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AIM:To explore the effect of comprehensive therapy in the treatment of fungal corneal ulcer and clinical outcome. METHODS:A total of 159 cases 159 eyes fungal corneal ulcer patients took comprehensive therapy of 10 measures, followed up more than 3mo to observe the treatment effect and the final visual acuity in our hospital for treatment. RESULTS: The average hospitalization time of fungal corneal ulcer was(12. 11±5. 13) d. A total of 148 cases of 148 eyes were cured, and the cure rate was 93. 1%;improvement in 8 cases, accounted for 5. 0%; 3 cases were ineffective, accounted for 1. 9%. The final visual acuity of 89 eyes ≥0. 3, accounted for 56. 0%(89/159). The final visual acuity of 136 eyes ≥0. 1, accounting for 85. 5%(136/159), and accounting for 91. 9% in 148 cured patients. CONCLUSION: The comprehensive therapy in the treatment of fungal corneal ulcer has higher cure rate and visual acuity.
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Aim: The aim was to study the clinical profile, treatment outcomes, and the magnitude of corneal donor requirement secondary to corneal ulcers in our institute. Materials and Methods: A prospective case series study was carried out on 134 eyes of 134 consecutive patients presenting with corneal ulcers from January 2010 to December 2013 at our tertiary eye care center. Information was recorded about the patient’s age and gender, risk factors, prior therapy, clinical presentation, microbiological work-up, management and its outcome. Results: Majority of the corneal ulcers (46.2%) were seen in patients in the productive age-group (21 and 50 years), with 83% male preponderance. Ocular trauma (47%) with vegetative matter was the main predisposing factor. Of the corneal ulcers, 52.9% were of fungal, followed by viral, bacterial and neurotrophic etiology. At presentation, 11.1% were on topical steroid therapy. Only 41% had microbiological confirmation. About 47.7% healed with significant scarring, 41.7% with minimal scarring and 10.4% progressed to complications. Of the 10% eyes with complications, emergency keratoplasty was done in 4% and evisceration in 2%. 17% of eyes responded to antimicrobial therapy; 60% eyes needed therapeutic keratoplasty. Conclusion: Despite an early and aggressive management, we found that 89% of ulcers healed with corneal scarring and poor visual outcome and 60% eyes needed keratoplasty for visual rehabilitation. Hence, combined public health initiatives, overall improvement in medical care and adopting successful eye bank development models is important to meet the increasing demand for keratoplasty.
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OBJETIVO: describir algunas características clínicas y resultados visuales en pacientes operados de trasplante corneal en el Centro Oftalmológico del Hospital Universitario "Arnaldo Milián Castro". MÉTODOS: se realizó un estudio observacional, descriptivo y transversal, con un universo de 47 pacientes operados de trasplante corneal en el Centro Oftalmológico del Hospital Universitario "Arnaldo Milián Castro", de la provincia de Villa Clara, entre enero de 2010 y diciembre de 2012. Las variables estudiadas fueron: edad, sexo, causa del trasplante corneal, objetivo de la cirugía y agudeza visual mejor corregida antes y después del trasplante. RESULTADOS: los grupos etarios que predominaron fueron los comprendidos entre 60 y 69 años y 70 y 79 años en uno y otro sexos. La causa más frecuente de la queratoplastia fue la queratopatía bullosa pseudofáquica, seguida del leucoma corneal y el rechazo al injerto. CONCLUSIONES: después del trasplante de córnea hay un aumento significativo de la agudeza visual mejor corregida. El trasplante corneal contribuye de manera importante a ofrecer un adecuado nivel de recuperación visual en pacientes con opacidades corneales y prevención de ceguera de origen corneal.
OBJECTIVE: to describe some clinical characteristics and visual outcomes in patients undergoing corneal transplants in the Eye Center "Arnaldo Milian Castro" University Hospital. METHOD: an observational, descriptive, cross-sectional study was carried out in 47 patients undergoing corneal transplants in the Eye Center "Arnaldo Milian Castro" University Hospital in Villa Clara province. The universe consisted of 47 patients. the variables studied were: age, sex, cause of corneal transplant surgery and lens best corrected visual acuity before and after transplantation. RESULTS: the predominant age groups were those between 60 and 69 years and 70 to 79 years in both sexes. The most frequent cause of keratoplasty was pseudophakic bullous keratopathy, followed by corneal scarring and graft rejection, and the goal of surgery that prevailed was the optician. CONCLUSIONS: after the cornea transplant there is a significant increase in best corrected visual acuity. Corneal transplantation contributes significantly to provide an adequate level of visual recovery in patients with corneal opacities and blindness prevention of corneal origin.
Subject(s)
Humans , Male , Female , Middle Aged , Aged , Corneal Transplantation/methods , Corneal Transplantation/rehabilitation , Corneal Opacity/therapy , Epidemiology, Descriptive , Cross-Sectional Studies , Observational StudyABSTRACT
La epidermólisis bullosa es una genodermatosis, que comprende un grupo heterogéneo de enfermedades ampollares de la piel y las mucosas, localizadas en la membrana basal epidérmica y la capa basal del epitelio estratificado queratinizado o mucoso, con la consiguiente fragilidad de la piel y severidad variable en su presentación clínica. Con el objetivo de describir y mostrar los hallazgos oftalmológicos más comunes de esta afección, presentamos un caso cuyos síntomas iniciaron a los dos meses de edad con presencia de vesículas y ampollas localizadas en la región frontal, nasal, mejillas y caras laterales del cuello de la frente y las extremidades superiores e inferiores. Las manifestaciones oftalmológicas comenzaron a los seis meses de edad en ambos ojos con leucoma corneal cicatrizal total, simblefaron en 360º, que alcanzó región perilímbica. Todo lo anterior afectó su desarrollo visual y por consiguiente su desarrollo psicomotor. Esta afección requiere tratamiento multidisciplinario con especial atención a la superficie ocular externa para prevenir alteraciones que afecten la visión.
Epidermolysis bulosa is defined as genodermatosis involving a heterogenous group of blistering diseases in the skin and the mucosas, located in the epidermal basal membrane and the basal layer of the stratified, keratinized or mucosal epithelium, with resulting fragility of the skin and variable severity in its clinical presentation. The most common eye findings of this disease were described and shown. The treatment of epidermolysis bulosa should be multidisciplinary, paying special attention to the outer ocular surface to prevent alterations that may affect the vision.