantly lower than those in the control group(P<0.05),while the sedation score in the dexmedetomidine group was significantly higher than that in the control group(P<0.05).Conclusion Dexmedetomidine can reduce the incidence of restlessness and the degree of restlessness in patients limbs fracture undergoing combined intravenous inhalation anesthesia and operation.

2.
The Journal of Clinical Anesthesiology ; (12): 1049-1050, 2009.
Article in Chinese | WPRIM | ID: wpr-405019

ABSTRACT

Objective To observe the effect of sevoflurane inhalation anesthesia and propofolsevoflurane combined anesthesia on glucose concentrations.Methods Thirty patients undergoinggeneral anesthesia were randomly divided into two groups with 15 cases each.The patients in group Awere anesthetized with sevoflurane inhalation and those in group B with sevoflurane combined withprovofol.Blood concentration of glucose was measured before operation and at 2 h during surgery.Results The blood glucose concentrations in groups of A and B were significantly increased at 2 h during surgery than those before[(6.23±1.45)mmol/L vs.(4.86±0.85)mmol/L and(6.66±blood glucose between the two groups.Conclusion Both sevoflurane inhalation anesthesia and combined propofol and sevoflurane anesthesia can not inhibit the increase of blood glucose duringoperation.

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