ABSTRACT
Objective To promote the rational antibacterial drug use for common digestive system (DS) diseases by reviewing the clinical application of antibacterial drugs for hospitalized patients, formulating the hospital clinical specification of antibacterial drugs for common DS diseases and establishing the clinical application of antibacterial drug differentiation index for DS department.Methods 300 cases were selected from 2 060 hospitalized DS patients in the year 2014 based on the given disease ratio.The usage rate and intensity of antibiotics were calculated with survey and medical statistical analysis.The differentiation index for the clinical application of antibacterial drugs were established.Results Theoretical values of usage rate and use intensity of antibiotics in DS department were 29.0%, 41.5 DDDs according to analysis.However, the practical values were 40.3%, 50.3 DDDs.Conclusion It is necessary to improve the level of clinical antibacterial drug use.One effective way to achieve such goal is to establish the differentiation index of antibacterial drug clinical application for the department.
ABSTRACT
Objective To formulate the clinical application specification of antibiotics ,make a deference index of antibac-terial drugs in chest department according to the investigation about the antibiotics′utility situation in chest department in 2014 and provide a theoretic foundation for the clinical doctor to promote the clinical rational drug use .Methods The antibiotics′ap-plication information of 300 cases inpatients in the chest department of a hospital in 2014 were researched and analyzed through retrospection ,regarding with the relevant regulations and related clinical practice guidelines ,the clinical application specifica-tion of antibiotics was formulated and the analysis ,calculation ,statistics to the actual and theoretical value of the rate and inten-sity of antibiotics′application ,the application rate of the prophylactic antibiotics of type I incision on the inpatients in the chest department had been done .The differentiation index of them were establish .Results The rates of the actual antibiotics′appli-cation and the prophylactic antibiotics of type I incision respectively were 72 .7% and 92 .6% ,while the intensity of antibiotics′application was 61.2 DDDs/(100 persons · d ) . The deference indexes of them were developed 69 .3% , 63 .0% and 49.3 DDDs/(100 persons · d) .Conclusions There′re still much irrational places in the use of antibiotics in chest department of the hospital .It′s essential to strengthen supervision in order to promote the rational use of antibiotics in clinical practice .
ABSTRACT
Objective: To study the genetic diversity of Liriope muscari. Methods: The genetic diversity of 47 populations was analyzed by SRAP marker technique. Results: Fifteen primers amplified 323 polymorphic bands, and the average percentage of polymorphic bands reached to 88.47%. The average of polymorphism information content (PIC) was 0.90. Nei's gene diversity index (H) was 0.197 7 and Shannon's information index (I) was 0.319 0. Gene differentiation index (Gst) was 0.252 8. Cluster analysis using UPGMA method showed that genetic similarity coefficient ranged in 0.59-0.99. Conclusion: L. muscari shows higher genetic diversity and the majority of genetic variation occurs in populations.