Primary Glomerulonephritis with Unique C4d Deposition and Concurrent Non-infectious Intermediate Uveitis: a Case Report and Literature Review

C4 glomerulopathy is a recently introduced entity that presents with bright C4d staining and minimal or absent immunoglobulin and C3 staining. We report a case of a 62-year-old man with C4 glomerulonephritis (GN) and uveitis. He presented to the nephrology department with proteinuria and hematuria. The patient also had intermediate uveitis along with proteinuria and hematuria. A kidney biopsy that was performed in light of continuing proteinuria and hematuria showed a focal proliferative, focal sclerotic glomerulopathy pattern on light microscopy, absent staining for immunoglobulin or C3 by immunofluorescence microscopy, with bright staining for C4d on immunohistochemistry, and electron-dense deposits on electron microscopy. Consequently, C4 GN was suggested as the pathologic diagnosis. Although laser microdissection and mass spectrometry for glomerular deposit and pathologic evaluation of the retinal tissue were not performed, this is the first report of C4 GN in Korea and the first case of coexisting C4 GN and uveitis in the English literature.

Socialización académica de los estudiantes del régimen presencial de la escuela de enfermería de la UCV / Academic socialization of students in the classroom regime of the school of nursing at the UCV

El objetivo general del presente estudio fue describir la socialización académica de los estudiantes del tercer y sexto semestre del régimen presencial de la Escuela de Enfermería de la UCV, en el segundo semestre de 2006. Con tal fin se realizó una investigación descriptiva, transversal y de campo, donde los elementos socializadores evaluados fueron: la identificación, el compromiso, la disposición, la vinculación, el cumplimiento y la satisfacción. La población estuvo constituida por 128 estudiantes en los dos semestres. El muestreo se realizó según la fórmula de poblaciones conocidas, quedando la muestra representada por 33 estudiantes del tercer semestre y 63 del sexto semestre. Se aplicó la encuesta como técnica para la recolección de datos, y como instrumento de medición se realizó escala de Licker con tres alternativas. A través del juicio de expertos se realizó la validez de contenido, de constructo y aparente. El análisis estadístico se realizó de manera global, por dimensiones y por ítemes. En el análisis global y por dimensiones, se aplicó la mediana, y los ítemes se analizaron de manera absoluta y porcentual a través de cuadros y gráficos. Los resultados mostraron una socialización global, con una categoría satisfactoria. Las dimensiones tanto en el tercero como en el sexto semestre se categorizaron como favorables. En el análisis de los ítemes se evidenció que la respuesta a veces fue la que predominó, para el tercer semestre, en las categorías vinculación, cumplimiento e identificación, mientras que en el sexto semestre predominó la categoría a veces en la vinculación, la identificación y la satisfacción. En conclusión: Los elementos socializadores no se encontraron en una proporción que pudieran garantizar una socialización plena

The general mission of the present study was to describe the academic socialization of students on the third and sixth semester of the actual regime of the Nursing School of the UCV, in the second semester of the 2006. With this purpose was made a descriptive, cross-sectional investigation and field work, where the evaluating socializing elements were: identification, compromise, disposition, entail, compliment and satisfaction. The population was constituted by 128 students of both semestral. Sampling was made according to formula of the well known population, and it was represented by 33 students of third semester and 63 of sixth semester. It was applied a survey as a technique for data collection, and as measurement instrument a Scale of Licker was made with three alternatives. Through experts judgment were realized the validity of content, constructo and apparent. Statistical analysis was made in a global manner, by dimensions and items. In the general analysis and for each dimensions was applied the median, and items were analyzing by absolute and percentage statistical way into pictures and graphics. The results reported a global socialization, with a category satisfactory. The dimensions as well on third as sixth semester were categorized as favorable. On the analysis of items was demonstrated that category sometimes was predominant on third semester, on the elements compliment, entailment and identification, whereas on sixth semester the category sometimes predominated on the elements entailment, identification and satisfaction. In conclusion: The socializing elements were not finding on a proportion that could guarantee a full socialization

The immune function injury and its mechanism in drug abuser / 中国组织工程研究

Objective To explore the immune function injury and its mechanism in drug abuser.Methods The immune function changes in 50 drug abusers were compared with normal healthy populations by detection of the indexes of subgroups of Th cells, transformation rate of lymphocytes,IgA,IgM,IgG,IgE,compliment C3,C4,IL 1, IL 2,IL 6 TNF and NO.Result In peripheral blood the percentage of Th1 cell, transformation rate of lymphocyte, IgA, IgM, IgG, IgE content, compliment C4,C4, IL 1, IL 2,IL 6,and TNF levels were significantly lower than normal(P< 0.01).The value of Th1/Th2 was lower than normal as well(P< 0.05).NO content was significantly higher than normal(P< 0.001).Conclusion The mechanism of immune function injury in drug abuser might be correlative to direct injury of drugs and their inhibition effect on the thymus hypothalamus hypophysis adrenal axis.

The New Trend and Counter - plan of the Medical Services Today / 中国医学伦理学

Through analysis on compliment on drawbacks in medical services in a third - grade hospital during the year of 2003 - 2004, the author gives a picture of the stracture of the medical services today and tells a trend of such compliement goes from service itself security and guatity of the services. Facing the now challenge and charges on compliment today, the anthor holds the idea that establishing 3 new principles, 3 nes reformations and 3 new services to make sure the parients are satisfied.