ABSTRACT
[Objective] To discuss treatment according to syndrome differention of TCM (traditional Chinese medicine) on double heart disease from the view of Wu Zang Yi Ti.[Method] Based on the theory of Wu Zang Yi Ti from Huangdi Nei Jing and many ancient doctors,discuss the relation between heart and sense,heart and the other four viscera,and treat double heart disease from the etiology and pathogenesis of liver,spleen,kidney,lung and the contact of emotion and five viscera.[Result] The heart is closely related with emotional changes and plays a key role in emotion and viscer.Emotional disorders can promote the progress of double heart disease.So we must base on the characteristics of clinical syndromes when we treat the double heart disease and determine treatment from liver,spleen,kidney and lung.[Conclusion] Discriminating and treating double heart disease from the view of Wu Zang Yi Ti can help us grasp the etiology and pathogenesis of double heart disease better and hold the essence of the disease,so we can achieve the goal of curing for disease roots,and treating both root causes and symptoms.It is helpful to improve the clinical curative effect and improve the quality of life of patients with double heart disease.
ABSTRACT
To evaluate the clinical effect and safety of Xinkeshu Tablets on the double heart disease in coronary heart disease with depression systematically. The relative randomized controlled trials about Xinkeshu Tablets in the treatment of double heart disease in coronary heart disease with depression from 1979 to 2015 were searched in database like CNKI, WanFang data, CBM, Embase, Pubmed, and Cochrane Library. Studies were screened, data were extracted, and methodological quality was evaluated. Meta-analysis was then performed using Review Manager 5.1 software. Totally 11 kinds of studies and 961 patients were involved in this study. Xinkeshu Tablets combined with conventional Western medicine therapy was superior to pure conventional Western medicine therapy in clinical effect of coronary heart disease and improve of HAMD scores with the RR of 1.15 (1.07, 1.23) and 1.39 (1.07, 1.79) respectively. On the basis of available evidence, Xinkeshu Tablets combined with conventional Western medicine therapy has a certain effect on the double heart disease in coronary heart disease with depression, but more clinical study with big samples and high quality should be done to confirm the efficacy and safety.