Staging Sequential Treatment of Ischemic Stroke Based on Syndrome Differentiation of Deficiency and Excess in Eight Principles / 中国实验方剂学杂志

The core of diagnosing and treating diseases in traditional Chinese medicine lies in syndrome differentiation. The eight principles of syndrome differentiation serve as guidance for syndrome differentiation. As one of the eight principles of syndrome differentiation， the differentiation of deficiency and excess is the basic and critical method. Ischemic stroke is currently the leading cause harming the health of Chinese residents. Although the hypotheses about the cause of ischemic stroke have evolved from external wind to the later internal wind and to the modern theory of toxin damaging the brain collaterals， they all believe that this disease is rooted in internal deficiency and external excess. According to available studies， although stroke is characterized by complex pathogenesis and rapid progression of syndromes， the key cause evolution has a regularity， that is， from excess to deficiency. This article analyzes the historical evolution of the etiology， pathogenesis， and syndrome differentiation schemes of stroke. There are diverse schemes for the syndrome differentiation of stroke， which make it difficult to choose in clinical practice. In view of this problem， this paper puts forward a new approach of staging sequential treatment of ischemic stroke based on the differentiation of deficiency and excess according to the evolution law of the key cause of stroke. Furthermore， we conducted a randomized controlled study on 100 patients with ischemic stroke to evaluate this new approach. The results showed that the staging sequential treatment of ischemic stroke based on the differentiation of deficiency and excess demonstrated definite clinical efficacy. In addition， this article reviews the previous research results of our team and the research achievements of other teams to preliminarily explore the relationship between stroke syndromes and biomarkers， aiming to provide an objective basis for unveiling the pathogenesis of stroke. In summary， according to the key cause evolution （from excess to deficiency）， the treatment of ischemic stroke by stages based on differentiation of deficiency and excess can facilitate the rapid intervention and improve the clinical efficacy on ischemic stroke.

Development of the connotation of deficiency and excess and acupuncture reinforcing and reducing theory / 中国针灸

There are connotations on regulating deficiency and excess by acupuncture reinforcing and reducing in (), including regulating and , regulating blood and , regulating weakened body resistance and state of evil domination, regulating the deficiency and excess of syndrome. The deficiency and excess usually mean the objects received reinforcing and reducing, such as tangible blood stasis, pus, water, etc, and invisible . The deficiency and excess had always mean the symptoms of diseases since (), and the reinforcing and reducing of acupuncture was regulating . Therefore the connotations of reinforcing and reducing of acupuncture changed and there were complex acupuncture reinforcing and reducing manipulations. The various deficiency and excess connotations and stressing on acupuncture regulating made important changes for the theories and methods of acupuncture reinforcing and reducing which showed the profound impacts of the philosophical thought of monism in ancient China on acupuncture and moxibustion science.

Statement on the Essence of Identification on the Deficiency and Excess Patterns from Nei Wai Shang Bian Huo Lun and the Relativity be-tween Internal Damage and Exogenous Diseases / 浙江中医药大学学报

Objective]To explore the essence of doubts differentiation from‘Neiwaishangbianhuolun’,the monumental work of the medical practitioner Dongyuan Li in Jin and Yuan Dynasties, and relativity between internal damage and exogenous diseases.[Methods] By means of researching the background of‘Neiwaishangbianhuolun’, analyzing the 13 main differentiations, think about the essence of doubts differentiation; meanwhile, by connecting to the explicate of mechanism of ascending yangqi belonging to exterior-releasing medicine(wind-expel ing drugs) in his representative work‘Piweilun’, discuss the contrary and transforming relationships between exogenous wind-cold and internal damage of the stomach and spleen, comparing to academic thoughts of Zhongjing Zhang’s‘Shanghanlun’. [Results]Realize essence of doubts differentiation from ‘Neiwaishangbianhuolun’ is not exterior or interior of disease location,but deficiency and excess of disease character.By analyzing the functional mechanism of wind-expel ing drugs and relationship among exogenous diseases,wind-expel ing drugs and the stomach and spleen, raise the relativity between internal damage and exogenous diseases. [Conclusions] The revealing of the essence of deficiency and excess differentiations from‘Neiwaishangbianhuolun’, together with knowledge of the functional essence of wind-expel ing drugs and the relevance of internal damage and exogenous diseases, may open the mind partly for syndrome differentiation and medications in the clinic.

Treating chronic obstructive pulmonary disease by treating both deficiency and excess / 中华中医药杂志

Professor HONG Guang-xiang is one of the first group of prestigious TCM experts in china.He is a famous expert in internal medicine of TCM and skilfuls at treating pulmonary disease.Reinforcing deficiency and purging excess is the principle of treating chronic obstructive pulmonary disease(COPD).There are different symptom of xu-shi in different period of COPD,the article introduces the thinking and unique experience prescription of HONG Guang-xiang about treating both deficiency and excess basis on the stage of COPD.

A New Model of the Relations among the Five Basic Elements (The Second Report)-The Construction of a Disease Model related to Changes in Deficiency and Excess- / 全日本鍼灸学会雑誌

It is generally known that oriental medicine is based on the concept of deficiency and excess to explain disease in a complex living system. However, a disease model based upon the expression of the relationship between the rhythm of the five basic elements and the living body's control system has not been proposed. Therefore, we investigated this relationship by modeling “Kyo-Ja” and “Jitsu-Ja” on abnormal rhythms of the five basic elements.<BR>We constructed models that always reflect changes in the rhythm of the five basic elements to show that disease occurs by breaking these control systems. The present model suggests that treatments of disease should not only incorporate the characteristics of the five basic elements but should also consider the course of a disease and the patient's overall condition.