ABSTRACT
【Objective】 To study the characteristics of HIV infection among voluntary blood donors in Shijiazhuang from 2011 to 2021, so as to provide reference for decision making in the control of HIV for blood centers. 【Methods】 The confirmatory results of HIV reactive samples in initial screening among voluntary blood donors from 2011 to 2021 in our center were statistical analyzed. 【Results】 A total of 2 008 299 samples from 1 667 315 blood donors were detected, among which 3 217 samples were HIV reactive and 234 were confirmed positive, with the positive rate at 11.65/100 000 and the prevalence of 14.03/100 000. The prevalence in men was higher than that in women (16.52/100 000 vs 1.39/100 000), in first-time blood donors higher than that in repeated donors (17.27/100 000 vs 8.12/100 000), in whole blood donors higher than that in plateletpheresis donors (12.01/100 000 vs 8.41/100 000), and the differences were statistically significant (P<0.05). The male homosexual transmission was the main routes of transmission, accounting for 62.39% (146/234). And 72% of double-reagent reactive samples were confirmed positive. Four samples were screened in the serological window period and 6 samples were from HIV positive confirmed donors. 【Conclusion】 The HIV prevalence among voluntary blood donors in Shijiazhuang was low. A certain percentage of repeated blood donors got newly infected. NAT could shorten the detection window period of HIV. Since some confirmed positive samples had not been detected out by NAT, publicity and education should be strengthened to reduce the probability of infected or high-risk groups to participate in blood donation.
ABSTRACT
【Objective】 To retrospectively analyze the epidemiological characteristics and regularity of HIV among voluntary blood donors in our hospital, so as to provide help for the formulation of effective coping strategies for voluntary blood donation, reduce the incidence of blood transmitted diseases, and improve blood safety. 【Methods】 HIV infection and population characteristics of voluntary blood donors in our hospital from January 2010 to December 2019 were statistically analyzed. 【Results】 A total of 330 000 blood donations occurred during 2010 to 2019, and 1 024 HIV-infected blood donors were screened out, with a positive rate of 0.31%. The detection rate was the highest in 2016, with 158 cases infected(158/35 889, 0.44%), followed by 151 in 2015(151/37 586, 0.40%), and 42 in 2010(42/20 824, 0.20%). The difference was statistically significant (χ2=88.754, P<0.001). Among the 1 024 HIV-infected patients, 876 were males and 148 females, with a gender ratio close to 6∶1. The majority were aged between 18~35 years old, accounting for 86.13%. 【Conclusion】 The HIV infection rate among voluntary blood donors had been increasing year by year in recent years. Major blood centers should strengthen the health information before blood donation, carry out HIV screening strictly, select blood donors appropriately, establish a stable blood donation team, so as to reduce the discarding rate of blood.
ABSTRACT
Objective In order to understand the characteristics and the distribution of HIV infection among voluntary blood donation population by analyzing the result about anti -HIV confirmed positive blood of the blood donors.Methods In the study,researchers used ELISA three and four generations of reagents to carry out anti -HIV blood test,and used the Western Blot to confirm the result.Results 176 024 cases of blood collected from voluntary blood donors had been made anti -HIV blood test,between June 1999 and June 2014.The result showed that 274 cases were testing positive,accounting for 0.16%,and 27 cases were confirmed positive,accounting for 0.015%. All the confirmed positive bloods were HIV -1 type virus infection.In the confirmed positive,23 male patients accounted for 85.2%,and it was greater than the proportion of women;age ranged from 19 to 30 years (16 cases, accounting for 59.3% of the total number;professional farmers in 13 cases accounted for 48.2% and it was bigger than other occupations;The cultural degree was less than college level;The regional distribution was mainly in Yuci in 9 cases,each of the remaining counties each accounted for 1 ~2 cases,3 cases in the field of mobile staff,students, migrant workers in 1 case.Conclusion The number of confirmed positive is rising up year by year,and the distribution of HIV infection population is widespread and spread from high -risk groups to the general population. According to the recent situation,the author suggests to ensure the blood safety,it is necessary to do that increasing the publicity and recruitment about the voluntary blood donation,and strengthening blood screening efforts.