ABSTRACT
Objective To explore the application value of Supportan in elderly bedridden patients with enteral nutrition (EN) support. Methods Forty cases of elderly bedridden patients admitted to the Department of Intensive Care Unit (ICU) of Hangzhou First People's Hospital from January 2015 to January 2016 were enrolled, Supportan was injected through an indwelling naso-intestinal tube on the basis of routine treatment, and the changes of blood biochemical parameters of EN [serum albumin (Alb), pre-albumin (PA), total lymphocyte count (LYM)] and immune indexes (IgG, IgM, IgA) were monitored before and after EN treatment. Results Ten days after EN treatment, the serum Alb, PA, LYM, IgG, IgM were significantly higher than those before treatment, the differences being statistically significant [Alb (g/L): 30.29±1.65 vs. 28.31±1.72, PA (g/L): 0.25±0.05 vs. 0.23±0.02, LYM (×109): 1.69±0.28 vs. 1.47±0.32, IgG (g/L): 11.54±0.96 vs. 10.69±0.70, IgM (g/L): 1.21±0.19 vs. 0.95±0.13, all P < 0.05]; 20 days after EN treatment, above indexes were increased more significantly compared with those 10 days after EN treatment [Alb (g/L): 34.16±2.41 vs. 30.29±1.65, PA (g/L): 0.28±0.03 vs. 0.25±0.05, LYM (×109/L): 1.96±0.31 vs. 1.69±0.28, IgG (g/L): 14.56±0.77 vs. 11.54±0.96, IgM (g/L): 1.56±0.18 vs. 1.21±0.19, all P < 0.05], 10 days, 20 days after EN treatment, IgA shown a tendency increased, there was no statistical significant difference compared with that before treatment (g/L: 2.63±0.33, 2.67±0.11 vs. 2.61±0.27, both P > 0.05). Conclusion Supportan has important clinical significance in improving the nutritional status and immune function of elderly bedridden patients.
ABSTRACT
Two cases of bedridden patients effectively treated with the Kampo formula Ogikenchu-to are reported. The first case was a 76-year-old female. She had been admitted to a hospital for about five months due to subarachnoid hemorrhage and had been bedridden because of a lack of volition. She was transferred to Riverside Hospital for rehabilitation. At the time of her admittance, her legs were paralyzed with disuse atrophy and her activity of daily living was very restricted. The authors prescribed Ogikenchu-to for her. Her activity of daily living (ADL) showed improvement day by day, and she was finally able to walk with the help of a walking supporter.<br>The second case involved an 86-year-old female who was hospitalized in a clinic with a compression fracture of the lumbar spine. She had been bedridden for about two years. After being transferred to Riverside Hospital for rehabilitation. Ogikenchu-to was administered. Her willingness to participate in rehabilitation gradually improved. She regained the ability to sit up straight, and could walk with a cane. She now enjoys her life with her family.<br>These clinical case studies suggest that Ogikenchu-to may be useful in the treatment of aged bedridden patients.